Results 11 to 20 of about 136,503 (303)

Chelation in Antibacterial Drugs: From Nitroxoline to Cefiderocol and Beyond

Antibiotics, 2022
In the era of escalating antimicrobial resistance, the need for antibacterial drugs with novel or improved modes of action (MOAs) is a health concern of utmost importance.
Davorka Repac Antić, Marijo Parčina, Ivana Gobin, Mirna Petković Didović   +3 more
doaj   +1 more source

Phosphorus Transformation in Soils Following Co-Application of Charcoal and Wood Ash

Agronomy, 2021
Phosphorus (P) is a vital soil macronutrient required by plants for optimum growth and development. However, its availability is limited because of fixation. The phosphorus fixation reaction is pH dependent.
Prisca Divra Johan, Osumanu Haruna Ahmed, Latifah Omar, Nur Aainaa Hasbullah   +3 more
doaj   +1 more source

Co-Application of Charcoal and Wood Ash to Improve Potassium Availability in Tropical Mineral Acid Soils

Agronomy, 2021
Potassium (K) is a macronutrient required by plants for energy production, enzyme activation, formation of cell wall, production of protein, and photosynthesis. However, K in the soil solution is leached from the rhizosphere before it interacts with soil
Puvan Paramisparam, Osumanu Haruna Ahmed, Latifah Omar, Huck Ywih Ch’ng, Prisca Divra Johan, Nur Hidayah Hamidi   +5 more
doaj   +1 more source

Interaction of 2,6,7-Trihydroxy-Xanthene-3-Ones with Iron and Copper, and Biological Effect of the Most Active Derivative on Breast Cancer Cells and Erythrocytes

Applied Sciences, 2020
Metal chelators can be potentially employed in the treatment of various diseases, ranging from metal overload to neoplastic conditions. Some xanthene derivatives were previously reported to complex metals.
Přemysl Mladěnka, Jana Karlíčková, Marcel Hrubša, Elma Veljović, Samija Muratović, Alejandro Carazo, Akash Shivling Mali, Selma Špirtović-Halilović, Luciano Saso, Milan Pour, Kemal Durić   +10 more
doaj   +1 more source

Cu²⁺-Chelating Mesoporous Silica Nanoparticles for Synergistic Chemotherapy/Chemodynamic Therapy

Pharmaceutics, 2022
In this study, a pH-responsive controlled-release mesoporous silica nanoparticle (MSN) formulation was developed. The MSNs were functionalized with a histidine (His)-tagged targeting peptide (B3int) through an amide bond, and loaded with an anticancer ...
Yanyan Zhang, Jiadong Lou, Gareth R. Williams, Yuhan Ye, Dandan Ren, Anhua Shi, Junzi Wu, Wenling Chen, Li-Min Zhu   +8 more
doaj   +1 more source

A Peptide-Based Trap for Metal Ions Studied by Electron Paramagnetic Resonance

Chemosensors, 2022
Peptide-based materials provide a versatile platform for sensing and ion sequestration since peptides are endowed with stimuli-responsive properties. The mechanism of molecular sensing is often based on peptide structural changes (or switching), caused ...
Victoria N. Syryamina, Alvaro S. Siano, Fernando Formaggio, Marta De Zotti   +3 more
doaj   +1 more source

Research Advances in Cadmium Uptake, Transport and Resistance in Rice (Oryza sativa L.)

Cells, 2022
Rice (Oryza sativa L.) is one of the most important food crops, feeding half of the world’s population. However, rice production is affected by cadmium (Cd) toxicity.
Jialiang Zhang, Yanchun Zhu, Lijuan Yu, Meng Yang, Xiao Zou, Changxi Yin, Yongjun Lin   +6 more
doaj   +1 more source

Novel Iron-Chelator DIBI Inhibits Staphylococcus aureus Growth, Suppresses Experimental MRSA Infection in Mice and Enhances the Activities of Diverse Antibiotics in vitro

Frontiers in Microbiology, 2018
DIBI, a purpose-designed hydroxypyridinone-containing iron-chelating antimicrobial polymer was studied for its anti-staphylococcal activities in vitro in comparison to deferiprone, the chemically related, small molecule hydroxypyridinone chelator.
Maria del Carmen Parquet, Kimberley A. Savage, David S. Allan, Ross J. Davidson, Ross J. Davidson, Bruce E. Holbein, Bruce E. Holbein   +6 more
doaj   +1 more source

How early can myocardial iron overload occur in Beta thalassemia major? [PDF]

, 2014
BACKGROUND: Myocardial siderosis is the most common cause of death in patients with beta thalassemia major(TM). This study aimed at investigating the occurrence, prevalence and severity of cardiac iron overload in a young Chinese population with beta TM.
A Aessopos, AM Maceira, AW Leung, B Modell, B Modell, B Modell, BA Davis, C Borgna-Pignatti, DH Fitchett, DJ Weatherall, DT Kremastinos, F Alpendurada, G Barosi, Gaohui Yang, GM Brittenham, GM Brittenham, HF Pan, Hongfei Pan, JC Wood, JC Wood, JC Wood, JL Fernandes, K Tziomalos, Liling Long, Lisa Anderson, LJ Anderson, LJ Anderson, M Angastiniotis, M Bejaoui, M Westwood, MA Aldouri, MA Tanner, MA Tanner, MA Tanner, MAEM Engle, NF Olivieri, P Kirk, Peng Peng, Q Meng, Rongrong Liu, Shaohong Tan, T He, Taigang He, V Positano, Weijia Yang, Xiaolei Xu, Xingjiang Long, Xinhua Zhang, Yong-rong Lai, Yongrong Lai   +49 more
core   +2 more sources

Iron Chelation in Local Infection

Molecules, 2021
Iron is an essential element in multiple biochemical pathways in humans and pathogens. As part of the innate immune response in local infection, iron availability is restricted locally in order to reduce overproduction of reactive oxygen species by the ...
Cassidy Scott, Gaurav Arora, Kayle Dickson, Christian Lehmann   +3 more
doaj   +1 more source