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Ebolavirus and Other Filoviruses [PDF]

, 2007
(Uploaded by Plazi for the Bat Literature Project) Since Ebola fever emerged in Central Africa in 1976, a number of studies have been undertaken to investigate its natural history and to characterize its transmission from a hypothetical reservoir host(s) to humans.
Leroy, E., Gonzalez, J. P., Pourrut, X.
openaire   +3 more sources

Traits, phylogeny and host cell receptors predict Ebolavirus host status among African mammals.

PLoS Neglected Tropical Diseases, 2022
We explore how animal host traits, phylogenetic identity and cell receptor sequences relate to infection status and mortality from ebolaviruses. We gathered exhaustive databases of mortality from Ebolavirus after exposure and infection status based on ...
Mekala Sundaram, John Paul Schmidt, Barbara A Han, John M Drake, Patrick R Stephens   +4 more
doaj   +1 more source

Increasing Occurrence of Marburg Virus Outbreaks in Africa: Risk Assessment for Public Health. [PDF]

Microb Biotechnol
Bat and Marburg virus (Filovirus). Left: A Rousettus aegyptiacus bat; Center: a distribution map of R. aegyptiacus; Right: EM of Marburg virus. (figure credits: Left Wikipedia Nilflughund Lithuanian Zoological Gardens, Center; Center: Wikipedia Nilflughund IUCN Red List of Threatened Species, right Wikipedia Marburg virus CDC Fred Murphy; J.
Brüssow H.
europepmc   +2 more sources

Ebolavirus: Pseudotypes, Libraries and Standards [PDF]

Future Virology, 2015
Globalization, accompanied by increasing levels of international travel and trade, climate change, altered human behavior and demographics, is leading to the emergence of manifold viral diseases, many of which are highly pathogenic and hence are considered of great public and animal health importance to the global populace [1].
Temperton, Nigel J., Page, Mark
openaire   +2 more sources

Serological evidence of ebolavirus infection in bats, China

Virology Journal, 2012
Background The genus Ebolavirus of the family Filoviridae currently consists of five species. All species, with the exception of Reston ebolavirus, have been found in Africa and caused severe human diseases.
Yuan Junfa, Zhang Yuji, Li Jialu, Zhang Yunzhi, Wang Lin-Fa, Shi Zhengli   +5 more
doaj   +1 more source

Ebolavirus vaccines for humans and apes [PDF]

Current Opinion in Virology, 2012
Because of high case fatality proportions, person-to-person transmission, and potential use in bioterrorism, the development of a vaccine against ebolavirus remains a top priority. Although no licensed vaccine or treatment against ebolavirus is currently available, progress in preclinical testing of countermeasures has been made.
Hugues, Fausther-Bovendo, Sabue, Mulangu, Nancy J, Sullivan   +2 more
openaire   +2 more sources

Epitope-based peptide vaccine against Bombali Ebolavirus viral protein 40: An immunoinformatics combined with molecular docking studies

Informatics in Medicine Unlocked, 2021
Bombali Ebolavirus belongs to the RNA group of viruses which causes lethal hemorrhagic fever with a high mortality rate. Despite these facts, yet there is no approved vaccine have been developed for the eradication of Bombali Ebolavirus infections ...
Mujahed I. Mustafa, Shaza W. Shantier, Miyssa I. Abdelmageed, Abdelrafie M. Makhawi   +3 more
doaj   +1 more source

Bombali Ebolavirus in Mops condylurus Bats (Molossidae), Mozambique

Emerging Infectious Diseases, 2022
We detected Bombali ebolavirus RNA in 3 free-tailed bats (Mops condylurus, Molossidae) in Mozambique. Sequencing of the large protein gene revealed 98% identity with viruses previously detected in Sierra Leone, Kenya, and Guinea.
Camille Lebarbenchon, Steven M. Goodman, Axel O.G. Hoarau, Gildas Le Minter, Andréa Dos Santos, M. Corrie Schoeman, Christophe Léculier, Hervé Raoul, Eduardo S. Gudo, Patrick Mavingui   +9 more
doaj   +1 more source

Assembly and Budding of Ebolavirus

PLoS Pathogens, 2006
Ebolavirus is responsible for highly lethal hemorrhagic fever. Like all viruses, it must reproduce its various components and assemble them in cells in order to reproduce infectious virions and perpetuate itself. To generate infectious Ebolavirus, a viral genome-protein complex called the nucleocapsid (NC) must be produced and transported to the cell ...
Takeshi Noda, Hideki Ebihara, Yukiko Muramoto, Ken Fujii, Ayato Takada, Hiroshi Sagara, Jin Hyun Kim, Hiroshi Kida, Heinz Feldmann, Yoshihiro Kawaoka   +9 more
openaire   +4 more sources

Ebolavirus and Haemorrhagic Syndrome

Sultan Qaboos University Medical Journal, 2015
The Ebola virus is a highly virulent, single-stranded ribonucleic acid virus which affects both humans and apes and has fast become one of the world's most feared pathogens. The virus induces acute fever and death, with haemorrhagic syndrome occurring in up to 90% of patients.
Gerald A. Matua, Dirk M. Van der Wal, Rozzano C. Locsin   +2 more
openaire   +4 more sources