Results 281 to 290 of about 218,507 (292)

Comprehensive Overview of Carboxamide Derivatives as Succinate Dehydrogenase Inhibitors.

Journal of Agricultural and Food Chemistry, 2022
Up to now, a total of 24 succinate dehydrogenase inhibitors (SDHIs) fungicides have been commercialized, and SDHIs fungicides were also one of the most active fungicides developed in recent years. Carboxamide derivatives represented an important class of
B. Luo, Yuli Ning
semanticscholar   +1 more source

Gut microbiota-derived succinate aggravates acute lung injury after intestinal ischaemia/reperfusion in mice

European Respiratory Journal, 2022
Introduction Acute lung injury (ALI) is a major cause of morbidity and mortality after intestinal ischaemia/reperfusion (I/R). The gut microbiota and its metabolic byproducts act as important modulators of the gut–lung axis.
Yi-Heng Wang, Zhengzheng Yan, Sihan Luo, Jingjuan Hu, Mei Wu, Jin Zhao, Wei-Feng Liu, Cai Li, Ke-xuan Liu   +8 more
semanticscholar   +1 more source

Untargeted metabolomics identifies succinate as a biomarker and therapeutic target in aortic aneurysm and dissection.

European Heart Journal, 2021
AIMS Aortic aneurysm and dissection (AAD) are high-risk cardiovascular diseases with no effective cure. Macrophages play an important role in the development of AAD.
Hongtu Cui, Yanghui Chen, Ke Li, Rui Zhan, Mingming Zhao, Yangkai Xu, Zhiyong Lin, Yi Fu, Qi-hua He, P. Tang, Ienglam Lei, Jifeng Zhang, Chenze Li, Yang Sun, Xinhua Zhang, T. Horng, Hong S. Lu, Y. E. Chen, A. Daugherty, Daowen Wang, Lemin Zheng   +20 more
semanticscholar   +1 more source

Host succinate is an activation signal for Salmonella virulence during intracellular infection

Science, 2021
Salmonella profits from immunometabolism Extensive metabolic rewiring occurs in various immune cells during the course of infection. Whether these changes can be exploited by intracellular pathogens remains an open question. Rosenberg et al.
G. Rosenberg, D. Yehezkel, Dotan Hoffman, C. Mattioli, Moran Fremder, Hadar Ben-Arosh, Leia Vainman, Noa Nissani, Shelly Hen-Avivi, Shirley Brenner, M. Itkin, S. Malitsky, Ehud Ohana, N. B. Ben-Moshe, R. Avraham   +14 more
semanticscholar   +1 more source

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase.

Cancer Cell, 2005
M. Selak, S. Armour, Elaine D. MacKenzie, Houda Boulahbel, D. G. Watson, K. Mansfield, Yi Pan, M. Simon, C. Thompson, E. Gottlieb   +9 more
semanticscholar   +1 more source

HIF1α/ATF3 partake PGK1 K191/K192 succinylation by modulating P4HA1/succinate signaling in glioblastoma.

Neuro-Oncology
Shixue Yang, Zhan Qi, Dongyuan Su, Xiaoteng Cui, Jixing Zhao, Wang Qixue, Hong Biao, Jiasheng Ju, Chunchao Cheng, Yang Eryan, Chunsheng Kang   +10 more
semanticscholar   +1 more source