Results 31 to 40 of about 28,637 (186)
Chelation therapy after the Trial to Assess Chelation Therapy [PDF]
Current Opinion in Cardiology, 2014 EDTA chelation therapy has been in off-label use for the treatment of atherosclerosis. We review the results of the first large-scale randomized trial of this treatment.The trial to assess chelation therapy was a $30 million National Institutes of Health-funded study of the safety and efficacy of EDTA-based chelation infusions in 1708 post-myocardial ...
Avila, Maria D. +2 more
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Annals of the New York Academy of Sciences, 2023 Abstract Combination chelation therapies are considered in transfusion‐dependent thalassemia patients for whom monotherapy regimens have failed to achieve iron balance or intensification of iron chelation therapy is required for the rapid reduction of excess iron to avoid permanent organ damage.
openaire +2 more sources
Chelator-facilitated removal of iron from transferrin: Relevance to combined chelation therapy [PDF]
, 2007 Current iron chelation therapy consists primarily of DFO (desferrioxamine), which has to be administered via intravenous infusion, together with deferiprone and deferasirox, which are orally-active chelators.
Hider, Robert C +11 more
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Медицинский совет, 2016 Iron overload (RV) is a condition caused by excessive intake of iron, and in the absence of the specific mechanisms for its excretion - excessive accumulation in tissues and their subsequent lesion leading to functional organ failure [1].
M. V. Krasolnikova
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Assessment of Thalassemic Children Knowledge about Thalassemia and Iron Chelation Therapy [PDF]
Port Said Scientific Journal of Nursing, 2019 Background: Thalassemia is a major inherited public health problem in the Mediterranean area. Aim of this study was to assess children knowledge about thalassemia and iron chelation therapy. Subjects and methods: A descriptive research design was used. A
Rehab Hanie El-Kazaz +3 more
doaj +1 more source
Overview of chelation recommendations for thalassaemia and sickle cell disease
Thalassemia Reports, 2014 The long term consequences of iron toxicity are mostly reversible with effective iron chelation therapy. Recommendations for use of chelation therapy in transfusion dependent thalassaemia (TDT), sickle cell disease (SCD) and non transfusion dependent ...
Banu Kaya
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Alarming use of chelation therapy [PDF]
, 2014 Chelation therapy is a consolidated medical procedure used primarily to hinder the effects of toxic metal ions on human tissues. Its application spans a broad spectrum of disorders, ranging from acute metal intoxication to genetic metal-overload. The use
Nurchi, Valeria Marina +5 more
core +5 more sources
Iron Chelation Therapy in COVID-19 Infection
Southeastern European Medical Journal, 2022 The recent outbreak of corona virus and coronavirus disease (COVID-19) caused by the SARS-CoV-2 virus is a global concern. Despite efforts to clarify the physiology and potential therapy, specific guidelines for the treatment of COVID-19 disease have yet
Irena Krajina Kmoniček +2 more
doaj +1 more source
Importance of iron chelation therapy
Thalassemia Reports, 2011 It is necessary to remember that today patients have different options of chelation treatment, as desferrioxamine, deferiprone and deferasirox are available. However, a patient has to be compliant with treatments.
A. Varoğlu
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Effect of Chelation Therapy on a Korean Patient With Brain Manganese Deposition Resulting From a Compound Heterozygous Mutation in the SLC39A14 Gene [PDF]
Journal of Movement Disorders, 2022 Mutations in the manganese transporter gene SLC39A14 lead to inherited disorders of manganese metabolism. Chelation therapy with edetate calcium disodium (SLC39A14 deficiencyTA) is known to effectively reduce manganese deposition.
Jae-Hyeok Lee, Jin-Hong Shin
doaj +1 more source