Results 31 to 40 of about 4,558 (162)
Current perspectives on the phylogeny of Filoviridae
Infection, Genetics and Evolution, 2011 (Uploaded by Plazi for the Bat Literature Project) Sporadic fatal outbreaks of disease in humans and non-human primates caused by Ebola or Marburg viruses have driven research into the characterization of these viruses with the hopes of identifying host tropisms and potential reservoirs.
Barrette, Roger W. +3 more
openaire +2 more sources
Viral fossils in marsupial genomes: secret cellular guardians [PDF]
Microbiology Australia, 2021 Genomic viral integrations, termed endogenous viral elements (EVEs), are fragments of viruses in host chromosomes that provide information about viral evolution and could even help protect the host from infection. In the present study we examined EVEs in
Peter A White +2 more
doaj
Approaches to demonstrating the effectiveness of filovirus vaccines: Lessons from Ebola and COVID-19
Frontiers in Immunology, 2023 Zaire ebolavirus (EBOV), Sudan ebolavirus (SUDV) and Marburg virus (MARV), are members of the Filoviridae family that can cause severe disease and death in humans and animals.
Marion F. Gruber +2 more
doaj +1 more source
Marburg Virus Reverse Genetics Systems
Viruses, 2016 The highly pathogenic Marburg virus (MARV) is a member of the Filoviridae family and belongs to the group of nonsegmented negative-strand RNA viruses.
Kristina Maria Schmidt, Elke Mühlberger
doaj +1 more source
An imported case of Bundibugyo virus infection, France, June 2026
EurosurveillanceIn June 2026, an intensive care physician deployed in the Democratic Republic of the Congo and previously vaccinated against Ebola virus developed fatigue, nausea and headaches while returning to France. Bundibugyo virus was identified with RT-PCR.
the Ebola Investigation Team
doaj +1 more source
Cell Reports, 2023 Summary: Ebola virus (EBOV) and Bundibugyo virus (BDBV) belong to the family Filoviridae and cause a severe disease in humans. We previously isolated a large panel of monoclonal antibodies from B cells of human survivors from the 2007 Uganda BDBV ...
Rodrigo I. Santos +8 more
doaj +1 more source
Statins Suppress Ebola Virus Infectivity by Interfering with Glycoprotein Processing
mBio, 2018 Ebola virus (EBOV) infection is a major public health concern due to high fatality rates and limited effective treatments. Statins, widely used cholesterol-lowering drugs, have pleiotropic mechanisms of action and were suggested as potential adjunct ...
Punya Shrivastava-Ranjan +7 more
doaj +1 more source
ProTides for Antiviral Activity Beyond Liver Cells
Chemistry – A European Journal, Volume 32, Issue 21, 1 June 2026.A strategy for obtaining prodrugs of antiviral nucleotides with broad tissue activity is presented that relies on cycloalkyl or cycloalkylalkyl esters, improving uptake and esterase cleavage, and producing nanomolar inhibitors in kidney, colon, and lung cells.
Felix Goebel +5 more
wiley +1 more source
Carbohydrate‐Based Drug Discovery: Synthetic Strategies and Clinical Applications
Israel Journal of Chemistry, Volume 66, Issue 3, May 2026.The picture depicts the molecules discussed in the review. On the left side, the general scaffold of sugars is shown. Next to it are four carbohydrate‐based molecules, including remdesivir, islatravir, empagliflozin, and Globo‐H. Remdesivir and islatravir contain a substituted ribose ring attached to a modified nucleobase.
Stephan Scheeff +2 more
wiley +1 more source
Bombali virus (Filoviridae: Orthoebolavirus: Orthoebolavirus bombaliense)
Вопросы вирусологииIntroduction. Members of genus Orthoebolavirus of family Filoviridae cause severe hemorrhagic fever in humans with high fatality rates (up to 90%). The first outbreaks of disease caused by the members of genus Orthoebolavirus were registered in 1976 in ...
Tatiana E. Sizikova +2 more
doaj +1 more source