Exploratory Temporal and Evolutionary Insights into the Filoviridae Family Through Multiprotein Phylogeny [PDF]
MicroorganismsFiloviruses are among the most lethal viral human pathogens known, with significant relevance to public health, yet their evolutionary history remains poorly resolved.
Thiago S. Messias +15 more
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Ebola virus disease: A persistent challenge in global health security [PDF]
Open Veterinary JournalEbola Virus Disease (EVD) is a highly fatal zoonotic disease caused by a negative-stranded RNA virus of the genus Ebolavirus in the family Filoviridae. Since its first discovery in 1976 in Central Africa, the disease has triggered several large outbreaks
Muniroh Muniroh +11 more
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Viral diversity in wild rodents in the regions of Canaã de Carajás and Curionopólis, State of Pará, Brazil [PDF]
Frontiers in MicrobiologyWild rodents serve as crucial reservoirs for zoonotic viruses. Anthropogenic and environmental disruptions, particularly those induced by mining activities, can destabilize rodent populations and facilitate the emergence of viral agents. In the Canaã dos
Adriana Freitas Moraes Monteiro +12 more
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The New Members of Filoviridae Family: Distribution, Natural Reservoirs, Potential Epidemic Danger
Вестник войск РХБ защиты, 2023 The purpose of the work is to analyze the distribution, natural reservoirs and potential epidemic hazard of new members of the Filoviridae family – Bombali viruses (genus Ebolavirus), Lloviu (genus Cuevavirus), Mengla (genus Dianlovirus), Xylang (genus ...
T. E. Sizikova +4 more
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Ebola virus (Filoviridae: Ebolavirus: Zaire ebolavirus): fatal adaptation mutations
Вопросы вирусологии, 2021 Ebola virus disease (EVD) (former Ebola hemorrhagic fever) is one of the most dangerous infectious diseases affecting humans and primates. Since the identification of the first outbreak in 1976, there have been more than 25 outbreaks worldwide, the ...
I. V. Dolzhikova +3 more
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Long-term survival of an urban fruit bat seropositive for Ebola and Lagos bat viruses. [PDF]
PLoS ONE, 2010 Ebolaviruses (EBOV) (family Filoviridae) cause viral hemorrhagic fevers in humans and non-human primates when they spill over from their wildlife reservoir hosts with case fatality rates of up to 90%.
David T S Hayman +7 more
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The role of platelets in the pathogenesis of viral hemorrhagic fevers. [PDF]
PLoS Neglected Tropical Diseases, 2014 Viral hemorrhagic fevers (VHF) are acute zoonotic diseases that, early on, seem to cause platelet destruction or dysfunction. Here we present the four major ways viruses affect platelet development and function and new evidence of molecular factors that ...
Juan C Zapata +2 more
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Viruses, 2018 Angola variant (MARV/Ang) has replaced Mt. Elgon variant Musoke isolate (MARV/MtE-Mus) as the consensus standard variant for Marburg virus research and is regarded as causing a more aggressive phenotype of disease in animal models; however, there is a ...
Paul W. Blair +9 more
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Virus specific antibody - based remedies for the urgent prevention and treatment of Ebola virus disease [PDF]
Терапевтический архив, 2019 The Ebola virus (member of Ebolavirus genus Filoviridae family) is the etiologic agent of extremely hazard human disease with high mortality rates (up to 90%). The most important components of spectrum of therapeutics for special prophylactic and current
T E Sizikova +2 more
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The Glycoproteins of All Filovirus Species Use the Same Host Factors for Entry into Bat and Human Cells but Entry Efficiency Is Species Dependent. [PDF]
PLoS ONE, 2016 Ebola and marburgviruses, members of the family Filoviridae, can cause severe hemorrhagic fever in humans. The ongoing Ebola virus (EBOV) disease epidemic in Western Africa claimed more than 11,300 lives and was associated with secondary cases outside ...
Markus Hoffmann +4 more
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