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Special Issue “Arenaviruses 2020” [PDF]

open access: yesViruses, 2021
Rodent-borne arenaviruses have been traditionally predominantly associated with certain muroid species from Mastomys/Praomys genera (African arenaviruses) or with species that belong to murid subfamily Cricetidae (New World arenaviruses) [...]
Igor S. Lukashevich   +1 more
doaj   +3 more sources

Characterization of non-standard viral genomes during arenavirus infections identifies prominent S RNA intergenic region deletions [PDF]

open access: yesmBio
Arenaviruses, a family of negative-sense RNA viruses spread by rodents, are a leading cause of severe hemorrhagic fever in humans. Due to a paucity of antivirals and vaccines for arenaviruses, there is a need to identify new mechanisms for interfering ...
Matthew Hackbart, Carolina B. López
doaj   +2 more sources

Host-Species Transferrin Receptor 1 Orthologs Are Cellular Receptors for Nonpathogenic New World Clade B Arenaviruses

open access: yesPLoS Pathogens, 2009
The ability of a New World (NW) clade B arenavirus to enter cells using human transferrin receptor 1 (TfR1) strictly correlates with its ability to cause hemorrhagic fever.
Jonathan Abraham   +2 more
exaly   +2 more sources

Validation of Inactivation Methods for Arenaviruses

open access: yesViruses, 2021
Several of the human-pathogenic arenaviruses cause hemorrhagic fever and have to be handled under biosafety level 4 conditions, including Lassa virus. Rapid and safe inactivation of specimens containing these viruses is fundamental to enable downstream ...
Chris Hoffmann   +2 more
exaly   +3 more sources

Development of a new quantitative RT-PCR to detect lymphocytic choriomeningitis virus [PDF]

open access: yesFrontiers in Veterinary Science
Lymphocytic choriomeningitis virus (LCMV) is a neglected rodent-borne virus, with a worldwide distribution. The common mouse Mus musculus acts as reservoir and vector in the biological cycle of the virus.
Laura Herrero   +9 more
doaj   +2 more sources

Antibodies to the Glycoprotein GP2 Subunit Cross-React between Old and New World Arenaviruses

open access: yesMSphere, 2018
Arenaviruses pose a major public health threat and cause numerous infections in humans each year. Although most viruses belonging to this family do not cause disease in humans, some arenaviruses, such as Lassa virus and Machupo virus, are the etiological
Fatima Amanat   +2 more
exaly   +3 more sources

The underlying mechanisms of arenaviral entry through matriglycan [PDF]

open access: yesFrontiers in Molecular Biosciences
Matriglycan, a recently characterized linear polysaccharide, is composed of alternating xylose and glucuronic acid subunits bound to the ubiquitously expressed protein α-dystroglycan (α-DG).
Michael Katz, Ron Diskin
doaj   +2 more sources

Human Hemorrhagic Fever Causing Arenaviruses: Molecular Mechanisms Contributing to Virus Virulence and Disease Pathogenesis

open access: yesPathogens, 2015
Arenaviruses include multiple human pathogens ranging from the low-risk lymphocytic choriomeningitis virus (LCMV) to highly virulent hemorrhagic fever (HF) causing viruses such as Lassa (LASV), Junin (JUNV), Machupo (MACV), Lujo (LUJV), Sabia (SABV ...
Yuying Liang, Hinh Ly
exaly   +3 more sources

La schizophrénie touche aussi les enfants et les adolescents : une des modalités de leur prise en charge est assurée par le CTJA [Centre thérapeutique de jour pour adolescents] [PDF]

open access: yesViruses, 2004
1% des schizophrénies se déclenchent avant l'âge de 10 ans. 20%, une sur cinq, commencent avant l'âge de 18 ans. Et dans 40% des cas de schizophrénie avérée, les premiers signes étaient apparus avant 18 ans.
Dunand, Fabien, Holzer, Laurent
core   +5 more sources

Hemorrhagic Fever-Causing Arenaviruses: Lethal Pathogens and Potent Immune Suppressors

open access: yesFrontiers in Immunology, 2019
Hemorrhagic fevers (HF) resulting from pathogenic arenaviral infections have traditionally been neglected as tropical diseases primarily affecting African and South American regions.
Morgan E Brisse, Hinh Ly
exaly   +3 more sources

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