Results 11 to 20 of about 5,184 (193)

Special Issue “Arenaviruses 2020”

open access: yesViruses, 2021
Rodent-borne arenaviruses have been traditionally predominantly associated with certain muroid species from Mastomys/Praomys genera (African arenaviruses) or with species that belong to murid subfamily Cricetidae (New World arenaviruses) [...]
Igor S Lukashevich   +2 more
exaly   +4 more sources

Host-Species Transferrin Receptor 1 Orthologs Are Cellular Receptors for Nonpathogenic New World Clade B Arenaviruses [PDF]

open access: yesPLoS Pathogens, 2009
The ability of a New World (NW) clade B arenavirus to enter cells using human transferrin receptor 1 (TfR1) strictly correlates with its ability to cause hemorrhagic fever.
Jonathan Abraham   +2 more
exaly   +3 more sources

Validation of Inactivation Methods for Arenaviruses

open access: yesViruses, 2021
Several of the human-pathogenic arenaviruses cause hemorrhagic fever and have to be handled under biosafety level 4 conditions, including Lassa virus. Rapid and safe inactivation of specimens containing these viruses is fundamental to enable downstream ...
Jonas Müller   +2 more
exaly   +4 more sources

Sympatric Occurrence of 3 Arenaviruses, Tanzania

open access: yesEmerging Infectious Diseases, 2010
To determine the specificity of Morogoro virus for its reservoir host, we studied its host range and genetic diversity in Tanzania. We found that 2 rodent species other than Mastomys natalensis mice carry arenaviruses. Analysis of 340 nt of the viral RNA
Joëlle Goüy de Bellocq   +7 more
doaj   +7 more sources

Antibodies to the Glycoprotein GP2 Subunit Cross-React between Old and New World Arenaviruses

open access: yesMSphere, 2018
Arenaviruses pose a major public health threat and cause numerous infections in humans each year. Although most viruses belonging to this family do not cause disease in humans, some arenaviruses, such as Lassa virus and Machupo virus, are the etiological
Fatima Amanat   +2 more
exaly   +4 more sources

Human Hemorrhagic Fever Causing Arenaviruses: Molecular Mechanisms Contributing to Virus Virulence and Disease Pathogenesis

open access: yesPathogens, 2015
Arenaviruses include multiple human pathogens ranging from the low-risk lymphocytic choriomeningitis virus (LCMV) to highly virulent hemorrhagic fever (HF) causing viruses such as Lassa (LASV), Junin (JUNV), Machupo (MACV), Lujo (LUJV), Sabia (SABV ...
Yuying Liang, Hinh Ly, Liang Yuying
exaly   +4 more sources

Hemorrhagic Fever-Causing Arenaviruses: Lethal Pathogens and Potent Immune Suppressors [PDF]

open access: yesFrontiers in Immunology, 2019
Hemorrhagic fevers (HF) resulting from pathogenic arenaviral infections have traditionally been neglected as tropical diseases primarily affecting African and South American regions.
Morgan Brisse, Hinh Ly, Ly Hinh
exaly   +4 more sources

Differential Immune Responses to Hemorrhagic Fever-Causing Arenaviruses

open access: yesVaccines, 2019
The family Arenaviridae contains several pathogens of major clinical importance. The Old World (OW) arenavirus Lassa virus is endemic in West Africa and is estimated to cause up to 300,000 infections each year.
Emily Mantlo   +2 more
doaj   +2 more sources

Envelope Glycoprotein of Arenaviruses [PDF]

open access: yesViruses, 2012
Arenaviruses include lethal human pathogens which pose serious public health threats. So far, no FDA approved vaccines are available against arenavirus infections, and therapeutic options are limited, making the identification of novel drug targets for the development of efficacious therapeutics an urgent need.
Burri, D.J.   +3 more
openaire   +5 more sources

Characterization of non-standard viral genomes during arenavirus infections identifies prominent S RNA intergenic region deletions [PDF]

open access: yesmBio
Arenaviruses, a family of negative-sense RNA viruses spread by rodents, are a leading cause of severe hemorrhagic fever in humans. Due to a paucity of antivirals and vaccines for arenaviruses, there is a need to identify new mechanisms for interfering ...
Matthew Hackbart, Carolina B. López
doaj   +2 more sources

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