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Special Issue “Arenaviruses 2020”
Rodent-borne arenaviruses have been traditionally predominantly associated with certain muroid species from Mastomys/Praomys genera (African arenaviruses) or with species that belong to murid subfamily Cricetidae (New World arenaviruses) [...]
Igor S Lukashevich, Juan C de la Torre
exaly +4 more sources
Host-Species Transferrin Receptor 1 Orthologs Are Cellular Receptors for Nonpathogenic New World Clade B Arenaviruses [PDF]
The ability of a New World (NW) clade B arenavirus to enter cells using human transferrin receptor 1 (TfR1) strictly correlates with its ability to cause hemorrhagic fever.
Jorge Salazar-Bravo +2 more
exaly +3 more sources
Validation of Inactivation Methods for Arenaviruses
Several of the human-pathogenic arenaviruses cause hemorrhagic fever and have to be handled under biosafety level 4 conditions, including Lassa virus. Rapid and safe inactivation of specimens containing these viruses is fundamental to enable downstream ...
Stephanie Wurr +2 more
exaly +3 more sources
Lassa and Mopeia viruses produce different RIG-I-activating RNA in the absence of a functional viral exoribonuclease domain [PDF]
All viruses of the genus Mammarenavirus possess an exoribonuclease (ExoN) domain in their nucleoproteins (NP). Through this domain, the NP efficiently prevents the activation of the interferon (IFN) response, presumably by degrading double-stranded RNA ...
Kodie Noy +9 more
doaj +2 more sources
Antibodies to the Glycoprotein GP2 Subunit Cross-React between Old and New World Arenaviruses.
Arenaviruses pose a major public health threat and cause numerous infections in humans each year. Although most viruses belonging to this family do not cause disease in humans, some arenaviruses, such as Lassa virus and Machupo virus, are the etiological
Erica Ollmann Saphire +2 more
exaly +3 more sources
Arenaviruses include multiple human pathogens ranging from the low-risk lymphocytic choriomeningitis virus (LCMV) to highly virulent hemorrhagic fever (HF) causing viruses such as Lassa (LASV), Junin (JUNV), Machupo (MACV), Lujo (LUJV), Sabia (SABV ...
Yuying Liang, Hinh Ly
exaly +3 more sources
Development of a new quantitative RT-PCR to detect lymphocytic choriomeningitis virus [PDF]
Lymphocytic choriomeningitis virus (LCMV) is a neglected rodent-borne virus, with a worldwide distribution. The common mouse Mus musculus acts as reservoir and vector in the biological cycle of the virus.
Laura Herrero +9 more
doaj +2 more sources
Activation of the STAT3 Signaling Pathway by the RNA-Dependent RNA Polymerase Protein of Arenavirus
Arenaviruses cause chronic and asymptomatic infections in their natural host, rodents, and several arenaviruses cause severe hemorrhagic fever that has a high mortality in infected humans, seriously threatening public health.
Qingxing Wang +5 more
doaj +1 more source
The article presents an analysis of studies assessing the effectiveness of new nonspecific medications against hemorrhagic fevers caused by arenaviruses.
Т. Е. Sizikova +2 more
doaj +1 more source
Arenaviruses: Old viruses present new solutions for cancer therapy
Viral-based cancer therapies have tremendous potential, especially in the context of treating poorly infiltrated cold tumors. However, in tumors with intact anti-viral interferon (IFN) pathways, while some oncolytic viruses induce strong innate and ...
Paweł Stachura +5 more
doaj +1 more source

