Results 1 to 10 of about 2,402,251 (269)

The Role of Iron Chelation Therapy in Colorectal Cancer: A Systematic Review on Its Mechanisms and Therapeutic Potential [PDF]

Cancer Medicine
Background Despite significant therapeutic advancements in recent decades, colorectal cancer (CRC) continues to exhibit high rates of mortality and morbidity.
Gihani Vidanapathirana, Md Sajedul Islam, Sujani Gamage, Alfred K. Lam, Vinod Gopalan   +4 more
doaj   +3 more sources

Endocrine Complications and the Effect of Compliance with Chelation Therapy in Patients with Beta Thalassemia Major in Eastern Province of Saudi Arabia [PDF]

Journal of Blood Medicine, 2022
Fatema Habbash,* Wegdan Al-Bati,* Howra Al-Hashim,* Maryam Aldossari,* Ahmed Alali, Khalid Alalyani, Zainab Al-Ebrahim, Nouf Hamed, Samma Eraqe, Ziyad Binayfan, Azzam Al Marri, Thamer Aljaber Department of Family and Community Medicine ...
Habbash F, Al-Bati W, Al-Hashim H, Aldossari M, Alali A, Alalyani K, Al-Ebrahim Z, Hamed N, Eraqe S, Binayfan Z, Al Marri A, Aljaber T   +11 more
doaj   +3 more sources

Barriers to adherence to iron chelation therapy among adolescent with transfusion dependent thalassemia [PDF]

Frontiers in Pediatrics, 2022
Study backgroundThalassemia is the commonest genetic blood disorder in Malaysia which requires life-long blood transfusions. From a total of 7,984 thalassemia patients in Malaysia, adolescent age group account for the highest number of patients (2,680 ...
Rafaa Mohamed, Amir Hamzah Abdul Rahman, Farin Masra, Zarina Abdul Latiff   +3 more
doaj   +2 more sources

A MULTICENTER ICET-A STUDY ON AGE AT MENARCHE AND MENSTRUAL CYCLES IN PATIENTS WITH TRANSFUSION-DEPENDENT THALASSEMIA (TDT) WHO STARTED EARLY CHELATION THERAPY WITH DIFFERENT CHELATING AGENTS. [PDF]

Mediterranean Journal of Hematology and Infectious Diseases, 2023
. Objective: To evaluate the age at menarche and menstrual characteristics in patients with transfusion-dependent thalassemia (TDT) who started early chelation therapy (≤ 3 years) with a variety of chelating agents.
SALVATORE DI MAIO, VINCENZO DE SANCTIS, PIERLUIGI MARZUILLO, CHRISTOS KATTAMIS, SHAHINA DAAR, MEHERAN KARIMI, SAKI FOROUGH, ATANAS BANKEV, VALERIA KALEVA, SOTEROULA CHRISTOU, CARMELO FORTUGNO, POLYXENI DELAPORTA, ASHRAF T SOLIMAN , PLOUTARCHOS TZOULIS   +13 more
doaj   +2 more sources

Case Report: Mercury exposure and anti-LGI1/Caspr2 autoimmune encephalitis: a case series and literature review on the paradoxical worsening after chelation therapy [PDF]

Frontiers in Immunology
BackgroundChronic mercury exposure may be a potential risk factor for anti-LGI1/Caspr2 autoimmune encephalitis (AE). The effect of chelation therapy on coexisting AE is unknown.MethodsWe report three patients from West China Fourth Hospital, Sichuan ...
Chao Huang, Chao Huang, Tao Chen, Tao Chen, Ge Tan, Ge Tan, Junming Li, Ling Liu   +7 more
doaj   +2 more sources

A systematic review of adherence to iron chelation therapy among children and adolescents with thalassemia [PDF]

Annals of Medicine, 2022
Sherif M Badawy, Margaret Locke
exaly   +2 more sources

Predictors of Non-adherence to iron chelation therapy in pediatric thalassemia patients

Journal of Rawalpindi Medical College, 2022
Objective: This study was conducted to identify predictors of non-adherence to iron chelation therapy among children suffering from β-thalassemia major across different treatment regimens.
Muniba Kanwal, Rizwan Shafeeq Ahmad, Naima Tariq, Gul -e- Rehan   +3 more
doaj   +1 more source

Use of deferoxamine (DFO) in transfusion-dependent β-thalassemia during pregnancy: A retrospective study

Taiwanese Journal of Obstetrics & Gynecology, 2020
Objective: To report cases of use of chelation therapy during pregnancy which resulted in favorable outcomes for the babies. Materials and methods: In this retrospective cohort study, we described the evolution and outcome of 9 pregnancies in Italian ...
Maria Grazia Piccioni, Carmela Capone, Flaminia Vena, Valentina Del Negro, Michele Carlo Schiavi, Valentina D'Ambrosio, Antonella Giancotti, Maria Paola Smacchia, Roberto Brunelli   +8 more
doaj   +1 more source

Compliance and clinical benefit of deferasirox granule and dispersible tablet formulation in pediatric patients with transfusional iron overload: in a randomized, open-label, multicenter, phase II study

Haematologica, 2023
CALYPSO (clinicaltrials gov. Identifier: NCT02435212), a randomized, open-label, multicenter, phase II study evaluated the compliance, clinical benefits, and safety of deferasirox granules and dispersible tablets (DT) in pediatric patients with iron ...
Ali T. Taher, Yasser Wali, Maria Cecilia Cruz, Pimlak Charoenkwan, Yesim Aydinok, Olena Werner, Sameera Govindaraju, Fabian Romen, Vip Viprakasit   +8 more
doaj   +1 more source

Cardiac iron overload evaluation in thalassaemic patients using T2* magnetic resonance imaging following chelation therapy: a multicentre cross-sectional study

Hematology, Transfusion and Cell Therapy, 2023
Introduction: Magnetic resonance imaging (MRI) T2* technique is used to assess iron overload in the heart, liver and pancreas of thalassaemic patients. Optimal iron chelation and expected tissue iron response rates remain under investigation.
Eduardo Cerello Chapchap, Murilo Marques Almeida Silva, Reijane Alves de Assis, Lucila Nassif Kerbauy, Michelli da Silva Diniz, Laércio Alberto Rosemberg, Sandra Regina Loggetto, Aderson da Silva Araujo, Antonio Fabron Junior, Monica Pinheiro de Almeida Verissimo, Giorgio Roberto Baldanzi, Breno Pannia Esposito, Fernando Tricta, Merula Emmanoel Anargyrou Steagall, Claudia Ângela Galleni Di Sessa Vellozo, Kleber Yotsumoto Fertrin, Ronaldo Hueb Baroni, Nelson Hamerschlak   +17 more
doaj   +1 more source