Results 21 to 30 of about 11,589 (212)

Epidemiology of Ebolaviruses from an Etiological Perspective

Pathogens, 2023
Since the inception of the ebolavirus in 1976, 32 outbreaks have resulted in nearly 15,350 deaths in more than ten countries of the African continent. In the last decade, the largest (2013–2016) and second largest (2018–2020) ebolavirus outbreaks have ...
Sahil Jain, Svetlana Khaiboullina, Ekaterina Martynova, Sergey Morzunov, Manoj Baranwal   +4 more
doaj   +1 more source

Ebolavirus evolution and emergence are associated with land use change. [PDF]

Ecol Monogr
Abstract Anthropogenic land use change facilitates disease emergence by altering the interface between humans and pathogen reservoirs and is hypothesized to drive pathogen evolution. Here, we show a positive association between land use change and the evolution and dispersal of Zaire ebolavirus (EBOV) and Sudan ebolavirus (SUDV).
Lange CE, Barnum TR, McIver DJ, LeBreton M, Karen Saylors, Kumakamba C, Lowes S, Montero E, Cohen RL.   +8 more
europepmc   +2 more sources

Ebola Stigma and Its Impact on Outbreak Control: Lessons From Key Informant Interviews in Central Uganda. [PDF]

Trop Med Int Health
ABSTRACT Objectives The 2022 outbreak of Sudan ebolavirus in central Uganda was the country's largest in two decades. It was accompanied by reports of stigma towards affected individuals, households and communities. The objectives of this study were to (1) describe how Ebola disease stigma emerged and manifested during the 2022 Sudan ebolavirus ...
Paterson A, Kabajaasi O, Adlard F, Dimitrios KH, Cheyne A, Ssewankambo Y, Kaggwa D, Olliaro P, Kenya-Mugisha N, Rojek A.   +9 more
europepmc   +2 more sources

Traits, phylogeny and host cell receptors predict Ebolavirus host status among African mammals.

PLoS Neglected Tropical Diseases, 2022
We explore how animal host traits, phylogenetic identity and cell receptor sequences relate to infection status and mortality from ebolaviruses. We gathered exhaustive databases of mortality from Ebolavirus after exposure and infection status based on ...
Mekala Sundaram, John Paul Schmidt, Barbara A Han, John M Drake, Patrick R Stephens   +4 more
doaj   +1 more source

Tenacious Researchers Identify a Weakness in All Ebolaviruses. [PDF]

, 2018
The Ebolavirus genus has at least five members, four of which are known to cause deadly disease in humans. An ideal therapy or a vaccine would protect against all ebolaviruses, but identifying a common weakness in all of them has remained elusive.
DuBois, Rebecca M
core   +1 more source

VP24-Karyopherin alpha binding affinities differ between Ebolavirus species, nfluencing interferon inhibition and VP24 stability [PDF]

, 2017
Zaire ebolavirus (EBOV), Bundibugyo ebolavirus (BDBV), and Reston ebolavirus (RESTV) belong to the same genus but exhibit different virulence properties.
Alinger, Joshua B, Amarasinghe, Gaya K, Basler, Christopher F, Diederichs, Audrey, Edwards, Megan R, Leung, Daisy W, Schwarz, Toni M   +6 more
core   +2 more sources

Flow cytometry evaluation of the rhesus monkey cellular immunity following the Zaire ebolavirus (Filoviridae; Ebolavirus: Zaire ebolavirus) experimental infection

Problems of Virology, 2021
Introduction. The outbreaks of the Zaire ebolavirus (ZE) disease (ZED) that have arisen in the last decade determine the need to study the infection pathogenesis, the formation of specific immunity forming as well as the development of effective preventive and therapeutic means.
G. V. Borisevich, S. L. Kirillova, I. V. Shatokhina, V. N. Lebedev, N. V. Shagarova, S. I. Syromyatnikova, A. F. Andrus, E. A. Koval’chuk, V. B. Kirillov, M. L. Bespalov, A. A. Petrov, A. V. Koval’chuk, V. B. Pantyukhov, D. A. Kutayev, S. V. Borisevich, S. L. Kuznetsov   +15 more
openaire   +4 more sources

Epitope-based peptide vaccine against Bombali Ebolavirus viral protein 40: An immunoinformatics combined with molecular docking studies

Informatics in Medicine Unlocked, 2021
Bombali Ebolavirus belongs to the RNA group of viruses which causes lethal hemorrhagic fever with a high mortality rate. Despite these facts, yet there is no approved vaccine have been developed for the eradication of Bombali Ebolavirus infections ...
Mujahed I. Mustafa, Shaza W. Shantier, Miyssa I. Abdelmageed, Abdelrafie M. Makhawi   +3 more
doaj   +1 more source

Treatment of Marburg and Ebola hemorrhagic fevers: A strategy for testing new drugs and vaccines under outbreak conditions. [PDF]

, 2008
The filoviruses, Marburg and Ebola, have the dubious distinction of being associated with some of the highest case-fatality rates of any known infectious disease-approaching 90% in many outbreaks.
A.G. Sprecher, Anon., Baize, Basler, Bausch, Bausch, Bausch, Bausch, Bausch, Bausch, Bausch, Bausch, Benjamin Jeffs, Bernard, Borchert, Bosio, Bosio, Boumandouki, Bray, Bray, Bray, Bray, Brummel-Ziedins, Bukreyev, Bwaka, CDC and WHO, Colebunders, Daddario-DiCaprio, Daniel G. Bausch, Dowell, Egbring, Emond, Enterlein, Feldmann, Formenty, Fourrier, Gear, Geisbert, Geisbert, Geisbert, Geisbert, Geisbert, Geisbert, Geisbert, Geisbert, Gibbs, Gupta, Hensley, Hensley, Hensley, Hewlett, Hewlett, Hoenen, Hotchkiss, Huggins, Jahrling, Jahrling, Jahrling, Jeffs, Johnson, Jones, Jones, Khan, Ksiazek, Kudoyarova-Zubavichene, Larkin, Leroy, Leroy, Mahanty, Mahanty, Martin, Martini, Martini, Monath, Mupapa, Mupapa, Nikiforov, Oswald, Parrino, Pattyn, Paul Boumandouki, Peters, Peterson, Peterson, Pourrut, Reid, Rivers, Roberts, Rollin, Sanchez, Schnittler, Schuler, Smith, Spurgers, Stille, Sullivan, Sullivan, Swanepoel, Takada, Todorovitch, Towner, Warfield, Warfield, Warfield, Wilson, Zaki   +105 more
core   +2 more sources

Ebolavirus and Other Filoviruses [PDF]

, 2007
(Uploaded by Plazi for the Bat Literature Project) Since Ebola fever emerged in Central Africa in 1976, a number of studies have been undertaken to investigate its natural history and to characterize its transmission from a hypothetical reservoir host(s) to humans.
Leroy, E., Gonzalez, J. P., Pourrut, X.
openaire   +2 more sources