Exploratory Temporal and Evolutionary Insights into the Filoviridae Family Through Multiprotein Phylogeny [PDF]
MicroorganismsFiloviruses are among the most lethal viral human pathogens known, with significant relevance to public health, yet their evolutionary history remains poorly resolved.
Thiago S. Messias +15 more
doaj +5 more sources
Filoviridae: insights into immune responses to Ebola virus
Exploration of ImmunologyEbola virus (EBOV) is a zoonotic virus comprising of six known different species, designated within the family Filoviridae and genus Ebolavirus. The first recorded outbreak of an EBOV disease (EVD) was in Yambuku, Zaire EBOV (ZEBOV) in 1976, followed by ...
Ingo Fricke +2 more
exaly +4 more sources
Viral diversity in wild rodents in the regions of Canaã de Carajás and Curionopólis, State of Pará, Brazil [PDF]
Frontiers in MicrobiologyWild rodents serve as crucial reservoirs for zoonotic viruses. Anthropogenic and environmental disruptions, particularly those induced by mining activities, can destabilize rodent populations and facilitate the emergence of viral agents. In the Canaã dos
Adriana Freitas Moraes Monteiro +12 more
doaj +2 more sources
Molecular Evolution of Viruses of the Family Filoviridae Based on 97 Whole-Genome Sequences [PDF]
Journal of Virology, 2013 ABSTRACT Viruses in the Ebolavirus and Marburgvirus genera (family Filoviridae ) have been associated with large outbreaks of hemorrhagic fever in human and nonhuman primates.
Pierre Rollin +2 more
exaly +3 more sources
ICTV Virus Taxonomy Profile: <i>Filoviridae</i> 2024. [PDF]
J Gen VirolFiloviridae is a family of negative-sense RNA viruses with genomes of about 13.1–20.9 kb that infect fish, mammals and reptiles. The filovirid genome is a linear, non-segmented RNA with five canonical open reading frames (ORFs) that encode a nucleoprotein (NP), a polymerase cofactor (VP35), a glycoprotein (GP
Biedenkopf N +14 more
europepmc +3 more sources
Global distribution and genetic diversity of orthoebolaviruses: Mapping and evolutionary analysis [PDF]
One HealthOrthoebolavirus genus (Family: Filoviridae) poses an ongoing threat to both human and animal health. To better understand and address this persistent threat, we conducted a comprehensive analysis.
Nuo Cheng +5 more
doaj +2 more sources
The New Members of Filoviridae Family: Distribution, Natural Reservoirs, Potential Epidemic Danger
Вестник войск РХБ защиты, 2023 The purpose of the work is to analyze the distribution, natural reservoirs and potential epidemic hazard of new members of the Filoviridae family – Bombali viruses (genus Ebolavirus), Lloviu (genus Cuevavirus), Mengla (genus Dianlovirus), Xylang (genus ...
T. E. Sizikova +4 more
doaj +1 more source
Ebola virus (Filoviridae: Ebolavirus: Zaire ebolavirus): fatal adaptation mutations
Вопросы вирусологии, 2021 Ebola virus disease (EVD) (former Ebola hemorrhagic fever) is one of the most dangerous infectious diseases affecting humans and primates. Since the identification of the first outbreak in 1976, there have been more than 25 outbreaks worldwide, the ...
I. V. Dolzhikova +3 more
doaj +1 more source
Long-term survival of an urban fruit bat seropositive for Ebola and Lagos bat viruses. [PDF]
PLoS ONE, 2010 Ebolaviruses (EBOV) (family Filoviridae) cause viral hemorrhagic fevers in humans and non-human primates when they spill over from their wildlife reservoir hosts with case fatality rates of up to 90%.
David T S Hayman +7 more
doaj +1 more source
The role of platelets in the pathogenesis of viral hemorrhagic fevers. [PDF]
PLoS Neglected Tropical Diseases, 2014 Viral hemorrhagic fevers (VHF) are acute zoonotic diseases that, early on, seem to cause platelet destruction or dysfunction. Here we present the four major ways viruses affect platelet development and function and new evidence of molecular factors that ...
Juan C Zapata +2 more
doaj +1 more source