Results 51 to 60 of about 28,637 (186)

IRON CHELATION THERAPY IN THALASSEMIA SYNDROMES

Mediterranean Journal of Hematology and Infectious Diseases, 2009
Transfusional hemosiderosis is a frequent complication in patients with transfusion dependent chronic diseases such as  thalassemias and severe type of sickle cell diseases.
Paolo Cianciulli
doaj   +1 more source

Iron chelation therapy in transfusion-dependent thalassemia patients: current strategies and future directions [PDF]

, 2015
Antoine N Saliba, Afif R Harb, Ali T Taher Department of Internal Medicine, Division of Hematology/Oncology, American University of Beirut, Beirut, Lebanon Abstract: Transfusional iron overload is a major target in the care of patients with transfusion ...
Taher AT, Saliba AN, Harb AR
core  

Machine learning in the prediction of liver iron concentration and iron chelation therapy adjustment

Hematology
Objectives Iron chelation therapy titration is managed by hematologists who monitor iron levels and adjust medication dosages to achieve patient outcomes. This study developed a machine learning (ML) algorithm to predict the liver iron concentration (LIC)
Joanna Bao-Ern Loh, Sangwook Kim, Richard Ward, Soodeh Sagheb, Andrew Binding, Kevin H.M. Kuo, Chris McIntosh, Kartik Jhaveri   +7 more
doaj   +1 more source

Randomised trial of chelation therapy. [PDF]

, 1995
Randomised trial of chelation ...
BA Swinburn (14393667)
core  

Effect of Combined Hydroxyurea and Chelation Therapy in Reducing Serum Ferritin Level, Liver and Spleen Size in Transfusion Dependent Thalassaemia Major Patients.

Journal of Rawalpindi Medical College, 2019
Background: To compare hydroxyurea plus iron chelation therapy with iron chelation therapy alone in controlling iron overload in children with beta thalassaemia major.
Tatheer Zahra, Wajeeha Amber, Itrat Fatima   +2 more
doaj  

Changes in inflammatory cytokines, antioxidants and liver stiffness after chelation therapy in individuals with chronic lead poisoning

BMC Gastroenterology, 2020
Background Chronic exposure to lead causes lead to accumulate mainly in the liver. In vivo studies have shown that lead toxicity is related to alterations in the inflammatory response. We aimed to evaluate the association between lead poisoning and liver
Tongluk Teerasarntipan, Roongruedee Chaiteerakij, Piyapan Prueksapanich, Duangporn Werawatganon   +3 more
doaj   +1 more source

Erythrocytapheresis as a strategy to manage anemia and iron overload in nondeletional hemoglobin H disease

eJHaem
Hemoglobin H (HbH) disease is associated with anemia, ineffective erythropoiesis, and iron overload. We report a case of a patient with HbH/Hb Constant Spring disease, who was maintained on chronic transfusions as an adult due to symptomatic anemia. Over
Ke Zhang, John Bliamptis, Janice Park, Patricia Kopko, Amber P. Sanchez, Srila Gopal   +5 more
doaj   +1 more source

Lead toxicosis of captive vultures: case description and responses to chelation therapy

BMC Veterinary Research, 2013
Background Lead, a serious threat for raptors, can hamper the success of their conservation. This study reports on experience with accidental lead intoxication and responses to chelation therapy in captive Cinereous (Aegypius monachus) and Egyptian ...
Pikula Jiri, Hajkova Pavlina, Bandouchova Hana, Bednarova Ivana, Adam Vojtech, Beklova Miroslava, Kral Jiri, Ondracek Karel, Osickova Jitka, Pohanka Miroslav, Sedlackova Jana, Skochova Hana, Sobotka Jakub, Treml Frantisek, Kizek Rene   +14 more
doaj   +1 more source

Chelation therapy to prevent diabetes-associated cardiovascular events [PDF]

, 2018
Purpose of review For over 60 years, chelation therapy with disodium ethylene diamine tetraacetic acid (EDTA, edetate) had been used for the treatment of cardiovascular disease (CVD) despite lack of scientific evidence for efficacy and safety.
Fonseca, Vivian, Aude, Y. Wady, Lamas, Gervasio A., Yamil W. Aude, Vivian Fonseca, Diaz, Denisse, Denisse Diaz, Gervasio A. Lamas   +7 more
core   +2 more sources

2D-ultrathin MXene/DOXjade platform for iron chelation chemo-photothermal therapy

Bioactive Materials, 2022
An increased demand for iron is a hallmark of cancer cells and is thought necessary to promote high cell proliferation, tumor progression and metastasis. This makes iron metabolism an attractive therapeutic target.
Yunjie Xu, Yingwei Wang, Jusung An, Adam C. Sedgwick, Mingle Li, Jianlei Xie, Weibin Hu, Jianlong Kang, Sajal Sen, Axel Steinbrueck, Bin Zhang, Lijun Qiao, Swelm Wageh, Jonathan F. Arambula, Liping Liu, Han Zhang, Jonathan L. Sessler, Jong Seung Kim   +17 more
doaj   +1 more source