A Chimeric Sudan Virus-Like Particle Vaccine Candidate Produced by a Recombinant Baculovirus System Induces Specific Immune Responses in Mice and Horses [PDF]
Viruses, 2020 Ebola virus infections lead to severe hemorrhagic fevers in humans and nonhuman primates; and human fatality rates are as high as 67%−90%. Since the Ebola virus was discovered in 1976, the only available treatments have been medical support or the ...
Fangfang Wu +13 more
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Development of a Well-Characterized Cynomolgus Macaque Model of Sudan Virus Disease for Support of Product Development [PDF]
Vaccines, 2022 The primary objective of this study was to characterize the disease course in cynomolgus macaques exposed to Sudan virus (SUDV), to determine if infection in this species is an appropriate model for the evaluation of filovirus countermeasures under the ...
Kendra J. Alfson +18 more
doaj +4 more sources
Recombinant Sudan virus and evaluation of humoral cross-reactivity between Ebola and Sudan virus glycoproteins after infection or rVSV-ΔG-ZEBOV-GP vaccination [PDF]
Emerging Microbes and Infections, 2023 Ebola disease outbreaks are major public health events because of human-to-human transmission and high mortality. These outbreaks are most often caused by Ebola virus, but at least three related viruses can also cause the disease. In 2022, Sudan virus re-
Markus H. Kainulainen +11 more
doaj +2 more sources
Multiple Crimean-Congo hemorrhagic fever virus strains are associated with disease outbreaks in Sudan, 2008-2009. [PDF]
PLoS Neglected Tropical Diseases, 2011 BACKGROUND: Crimean-Congo hemorrhagic fever (CCHF) activity has recently been detected in the Kordufan region of Sudan. Since 2008, several sporadic cases and nosocomial outbreaks associated with high case-fatality have been reported in villages and ...
Imadeldin E Aradaib +6 more
doaj +3 more sources
Investigating the Sudan virus outbreak in Uganda through the deployment of a mobile laboratory [PDF]
BMC Infectious DiseasesBackground Uganda faced its sixth reported Ebola outbreak between September 2022 and January 2023, the fifth to be recorded as Sudan Virus Disease (SVD) in the country.
Godfrey Pimundu +26 more
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Serological Evidence of Zika Virus Infections in Sudan
VirusesLittle is known about the frequency of Zika virus (ZIKV) infections in Sudan. The aim of this study was to obtain data on the prevalence of ZIKV infections and the immunity of the population in the country. To this end, 198 sera obtained between December
Awadalkareem Adam +4 more
doaj +3 more sources
Molecular characterization of the 2022 Sudan virus disease outbreak in Uganda [PDF]
Journal of Virology, 2023 Julie Harris +2 more
exaly +2 more sources
Protection against Marburg Virus and Sudan Virus in NHP by an Adenovector-Based Trivalent Vaccine Regimen Is Correlated to Humoral Immune Response Levels [PDF]
Vaccines, 2022 Hanneke Schuitemaker +2 more
exaly +2 more sources
Development of an antibody cocktail for treatment of Sudan virus infection [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2020 , John Dye, Anna Wec
exaly +2 more sources
Pathogenicity and Virulence of Ebolaviruses with Species- and Variant-specificity
Virulence, 2021 Ebola virus (EBOV), belonging to the species Zaire ebolavirus in the genus Ebolavirus, causes a severe febrile illness in humans with case fatality rates (CFRs) up to 90%.
Satoko Yamaoka, Hideki Ebihara
doaj +1 more source