Results 11 to 20 of about 28,637 (186)

The Role of Iron Chelation Therapy in Colorectal Cancer: A Systematic Review on Its Mechanisms and Therapeutic Potential [PDF]

open access: yesCancer Medicine
Background Despite significant therapeutic advancements in recent decades, colorectal cancer (CRC) continues to exhibit high rates of mortality and morbidity.
Gihani Vidanapathirana   +4 more
doaj   +3 more sources

Endocrine Complications and the Effect of Compliance with Chelation Therapy in Patients with Beta Thalassemia Major in Eastern Province of Saudi Arabia [PDF]

open access: yesJournal of Blood Medicine, 2022
Fatema Habbash,* Wegdan Al-Bati,* Howra Al-Hashim,* Maryam Aldossari,* Ahmed Alali, Khalid Alalyani, Zainab Al-Ebrahim, Nouf Hamed, Samma Eraqe, Ziyad Binayfan, Azzam Al Marri, Thamer Aljaber Department of Family and Community Medicine ...
Habbash F   +11 more
doaj   +4 more sources

EDTA chelation therapy for cardiovascular disease: a systematic review [PDF]

open access: yesBMC Cardiovascular Disorders, 2005
Background Numerous practitioners of both conventional and complementary and alternative medicine throughout North America and Europe claim that chelation therapy with EDTA is an effective means to both control and treat cardiovascular disease.
Wu Ping, Seely Dugald MR, Mills Edward J
doaj   +5 more sources

Barriers to adherence to iron chelation therapy among adolescent with transfusion dependent thalassemia [PDF]

open access: yesFrontiers in Pediatrics, 2022
Study backgroundThalassemia is the commonest genetic blood disorder in Malaysia which requires life-long blood transfusions. From a total of 7,984 thalassemia patients in Malaysia, adolescent age group account for the highest number of patients (2,680 ...
Rafaa Mohamed   +3 more
doaj   +2 more sources

Advances in iron chelation therapy: transitioning to a new oral formulation [PDF]

open access: yesDrugs in Context, 2017
Iron overload is a concern for patients who require repeated red-blood-cell transfusions due to conditions such as sickle cell disease, thalassemia, or myelodysplastic syndromes.
Nirmish R Shah
doaj   +2 more sources

A MULTICENTER ICET-A STUDY ON AGE AT MENARCHE AND MENSTRUAL CYCLES IN PATIENTS WITH TRANSFUSION-DEPENDENT THALASSEMIA (TDT) WHO STARTED EARLY CHELATION THERAPY WITH DIFFERENT CHELATING AGENTS. [PDF]

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2023
. Objective: To evaluate the age at menarche and menstrual characteristics in patients with transfusion-dependent thalassemia (TDT) who started early chelation therapy (≤ 3 years) with a variety of chelating agents.
SALVATORE DI MAIO   +13 more
doaj   +2 more sources

Will Short Peptides Revolutionize Chelation Therapy? [PDF]

open access: yesCHIMIA, 2022
It will soon be twenty years since the last chelating agent was clinically approved to be used against toxic metals. Even though metal poisoning has been known to humankind for centuries, only about a dozen compounds, all of which are small molecules ...
Michal S. Shoshan
doaj   +3 more sources

Predictors of Non-adherence to iron chelation therapy in pediatric thalassemia patients [PDF]

open access: yesJournal of Rawalpindi Medical College, 2022
Objective: This study was conducted to identify predictors of non-adherence to iron chelation therapy among children suffering from β-thalassemia major across different treatment regimens.
Muniba Kanwal   +3 more
doaj   +3 more sources

Iron Chelation Therapy in Myelodysplastic Syndromes [PDF]

open access: yesAdvances in Hematology, 2010
Myelodysplastic syndromes (MDS) are a heterogeneous disorder of the hematopoietic stem cells, frequently characterized by anemia and transfusion dependency. In low-risk patients, transfusion dependency can be long lasting, leading to iron overload.
Emanuela Messa   +2 more
doaj   +2 more sources

Challenges of Iron Chelation in Thalassemic Children [PDF]

open access: yesThalassemia Reports
Thalassemia treatment still relies on supportive care, mainly including blood transfusion and iron chelation therapy. Iron chelation is considered the main factor responsible for the marked improvement in survival rates of thalassemic patients ...
Alkistis Adramerina, Marina Economou
doaj   +2 more sources

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