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Virus specific antibody - based remedies for the urgent prevention and treatment of Ebola virus disease [PDF]

open access: yesТерапевтический архив, 2019
The Ebola virus (member of Ebolavirus genus Filoviridae family) is the etiologic agent of extremely hazard human disease with high mortality rates (up to 90%). The most important components of spectrum of therapeutics for special prophylactic and current
T E Sizikova   +2 more
doaj   +1 more source

Ebolavirus and Marburgvirus: Insight the Filoviridae family [PDF]

open access: yesMolecular Aspects of Medicine, 2008
Ebolavirus and Marburgvirus (belonging to the Filoviridae family) emerged four decades ago and cause epidemics of haemorrhagic fever with high case-fatality rates. The genome of filoviruses encodes seven proteins. No significant homology is observed between filovirus proteins and any known macromolecule.
Ascenzi P   +7 more
openaire   +7 more sources

The Glycoproteins of All Filovirus Species Use the Same Host Factors for Entry into Bat and Human Cells but Entry Efficiency Is Species Dependent. [PDF]

open access: yesPLoS ONE, 2016
Ebola and marburgviruses, members of the family Filoviridae, can cause severe hemorrhagic fever in humans. The ongoing Ebola virus (EBOV) disease epidemic in Western Africa claimed more than 11,300 lives and was associated with secondary cases outside ...
Markus Hoffmann   +4 more
doaj   +1 more source

The West African ebola virus disease epidemic 2014–2015: A commissioned review

open access: yesNigerian Postgraduate Medical Journal, 2016
The first epidemic of Ebola haemorrhagic disease in West Africa is the largest and longest Ebola epidemic till date, where the outbreak notably involved three countries with distant spread to other countries.
S A Omilabu   +3 more
doaj   +1 more source

ICTV Virus Taxonomy Profile: Filoviridae [PDF]

open access: yesJournal of General Virology, 2019
Members of the family Filoviridae produce variously shaped, often filamentous, enveloped virions containing linear non-segmented, negative-sense RNA genomes of 15–19 kb. Several filoviruses (e.g., Ebola virus) are pathogenic for humans and are highly virulent.
Kuhn, Jens H   +23 more
openaire   +3 more sources

Highly Effective xMAP Multiplex Assay for the Detection and Identification of Hemorrhagic Fever Agents, Including Ebola Virus

open access: yesПроблемы особо опасных инфекций, 2015
Developed has been the oligonucleotide liquid biochip based on xMAP technology, designed for the laboratory detection of particularly dangerous viral pathogens such as Ebola and Marburg filoviruses, and Machupo , Junin, and Lassa arenaviruses.
V. A. Ternovoy   +5 more
doaj   +1 more source

An immunotoxin targeting Ebola virus glycoprotein inhibits Ebola virus production from infected cells.

open access: yesPLoS ONE, 2021
Ebola virus (EBOV), a member of the mononegaviral family Filoviridae, causes severe disease associated with high lethality in humans. Despite enormous progress in development of EBOV medical countermeasures, no anti-EBOV treatment has been approved.
Yingyun Cai   +5 more
doaj   +1 more source

Filoviridae: Insights into Immune Responses to Ebolavirus

open access: yesSSRN Electronic Journal, 2023
Ebola virus is a zoonotic virus comprised of 6 different species designated within the family Filoviridae and genus Ebolavirus. The first recorded outbreak of an Ebola virus (EBOV) was in Yambuku, Zaire (ZEBOV) in 1976, followed by Sudan Ebola virus (SUBOV) later that year. Outbreaks have been increasing throughout the 21st century, and mortality rates
Brent Brown   +4 more
openaire   +2 more sources

Ébola, lo que debemos saber

open access: yesRevista Ciencias Biomédicas, 2020
La entidad conocida como ébola, recibe esa denominación por el nombre del río más cercano al distrito africano, donde se presentaron los primeros casos del brote en la década de los setenta del siglo XX (1).
Comité Editorial
doaj   +1 more source

DYNAMICAL SYSTEM FOR EBOLA OUTBREAK WITHIN QUARANTINE AND VACCINATION TREATMENTS

open access: yesBarekeng, 2023
Ebola Virus Disease (EVD) is an infectious disease with a high mortality rate which is caused by the virus from the family of Filoviridae, genus of Ebolavirus. Therefore, this research works on the developing model of Ebola disease spread with SLSHVEQIHR
Sugian Nurwijaya   +2 more
doaj   +1 more source

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