Results 1 to 10 of about 70,599 (218)

Cognitive Impairment in Children with Beta-Thalassaemia Major at a Tertiary Care Centre, Rajasthan, India: A Cross-sectional Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2023
Introduction: Thalassaemia is one of the most common genetic disorders. Iron overload due to repeated blood transfusions and chelating therapy leads to oxidative stress and possible irreversible brain tissue damage, causing cognitive impairment in these ...
Sandeep Avasarala   +4 more
doaj   +1 more source

Preparation and Characterization of an Oyster Peptide–Zinc Complex and Its Antiproliferative Activity on HepG2 Cells

open access: yesMarine Drugs, 2023
It is evident that zinc supplementation is essential for maintaining good health and preventing disease. In this study, a novel oyster peptide–zinc complex with an average molecular weight of 500 Da was prepared from oyster meat and purified using ...
Bo Peng, Zhu Chen, Yejia Wang
doaj   +1 more source

Cooking Alters the Metabolites of Onions and Their Ability to Protect Nerve Cells from Lead Damage

open access: yesFoods
Onions (Allium cepa L.) are nutritious vegetables; however, variations in processing methods can influence their chemical composition and functional properties. Raw processing and cooking are the two main food-processing methods for onions, but it is not
Li Zhao   +6 more
doaj   +1 more source

Exploring the Use of Intracellular Chelation and Non-Iron Metals to Program Ferroptosis for Anticancer Application

open access: yesInorganics
The discovery of regulated cell death (RCD) revolutionized chemotherapy. With caspase-dependent apoptosis initially being thought to be the only form of RCD, many drug development strategies aimed to synthesize compounds that turn on this kind of cell ...
Oscar Claudio-Ares   +10 more
doaj   +1 more source

Enhanced Water Absorbency and Water Retention Rate for Superabsorbent Polymer via Porous Calcium Carbonate Crosslinking

open access: yesNanomaterials, 2023
To improve the water absorbency and water-retention rate of superabsorbent materials, a porous calcium carbonate composite superabsorbent polymer (PCC/PAA) was prepared by copolymerization of acrylic acid and porous calcium carbonate prepared from ground
Yixin Jiao   +6 more
doaj   +1 more source

Amending Potassic Fertilizer with Charcoal and Sago (Metroxylon sagu) Bark Ash to Improve Potassium Availability in a Tropical Acid Soil

open access: yesAgronomy, 2021
In Ultisols and Oxisols, potassium (K) in the soil solution is leached from the rhizosphere before it interacts with soil colloids, or exchanged with other cations at the exchange sites of the soils because of the abundance of kaolinite clay minerals ...
Puvan Paramisparam   +5 more
doaj   +1 more source

Validation of R2* magnetic resonance imaging for quantifying secondary iron overload in pediatric patients

open access: yesDiagnostic and Interventional Radiology
PURPOSE: Non-invasive assessment of iron deposition is the standard of care for guiding chelation therapy in patients with iron overload. Several magnetic resonance imaging (MRI)-based techniques have been developed. This study compares the MRI-based R2*
Tahani M. Ahmad   +4 more
doaj   +1 more source

Cleavage of the Pt-I bond in a Primary Cycloplatinated Amine by Chelation

open access: yesCrystals, 2015
In the square-planar cycloplatinated complex of R–phenylethylamine, both additional substituents, an anionic iodo and a neutral donor ligand, have been replaced by chelating ethylenediamine.
William Raven   +2 more
doaj   +1 more source

Harzianic Acid Activity against Staphylococcus aureus and Its Role in Calcium Regulation

open access: yesToxins, 2023
Staphylococcus aureus is a Gram-positive bacterium, which can be found, as a commensal microorganism, on the skin surface or in the nasal mucosa of the human population. However, S.
Alessia Staropoli   +8 more
doaj   +1 more source

Cerebral Iron Deposition in Neurodegeneration

open access: yesBiomolecules, 2022
Disruption of cerebral iron regulation appears to have a role in aging and in the pathogenesis of various neurodegenerative disorders. Possible unfavorable impacts of iron accumulation include reactive oxygen species generation, induction of ferroptosis,
Petr Dusek   +4 more
doaj   +1 more source

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