Results 21 to 30 of about 1,215,071 (208)
Development of a Crystallographic Screening to Identify Sudan Virus VP40 Ligands. [PDF]
ACS OmegaThe matrix protein VP40 of the highly pathogenic Sudan virus (genus Orthoebolavirus) is a multifunctional protein responsible for the recruitment of viral nucleocapsids to the plasma membrane and the budding of infectious virions. In addition to its role in assembly, VP40 also downregulates viral genome replication and transcription.
Werner AD +6 more
europepmc +5 more sources
An Antibody Cocktail Combats The Deadly Ebola Virus And Sudan Virus
TheScienceBreaker, 2023 There are several deadly viruses in the ebola virus family, but current antibody treatments are effective against only one. Our work discovered two antibodies from human survivors, and their benefit when combined together in a cocktail, to provide broader protection at a lower dose. We reveal surprising findings of how they act to achieve protection.
Xiaoying Yu, Erica Ollmann Saphire
openaire +1 more source
Phylogenetic and Ecologic Perspectives of a Monkeypox Outbreak, Southern Sudan, 2005
Emerging Infectious Diseases, 2013 Identification of human monkeypox cases during 2005 in southern Sudan (now South Sudan) raised several questions about the natural history of monkeypox virus (MPXV) in Africa. The outbreak area, characterized by seasonally dry riverine grasslands, is not
Yoshinori Nakazawa +21 more
doaj +1 more source
The Pan African Medical Journal, 2020 Corona Virus Disease (COVID-19) is caused by severe acute respiratory coronavirus type 2 (SARS-CoV-2), which was first reported in Wuhan, China [1,2].
David Majuch Kunjok +1 more
doaj +1 more source
Development and Characterization of a Guinea Pig-Adapted Sudan Virus [PDF]
Journal of Virology, 2016 ABSTRACT Infections with Sudan virus (SUDV), a member of the genus Ebolavirus , result in a severe hemorrhagic fever with a fatal outcome in over 50% of human cases. The paucity of prophylactics and therapeutics against SUDV is attributed to the lack of a small-animal model to screen promising compounds ...
Gary, Wong +11 more
openaire +2 more sources
Overt and occult hepatitis B virus infection in adult Sudanese HIV patients
International Journal of Infectious Diseases, 2014 Objectives: Human immunodeficiency virus (HIV) infection in Sub-Saharan Africa is complicated by co-infection with hepatitis B and C viruses (HBV and HCV), which share similar transmission routes.
Hatim Mudawi +6 more
doaj +1 more source
Investigation of caprine arthritis-encephalitis virus in Sudan using competitive enzyme-linked immunosorbent assay [PDF]
Veterinary World, 2013 Aim: This seroprevalence study was carried out to detect anti Caprine Arthritis-Encephalitis Virus (CAEV) antibodies in goat sera in five States in the Sudan during 2009 and 2010.
Rajaa H. Halfawi +6 more
doaj +1 more source
A Serological Survey of Akabane Virus Infection in Cattle in Sudan [PDF]
ISRN Veterinary Science, 2014 A cross-sectional survey was carried out in ten states in Sudan to determine seroprevalence and to assess risk factors associated with Akabane virus (AKAV) infection in dairy herds. Serum samples were collected from a total of 361 dairy cattle and tested for antibodies against AKAV using ELISA.
Elhassan, Amira M. +3 more
openaire +2 more sources
Structural Basis for Differential Neutralization of Ebolaviruses
Viruses, 2012 There are five antigenically distinct ebolaviruses that cause hemorrhagic fever in humans or non-human primates (Ebola virus, Sudan virus, Reston virus, Taï Forest virus, and Bundibugyo virus).
John M. Dye +11 more
doaj +1 more source
Human Vaccines & Immunotherapeutics, 2017 Immunoinformatics tools were used to predict human leukocyte antigen (HLA) class II-restricted T cell epitopes within the envelope glycoproteins and nucleocapsid proteins of Ebola virus (EBOV) and Sudan virus (SUDV) and the structural proteins of ...
Callie E. Bounds +8 more
doaj +1 more source