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Special Issue “Arenaviruses 2020”
Viruses, 2021 Rodent-borne arenaviruses have been traditionally predominantly associated with certain muroid species from Mastomys/Praomys genera (African arenaviruses) or with species that belong to murid subfamily Cricetidae (New World arenaviruses) [...]
Igor Lukashevich +2 more
exaly +3 more sources
Validation of Inactivation Methods for Arenaviruses
Viruses, 2021 Several of the human-pathogenic arenaviruses cause hemorrhagic fever and have to be handled under biosafety level 4 conditions, including Lassa virus. Rapid and safe inactivation of specimens containing these viruses is fundamental to enable downstream ...
Stephanie Wurr +2 more
exaly +3 more sources
PLoS Pathogens, 2009 The ability of a New World (NW) clade B arenavirus to enter cells using human transferrin receptor 1 (TfR1) strictly correlates with its ability to cause hemorrhagic fever.
Jorge Salazar-Bravo +2 more
exaly +2 more sources
Antibodies to the Glycoprotein GP2 Subunit Cross-React between Old and New World Arenaviruses
MSphere, 2018 Arenaviruses pose a major public health threat and cause numerous infections in humans each year. Although most viruses belonging to this family do not cause disease in humans, some arenaviruses, such as Lassa virus and Machupo virus, are the etiological
Erica Ollmann Saphire +2 more
exaly +3 more sources
Blood, 2013 In this issue of Blood , Loria and colleagues present new aspects on the role of platelets in protecting against both lethal hemorrhagic diathesis and virus replication in viral hemorrhagic fever (VHF), using a murine model of lymphocytic choriomeningitis virus (LMCV) infection.[1][1] The ...
Ricardo Martin Gomez
exaly +4 more sources
Hemorrhagic Fever-Causing Arenaviruses: Lethal Pathogens and Potent Immune Suppressors
Frontiers in Immunology, 2019 Hemorrhagic fevers (HF) resulting from pathogenic arenaviral infections have traditionally been neglected as tropical diseases primarily affecting African and South American regions.
Hinh Ly, Morgan Brisse, Ly Hinh
exaly +3 more sources
Pathogens, 2015 Arenaviruses include multiple human pathogens ranging from the low-risk lymphocytic choriomeningitis virus (LCMV) to highly virulent hemorrhagic fever (HF) causing viruses such as Lassa (LASV), Junin (JUNV), Machupo (MACV), Lujo (LUJV), Sabia (SABV ...
Yuying Liang, Hinh Ly, Liang Yuying
exaly +3 more sources
Cleavage of the Glycoprotein of Arenaviruses
, 2018 The arenaviruses are a large family of emerging negative-stranded RNA viruses that include several severe human pathogens causing hemorrhagic fevers with high mortality. During the arenavirus life cycle, processing of the viral envelope glycoprotein precursor (GPC) by the cellular subtilisin kexin isozyme-1 (SKI-1)/site-1 protease (S1P) is crucial for ...
Stefan Kunz +2 more
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Animal Models of Pathogenic New World Arenaviruses
MicroorganismsSince the emergence of Junín virus in 1953, pathogenic New World arenaviruses have remained a public health concern. These viruses, which also include Machupo virus, Guanarito virus, Sabiá virus, and Chapare virus, cause acute viral hemorrhagic fever and
Thomas Geisbert +2 more
exaly +3 more sources
Activation of the STAT3 Signaling Pathway by the RNA-Dependent RNA Polymerase Protein of Arenavirus
Viruses, 2021 Arenaviruses cause chronic and asymptomatic infections in their natural host, rodents, and several arenaviruses cause severe hemorrhagic fever that has a high mortality in infected humans, seriously threatening public health.
Qingxing Wang +5 more
doaj +1 more source