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Development of a Well-Characterized Cynomolgus Macaque Model of Sudan Virus Disease for Support of Product Development [PDF]

open access: yesVaccines, 2022
The primary objective of this study was to characterize the disease course in cynomolgus macaques exposed to Sudan virus (SUDV), to determine if infection in this species is an appropriate model for the evaluation of filovirus countermeasures under the ...
Kendra J. Alfson   +18 more
doaj   +6 more sources

Sudan virus disease super-spreading, Uganda, 2022 [PDF]

open access: yesBMC Infectious Diseases, 2023
Background On 20 September 2022, Uganda declared its fifth Sudan virus disease (SVD) outbreak, culminating in 142 confirmed and 22 probable cases. The reproductive rate (R) of this outbreak was 1.25.
Allan Komakech   +82 more
doaj   +4 more sources

Recombinant Sudan virus and evaluation of humoral cross-reactivity between Ebola and Sudan virus glycoproteins after infection or rVSV-ΔG-ZEBOV-GP vaccination

open access: yesEmerging Microbes and Infections, 2023
Ebola disease outbreaks are major public health events because of human-to-human transmission and high mortality. These outbreaks are most often caused by Ebola virus, but at least three related viruses can also cause the disease. In 2022, Sudan virus re-
Markus H. Kainulainen   +11 more
doaj   +5 more sources

Molecular characterization of the 2022 Sudan virus disease outbreak in Uganda [PDF]

open access: yesJournal of Virology, 2023
ABSTRACT Uganda experienced five Ebola disease outbreaks caused by Bundibugyo virus ( n = 1) and Sudan virus (SUDV) ( n = 4) from 2000 to 2021.
Stephen Balinandi   +28 more
exaly   +5 more sources

Sudan virus disease outbreak in Uganda: urgent research gaps [PDF]

open access: yesBMJ Global Health, 2022
The Sudan ebolavirus (SUDV) outbreak highlights our ongoing vulnerability to re-emerging high-consequence infectious diseases. Although the Minister of health in Uganda has initiated public health measures in collaboration with neighbouring countries and
Duduzile Edith Ndwandwe   +3 more
doaj   +5 more sources

Sudan virus disease outbreak in Uganda in 2022: the case of patient zero

open access: yesInternational Journal of Infectious Diseases, 2023
: In 2000, Uganda reported the first Ebola disease outbreak, and since then, the nation has had several other outbreaks. Case presentation: On September 15, 2022, a Ugandan man aged 24 years presented with a history of fever, hematemesis, and ...
Phillip Musoke, Felix Bongomin
doaj   +5 more sources

Sudan virus disease – A quick review

open access: yesJournal of the Formosan Medical Association
The recent Sudan virus disease (SVD) outbreak in Uganda is a reminder of threat from Filovirus diseases. Unlike Ebola virus disease, no effective antiviral and vaccine is available for SVD.
Tsung-Pei Tsou
doaj   +5 more sources

Multiple Crimean-Congo hemorrhagic fever virus strains are associated with disease outbreaks in Sudan, 2008-2009. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2011
BACKGROUND: Crimean-Congo hemorrhagic fever (CCHF) activity has recently been detected in the Kordufan region of Sudan. Since 2008, several sporadic cases and nosocomial outbreaks associated with high case-fatality have been reported in villages and ...
Imadeldin E Aradaib   +6 more
doaj   +4 more sources

Association of genotype III of dengue virus serotype 3 with disease outbreak in Eastern Sudan, 2019 [PDF]

open access: yesVirology Journal, 2020
Background Dengue fever (DF) is an arthropod-borne disease caused by dengue virus (DENV). DENV is a member of the genus Flavivirus in the family Flaviviridae.
Mawahib H. Eldigail   +8 more
doaj   +3 more sources

Resurgence of Sudan Virus Disease (SUVD) in Uganda

open access: yesGlobal Biosecurity, 2022
On September 20th, 2022, a case of ebola virus disease was confirmed in Uganda by the World Health Organization. The presumed index case of a 24-year-old male was sequenced and identified as the Sudan strain. This was the first known outbreak of ebola in
Damian Alexander Honeyman   +1 more
doaj   +3 more sources

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