Results 21 to 30 of about 5,335 (167)
PLoS ONE, 2021 Ebola virus (EBOV), a member of the mononegaviral family Filoviridae, causes severe disease associated with high lethality in humans. Despite enormous progress in development of EBOV medical countermeasures, no anti-EBOV treatment has been approved.
Yingyun Cai +5 more
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Small Molecule Inhibition of Mononegavirales RNA Polymerases. [PDF]
J Med VirolABSTRACT The order Mononegavirales includes several non‐segmented negative‐sense RNA viruses that are significant human pathogens, whose transcription and replication depend on multifunctional RNA‐dependent RNA polymerase (L protein). Recent discoveries in cryo‐electron microscopy (cryo‐EM) have elucidated the structures of these polymerases and their ...
Cao CR, Mohammed M, Yang G, Wang D.
europepmc +2 more sources
Revista Ciencias Biomédicas, 2020 La entidad conocida como ébola, recibe esa denominación por el nombre del río más cercano al distrito africano, donde se presentaron los primeros casos del brote en la década de los setenta del siglo XX (1).
Comité Editorial
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Strategic Preparedness of Broad-Spectrum Antivirals for Rapid Response Towards Next Pandemics. [PDF]
Small SciNanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
N SR, Jin GW, Choy JH.
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Development of a Pan-Filoviridae SYBR Green qPCR Assay for Biosurveillance Studies in Bats
Viruses, 2023 Recent studies have indicated that bats are hosts to diverse filoviruses. Currently, no pan-filovirus molecular assays are available that have been evaluated for the detection of all mammalian filoviruses.
Jessica Coertse +5 more
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DYNAMICAL SYSTEM FOR EBOLA OUTBREAK WITHIN QUARANTINE AND VACCINATION TREATMENTS
Barekeng, 2023 Ebola Virus Disease (EVD) is an infectious disease with a high mortality rate which is caused by the virus from the family of Filoviridae, genus of Ebolavirus. Therefore, this research works on the developing model of Ebola disease spread with SLSHVEQIHR
Sugian Nurwijaya +2 more
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Serological Detection of Ebola Virus Exposures in Native Non-human Primates of Southern Nigeria
Journal of Epidemiology and Global Health, 2018 Ebola viruses (family: Filoviridae) are the cause of Ebola virus disease (EVD), a highly fatal illness characterised by haemorrhagic fever syndrome in both humans and non-human primates (NHPs).
B.N. Ogunro +5 more
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NATURAL RESERVOIR OF FILOVIRUSES AND TYPES OF ASSOCIATED EPIDEMIC OUTBREAKS IN AFRICA [PDF]
, 2017 Family Filoviridae includes a set of etiological agents of human hemorrhagic fevers distributed in Africa: Zaire ebolavirus (ZEBOV), Sudan ebolavirus (SUDV), Bundibugyo ebolavirus (BDBV), Taï Forest ebolavirus (TAFV), Marburg marburgvirus (MMARV ...
V. G. Dedkov +6 more
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Approaches to demonstrating the effectiveness of filovirus vaccines: Lessons from Ebola and COVID-19
Frontiers in Immunology, 2023 Zaire ebolavirus (EBOV), Sudan ebolavirus (SUDV) and Marburg virus (MARV), are members of the Filoviridae family that can cause severe disease and death in humans and animals.
Marion F. Gruber +2 more
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Viral fossils in marsupial genomes: secret cellular guardians [PDF]
Microbiology Australia, 2021 Genomic viral integrations, termed endogenous viral elements (EVEs), are fragments of viruses in host chromosomes that provide information about viral evolution and could even help protect the host from infection. In the present study we examined EVEs in
Peter A White +2 more
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