Results 21 to 30 of about 8,175 (207)
Ebolavirus and Marburgvirus: insight the Filoviridae family [PDF]
Molecular Aspects of Medicine, 2008 Ebolavirus and Marburgvirus (belonging to the Filoviridae family) emerged four decades ago and cause epidemics of haemorrhagic fever with high case-fatality rates. The genome of filoviruses encodes seven proteins.
M. Bolognesi +15 more
core +9 more sources
Systemic and Mucosal Immune Responses From Serotype-Switched Viral-Vectored Ebola Vaccines. [PDF]
J Med VirolABSTRACT Ebola virus is a highly virulent pathogen causing severe hemorrhagic fever with 25%–90% mortality. The 2014 outbreak infected over 28,000 people, causing 11,325 deaths. Although there is one FDA‐approved vaccine available for limited use, additional vaccines are needed.
Wiggins J, Madapong A, Weaver E.
europepmc +2 more sources
Reston ebolavirus antibodies in bats, the Philippines
Emerging Infectious Diseases, 2011 Filoviruses cause highly lethal hemorrhagic fever in humans and nonhuman primates, except for Reston Ebolavirus (REBOV), which causes severe hemorrhagic fever in macaques (1,2). REBOV epizootics among cynomolgus macaques occurred in 1989, 1990, 1992, and
Fujii, Hikaru +8 more
core +4 more sources
Cell, 2017 Ebola virus disease poses a global health threat. Here, two studies by Wec et al. and Zhao et al. identified vulnerability in an internal fusion loop of an ebolavirus glycoprotein. Monoclonal antibodies elicited from immunization and isolated from a human survivor that recognized epitopes in this area neutralized all five ebolaviruses, guiding the ...
Seiya, Yamayoshi, Yoshihiro, Kawaoka
openaire +2 more sources
PLoS Neglected Tropical Diseases, 2022 Although multiple antigenically distinct ebolavirus species can cause human disease, previous serosurveys focused on only Zaire ebolavirus (EBOV). Thus, the extent of reactivity or exposure to other ebolaviruses, and which sociodemographic factors are ...
Kelly C L Shaffer +18 more
doaj +1 more source
One Health Outlook, 2021 Early detection of Ebola virus spillover into wildlife is crucial for rapid response. We developed and validated a portable, cold-chain independent Ebola virus RT-qPCR assay.
Dania M. Figueroa +14 more
doaj +1 more source
Ebolaviruscomparative genomics [PDF]
FEMS Microbiology Reviews, 2015 (Uploaded by Plazi for the Bat Literature Project) The 2014 Ebola outbreak in West Africa is the largest documented for this virus. To examine the dynamics of this genome, we compare more than 100 currently available ebolavirus genomes to each other and to other viral genomes.
Jun, Se Ran +14 more
openaire +3 more sources
Epidemiology of Ebolaviruses from an Etiological Perspective
Pathogens, 2023 Since the inception of the ebolavirus in 1976, 32 outbreaks have resulted in nearly 15,350 deaths in more than ten countries of the African continent. In the last decade, the largest (2013–2016) and second largest (2018–2020) ebolavirus outbreaks have ...
Sahil Jain +4 more
doaj +1 more source
Ebolavirus and Other Filoviruses [PDF]
, 2007 (Uploaded by Plazi for the Bat Literature Project) Since Ebola fever emerged in Central Africa in 1976, a number of studies have been undertaken to investigate its natural history and to characterize its transmission from a hypothetical reservoir host(s) to humans.
Leroy, E., Gonzalez, J. P., Pourrut, X.
openaire +3 more sources
Ebolavirus: Pseudotypes, Libraries and Standards [PDF]
Future Virology, 2015 Globalization, accompanied by increasing levels of international travel and trade, climate change, altered human behavior and demographics, is leading to the emergence of manifold viral diseases, many of which are highly pathogenic and hence are considered of great public and animal health importance to the global populace [1].
Temperton, Nigel J., Page, Mark
openaire +2 more sources