Results 261 to 270 of about 949,782 (341)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Transient cyanobacteria drive hydrostatic photogranulation but disappear during microbial succession. [PDF]

Biofilm
Galea-Outón S, Hamelin J, Milferstedt K.   +2 more
europepmc   +1 more source

Guerres de succession

, 2001
Patrick Sultan
openalex   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Correction: Effects of experimental canopy openness on wood-inhabiting fungal fruiting diversity across succession. [PDF]

Sci Rep
Schreiber J, Baldrian P, Brabcová V, Brandl R, Kellner H, Müller J, Roy F, Bässler C, Krah FS.   +8 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Integrated metagenomic and 16S rRNA analysis reveals temporal associations between resistance genes and microbial communities during dairy manure composting. [PDF]

Sci Rep
Zhou Y, Liu K, Gong P, Wu J, Ren Z, Jin E.   +5 more
europepmc   +1 more source

The European Regulation on Successions and Wills and new perspectives for national legal systems

, 2017
Giovanna Debernardi
openalex   +1 more source

Rapid Succession within the Veillonella Population of a Developing Human Oral Biofilm In Situ

, 2006
Robert Palmer, Patricia I. Diaz, Paul E. Kolenbrander   +2 more
openalex   +1 more source