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Pathogens, 2022 Intravenous (IV) administration of antiviral monoclonal antibodies (mAbs) can be challenging, particularly during an ongoing epidemic, due to the considerable resources required for performing infusions.
Robert W Cross +2 more
exaly +6 more sources
Ebolavirus Replication and Tetherin/BST-2 [PDF]
Frontiers in Microbiology, 2012 Ebolavirus (EBOV) is an enveloped, non-segmented, negative-stranded RNA virus, which consists of five species: Zaire ebolavirus (ZEBOV), Sudan ebolavirus (SEBOV), Tai Forest ebolavirus (TFEBOV), Bundibugyo ebolavirus (BEBOV), and Reston ebolavirus (REBOV)
Jiro Yasuda
exaly +7 more sources
Ebolavirus Δ-Peptide Immunoadhesins Inhibit Marburgvirus and Ebolavirus Cell Entry [PDF]
Journal of Virology, 2011 With the exception of Reston and Lloviu viruses, filoviruses (marburgviruses, ebolaviruses, and “cuevaviruses”) cause severe viral hemorrhagic fevers in humans.
Peter B. Jahrling +18 more
core +3 more sources
Assembly and budding of Ebolavirus. [PDF]
PLoS Pathogens, 2006 Ebolavirus is responsible for highly lethal hemorrhagic fever. Like all viruses, it must reproduce its various components and assemble them in cells in order to reproduce infectious virions and perpetuate itself.
Muramoto Yukiko +19 more
core +5 more sources
Ebolavirus is internalized into host cells via macropinocytosis in a viral glycoprotein-dependent manner. [PDF]
PLoS Pathogens, 2010 Ebolavirus (EBOV) is an enveloped, single-stranded, negative-sense RNA virus that causes severe hemorrhagic fever with mortality rates of up to 90% in humans and nonhuman primates.
Asuka Nanbo +7 more
doaj +3 more sources
Serological evidence of ebolavirus infection in bats, China
Virology Journal, 2012 Background The genus Ebolavirus of the family Filoviridae currently consists of five species. All species, with the exception of Reston ebolavirus, have been found in Africa and caused severe human diseases.
Yuan Junfa +5 more
doaj +2 more sources
Tracking ebolavirus genomic drift with a resequencing microarray.
PLoS ONE, 2022 Filoviruses are emerging pathogens that cause acute fever with high fatality rate and present a global public health threat. During the 2013-2016 Ebola virus outbreak, genome sequencing allowed the study of virus evolution, mutations affecting ...
Irina Tiper +7 more
doaj +2 more sources
Frontiers in Immunology, 2022 Monoclonal antibodies (mAbs) have proven effective for the treatment of ebolavirus infection in humans, with two mAb-based drugs Inmazeb™ and Ebanga™ receiving FDA approval in 2020.
Andrew Ward +2 more
exaly +3 more sources
Ebolavirus comparative genomics [PDF]
FEMS Microbiology Reviews, 2015 The 2014 Ebola outbreak in West Africa is the largest documented for this virus. To examine the dynamics of this genome, we compare more than 100 currently available ebolavirus genomes to each other and to other viral genomes. Based on oligomer frequency
Leuze, Michael R. +16 more
core +5 more sources
Bombali Ebolavirus in Mops condylurus Bats (Molossidae), Mozambique
Emerging Infectious Diseases, 2022 We detected Bombali ebolavirus RNA in 3 free-tailed bats (Mops condylurus, Molossidae) in Mozambique. Sequencing of the large protein gene revealed 98% identity with viruses previously detected in Sierra Leone, Kenya, and Guinea.
Camille Lebarbenchon +9 more
doaj +2 more sources