Genetics-Based Classification of Filoviruses Calls for Expanded Sampling of Genomic Sequences
Viruses, 2012 We have recently developed a computational approach for hierarchical, genome-based classification of viruses of a family (DEmARC). In DEmARC, virus clusters are delimited objectively by devising a universal family-wide threshold on intra-cluster genetic ...
Chris Lauber +2 more
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The New Members of Filoviridae Family: Distribution, Natural Reservoirs, Potential Epidemic Danger
Вестник войск РХБ защиты, 2023 The purpose of the work is to analyze the distribution, natural reservoirs and potential epidemic hazard of new members of the Filoviridae family – Bombali viruses (genus Ebolavirus), Lloviu (genus Cuevavirus), Mengla (genus Dianlovirus), Xylang (genus ...
T. E. Sizikova +4 more
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Filoviruses: Innate Immunity, Inflammatory Cell Death, and Cytokines
Pathogens, 2022 Filoviruses are a group of single-stranded negative sense RNA viruses. The most well-known filoviruses that affect humans are ebolaviruses and marburgviruses. During infection, they can cause life-threatening symptoms such as inflammation, tissue damage,
Jianlin Lu +2 more
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Serological Evidence of Filovirus Infection in Nonhuman Primates in Zambia
Viruses, 2021 Ebolaviruses and marburgviruses are filoviruses that are known to cause severe hemorrhagic fever in humans and nonhuman primates (NHPs). While some bat species are suspected to be natural reservoirs of these filoviruses, wild NHPs often act as ...
Katendi Changula +9 more
doaj +1 more source
Animal Model Alternatives in Filovirus and Bornavirus Research
Viruses, 2023 The order Mononegavirales contains a variety of highly pathogenic viruses that may infect humans, including the families Filoviridae, Bornaviridae, Paramyxoviridae, and Rhabodoviridae.
Lina Widerspick +3 more
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The Glycoproteins of All Filovirus Species Use the Same Host Factors for Entry into Bat and Human Cells but Entry Efficiency Is Species Dependent. [PDF]
PLoS ONE, 2016 Ebola and marburgviruses, members of the family Filoviridae, can cause severe hemorrhagic fever in humans. The ongoing Ebola virus (EBOV) disease epidemic in Western Africa claimed more than 11,300 lives and was associated with secondary cases outside ...
Markus Hoffmann +4 more
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Development of a Pan-Filoviridae SYBR Green qPCR Assay for Biosurveillance Studies in Bats
Viruses, 2023 Recent studies have indicated that bats are hosts to diverse filoviruses. Currently, no pan-filovirus molecular assays are available that have been evaluated for the detection of all mammalian filoviruses.
Jessica Coertse +5 more
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Genetically Diverse Filoviruses in Rousettus and Eonycteris spp. Bats, China, 2009 and 2015
Emerging Infectious Diseases, 2017 Genetically divergent filoviruses detected in Rousettus and Eonycteris spp. bats in China exhibited 61%–99% nt identity with reported filoviruses, based on partial replicase sequences, and they demonstrated lung tropism.
Xing-Lou Yang +13 more
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Filiviruses of southeast Asia, China and Europe (review)
Журнал инфектологии, 2019 Filoviruses are known as causative agents of severe haemorrhagic fevers with a high mortality rate in humans. Zaire ebolavirus and Marburgvirus, the most known of them, are associated with the occurrence of sporadic cases and outbreaks of hemorrhagic ...
A. M. Porshakov +2 more
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Niemann-Pick C1 Heterogeneity of Bat Cells Controls Filovirus Tropism
Cell Reports, 2020 Summary: Fruit bats are suspected to be natural hosts of filoviruses, including Ebola virus (EBOV) and Marburg virus (MARV). Interestingly, however, previous studies suggest that these viruses have different tropisms depending on the bat species.
Yoshihiro Takadate +15 more
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