Results 31 to 40 of about 667 (143)

Long-term follow-up of elemental mercury injection: a case report

Toxicology Communications
Introduction Chronic elemental mercury (Hg0) toxicity from subcutaneous or intravenous deposits is a rare phenomenon. We report a case of mercury toxicity following injection in the leg, resulting in elevated mercury concentrations that we monitored over
Travis Mok, Joseph Ebersole, Kyle Suen, Nicholas Titelbaum, Emily Kiernan, Ziad Kazzi, Joseph Carpenter   +6 more
doaj   +1 more source

A Challenging Case of Acute Mercury Toxicity

Case Reports in Medicine, 2018
Background. Mercury exists in multiple forms: elemental, organic, and inorganic. Its toxic manifestations depend on the type and magnitude of exposure. The role of colonoscopic decompression in acute mercury toxicity is still unclear.
Ali Nayfeh, Thamer Kassim, Noor Addasi, Faysal Alghoula, Christopher Holewinski, Zachary Depew   +5 more
doaj   +1 more source

Uso de succimer como quelante en intoxicación crónica por mercurio: un reporte de caso

Revista de la Facultad de Ciencias de la Salud, 2020
Introducción: La intoxicación crónica por mercurio inorgánico en la industria se presenta con un amplio espectro de manifestaciones clínicas, destacándose las del sistema nervioso central.
Juan Pablo Zapata Díaz, Juliana Mesa Arango, Marie Claire Berrouet Mejía   +2 more
doaj  

A Comparison of Monte Carlo Based Marginal Likelihood Estimators

WIREs Computational Statistics, Volume 18, Issue 1, March 2026.
Comparison of marginal likelihood estimation methods. ABSTRACT Marginal likelihood plays a central role in Bayesian model comparison and hypothesis testing, but its computation is often challenging in practice. This article reviews recent Monte Carlo methods that rely on the availability of Markov chain Monte Carlo (MCMC) samples from the posterior and
Aolan Li, Pang‐Yu Liu, Yu‐Bo Wang, Analisa Milkey, Paul O. Lewis, Ming‐Hui Chen   +5 more
wiley   +1 more source

THERAPEUTIC EFFICACY OF ALPHA LIPOIC ACID IN COMBINATION WITH SUCCIMER AGAINST LEAD-INDUCED OXIDATIVE STRESS, HEPATOTOXICITY AND NEPHROTOXICITY IN RATS التأثير العلاجي لحامض الألفاليبوک عند إضافته للسکسمر المضاد للجهد المؤکسد والتسمم الکبدي والکلوي للرصاص في الجرذان [PDF]

Assiut University Bulletin for Environmental Researches, 2008
: Lead toxicity is a worldwide health problem due to continuous exposure of the population to lead in the environment especially workers in industries. It affects many body organs especially the liver and kidneys.
doaj   +1 more source

Exposure the Hazardous Potential of Quinalphos: An In‐Depth Analysis for Environmental and Biological Effects on Human Health

IET Systems Biology, Volume 20, Issue 1, January/December 2026.
This study elucidates pesticide docking onto proteins encoded by differentially expressed genes, revealing interaction networks involving chemicals, genes, proteins, drugs and diseases. It highlights structural insights, regulatory pathways and potential therapeutic or environmental implications, providing a comprehensive understanding of the ...
Jyoti Kant Choudhari, Biju Prava Sahariah, Anand Kumar Jayapal, Jyotsna Choubey, Abhishek Tripathi   +4 more
wiley   +1 more source

New cases of δ‐aminolevulinic acid dehydratase deficiency: Functional insights into gene variants using an innovative mouse liver model

Journal of Internal Medicine, Volume 299, Issue 1, Page 126-142, January 2026.
Abstract Background Dysfunction of δ‐aminolevulinic acid dehydratase (ALAD), the second enzyme involved in heme biosynthesis, leads to two pathologies: genetic and acquired. The genetic form is an ultrarare, severe childhood‐onset disease inherited in an autosomal recessive manner, whereas the acquired form usually affects adults due to enzyme ...
Elena Di Pierro, Isabel Solares, Daniel Jericó, Francisco J. Castelbón, Javier Tomás Solera, Antoni Riera‐Mestre, María Barreda‐Sánchez, Carlo Poci, Annamaria Nicolli, Francesco Urigo, Ana Sampedro, Rafael Enríquez de Salamanca, Matteo Marcacci, Matías A. Ávila, Pauline Harper, Marta G. Fanlo‐Maresma, Encarna Guillén‐Navarro, Giovanna Graziadei, Andrea Wenzel, Bodo B. Beck, Paolo Ventura, Montserrat Morales‐Conejo, Antonio Fontanellas   +22 more
wiley   +1 more source

Efficacy of Succimer Chelation of Mercury at Background Exposures in Toddlers: A Randomized Trial [PDF]

The Journal of Pediatrics, 2009
To examine whether succimer, a mercaptan compound known to reduce blood lead concentration in children, reduces blood mercury concentration.We used samples from a randomized clinical trial of succimer chelation for lead-exposed children. We measured mercury levels in pre-treatment samples from 767 children.
Yang, Cao, Aimin, Chen, Robert L, Jones, Jerilynn, Radcliffe, Kim N, Dietrich, Kathleen L, Caldwell, Shyamal, Peddada, Walter J, Rogan   +7 more
openaire   +2 more sources

Chronic Lead Exposure and Tauopathies: Molecular Mechanisms of Neurotoxicity and Emerging Nanotherapeutic Strategies

Journal of Toxicology, Volume 2026, Issue 1, 2026.
Chronic exposure to lead (Pb) remains a critical global public health challenge, extending beyond its established neurotoxic effects to its emerging role in the pathogenesis of neurodegenerative disorders, particularly tauopathies. Accumulating evidence indicates that prolonged Pb exposure disrupts neuronal homeostasis through multiple interconnected ...
Maryam Ebrahimi, Mahsa Javan, Mahdi Alijanianzadeh, Lissinda H. Du Plessis   +3 more
wiley   +1 more source

Oral Succimer Decreases the Gastrointestinal Absorption of Lead in Juvenile Monkeys [PDF]

Environmental Health Perspectives, 2001
Although succimer (Chemet, meso-2,3-dimercaptosuccinic acid, DMSA) is considered to be a safe and effective chelating agent for the treatment of lead poisoning in humans, there is concern that it may increase the gastrointestinal (GI) absorption and retention of Pb from exposures suffered concurrent with treatment. This concern is justified because the
J D, Cremin, M L, Luck, N K, Laughlin, D R, Smith   +3 more
openaire   +2 more sources