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Alarming use of chelation therapy [PDF]

, 2014
Chelation therapy is a consolidated medical procedure used primarily to hinder the effects of toxic metal ions on human tissues. Its application spans a broad spectrum of disorders, ranging from acute metal intoxication to genetic metal-overload. The use
Nurchi, Valeria Marina, Lachowicz, Joanna I., Peana, Massimiliano Francesco, Crespo-Alonso, Miriam, Crisponi, Guido, Zoroddu, Maria Antonietta   +5 more
core   +3 more sources

Red Blood Cell Transfusion Independence Following the Initiation of Iron Chelation Therapy in Myelodysplastic Syndrome

Advances in Hematology, 2010
Iron chelation therapy is often used to treat iron overload in patients requiring transfusion of red blood cells (RBC). A 76-year-old man with MDS type refractory cytopenia with multilineage dysplasia, intermediate-1 IPSS risk, was referred when he ...
Maha A. Badawi, Linda M. Vickars, Jocelyn M. Chase, Heather A. Leitch   +3 more
doaj   +1 more source

Healthcare resource utilization and direct costs of transfusion-dependent thalassemia patients in Dubai, United Arab Emirates: a retrospective cost-of-illness study

BMC Health Services Research, 2022
Background Patients with transfusion-dependent thalassemia (TDT) require lifelong blood transfusions and iron chelation therapy. Thus, patients afflicted with TDT often have to undergo blood transfusion and iron chelation therapy, which causes a major ...
Shaikha Alshamsi, Samer Hamidi, Hacer Ozgen Narci   +2 more
doaj   +1 more source

Knowledge, Attitude, and Practice of Young Paediatricians About Chelation Therapyin Transfusion-Dependent Thalassemia Major Children

Pakistan Armed Forces Medical Journal, 2022
Objective: To determine the knowledge, attitude, and practice of young paediatricians about chelation therapy in transfusiondependent thalassemia major children.
Misbah Fakih, Faisal Basheer, Saad Ateeq, Farooq Ikram, Hafsa Asad, Qamar uz Zaman Khan   +5 more
doaj   +1 more source

Beliefs about chelation among thalassemia patients

Health and Quality of Life Outcomes, 2012
Background Understanding patients’ views about medication is crucial to maximize adherence. Thalassemia is a congenital blood disorder requiring chronic blood transfusions and daily iron chelation therapy.
Trachtenberg Felicia L, Mednick Lauren, Kwiatkowski Janet L, Neufeld Ellis J, Haines Dru, Pakbaz Zahra, Thompson Alexis A, Quinn Charles T, Grady Robert, Sobota Amy, Olivieri Nancy, Horne Robert, Yamashita Robert   +12 more
doaj   +1 more source

Pubertal Development in Girls with Beta Thalassaemia and Assessment of the Adequacy of Chelation Therapy: A Quasi-experimental Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Beta thalassaemia is the most prevalent hereditary autosomal disorder, significantly impacting endocrine function during pubertal development. The pathology is rooted in the excessive deposition of iron in vital organs.
Rupali Modak, Amitava Pal, Shuvendu Das, Dilip Kumar Biswas   +3 more
doaj   +1 more source

MYELODYSPLASTIC SYNDROMES AND IRON CHELATION THERAPY

Mediterranean Journal of Hematology and Infectious Diseases, 2017
Over recent decades we have been fortunate to witness the advent of new technologies and of an expanded knowledge and application of chelation therapies to the benefit of patients with iron overload.
Emanuele Angelucci, Silvana Anna Maria Urru, Federica Pilo, Alberto Piperno   +3 more
doaj   +1 more source

Challenges of Iron Chelation in Thalassemic Children

Thalassemia Reports
Thalassemia treatment still relies on supportive care, mainly including blood transfusion and iron chelation therapy. Iron chelation is considered the main factor responsible for the marked improvement in survival rates of thalassemic patients ...
Alkistis Adramerina, Marina Economou
doaj   +1 more source

IRON CHELATION THERAPY IN THALASSEMIA SYNDROMES

Mediterranean Journal of Hematology and Infectious Diseases, 2009
Transfusional hemosiderosis is a frequent complication in patients with transfusion dependent chronic diseases such as  thalassemias and severe type of sickle cell diseases.
Paolo Cianciulli
doaj   +1 more source

Warns against unapproved 'chelation therapy'

, 2014
At Eurobic11 in Granada we presented a Keynote Lecture on chelation therapy, a consolidated medical procedure used primarily to hinder the effects of toxic metal ions on human tissues.
PEANA, Massimiliano Francesco, Nurchi, Valeria Marina, Lachowicz, Joanna I., ZORODDU, Maria Antonietta, Crisponi, Guido, Crespo Alonso, Miriam   +5 more
core   +2 more sources