Global distribution and genetic diversity of orthoebolaviruses: Mapping and evolutionary analysis [PDF]
Orthoebolavirus genus (Family: Filoviridae) poses an ongoing threat to both human and animal health. To better understand and address this persistent threat, we conducted a comprehensive analysis.
Nuo Cheng +5 more
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The New Members of Filoviridae Family: Distribution, Natural Reservoirs, Potential Epidemic Danger
The purpose of the work is to analyze the distribution, natural reservoirs and potential epidemic hazard of new members of the Filoviridae family – Bombali viruses (genus Ebolavirus), Lloviu (genus Cuevavirus), Mengla (genus Dianlovirus), Xylang (genus ...
T. E. Sizikova +4 more
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Ebola virus (Filoviridae: Ebolavirus: Zaire ebolavirus): fatal adaptation mutations
Ebola virus disease (EVD) (former Ebola hemorrhagic fever) is one of the most dangerous infectious diseases affecting humans and primates. Since the identification of the first outbreak in 1976, there have been more than 25 outbreaks worldwide, the ...
I. V. Dolzhikova +3 more
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Long-term survival of an urban fruit bat seropositive for Ebola and Lagos bat viruses. [PDF]
Ebolaviruses (EBOV) (family Filoviridae) cause viral hemorrhagic fevers in humans and non-human primates when they spill over from their wildlife reservoir hosts with case fatality rates of up to 90%.
David T S Hayman +7 more
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The role of platelets in the pathogenesis of viral hemorrhagic fevers. [PDF]
Viral hemorrhagic fevers (VHF) are acute zoonotic diseases that, early on, seem to cause platelet destruction or dysfunction. Here we present the four major ways viruses affect platelet development and function and new evidence of molecular factors that ...
Juan C Zapata +2 more
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Angola variant (MARV/Ang) has replaced Mt. Elgon variant Musoke isolate (MARV/MtE-Mus) as the consensus standard variant for Marburg virus research and is regarded as causing a more aggressive phenotype of disease in animal models; however, there is a ...
Paul W. Blair +9 more
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Viruses of the Filoviridae family
The article considers representatives of the Filoviridae family, some of which are the causative agents of hemorrhagic fever, which is fatal to humans. The current state of development of immunobiological drugs for the treatment and medical prevention of diseases caused by filoviruses has been analyzed.
A. Chernykh, A. Hancharou
openaire +1 more source
Serological Detection of Ebola Virus Exposures in Native Non-human Primates of Southern Nigeria
Ebola viruses (family: Filoviridae) are the cause of Ebola virus disease (EVD), a highly fatal illness characterised by haemorrhagic fever syndrome in both humans and non-human primates (NHPs).
B.N. Ogunro +5 more
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Morphologic Differentiation of Viruses beyond the Family Level
Electron microscopy has been instrumental in the identification of viruses by being able to characterize a virus to the family level. There are a few cases where morphologic or morphogenesis factors can be used to differentiate further, to the genus ...
Cynthia S. Goldsmith
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Approaches to demonstrating the effectiveness of filovirus vaccines: Lessons from Ebola and COVID-19
Zaire ebolavirus (EBOV), Sudan ebolavirus (SUDV) and Marburg virus (MARV), are members of the Filoviridae family that can cause severe disease and death in humans and animals.
Marion F. Gruber +2 more
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