Results 31 to 40 of about 6,856 (207)

A Molecular Sensor To Characterize Arenavirus Envelope Glycoprotein Cleavage by Subtilisin Kexin Isozyme 1/Site 1 Protease. [PDF]

, 2016
UNLABELLED: Arenaviruses are emerging viruses including several causative agents of severe hemorrhagic fevers in humans. The advent of next-generation sequencing technology has greatly accelerated the discovery of novel arenavirus species.
Bergeron, E., Burri, D.J., da Palma, J.R., Khatib, A.M., Kunz, S., Oppliger, J., Pasquato, A., Spiropoulou, C.F.   +7 more
core   +1 more source

Differential Immune Responses to Hemorrhagic Fever-Causing Arenaviruses

Vaccines, 2019
The family Arenaviridae contains several pathogens of major clinical importance. The Old World (OW) arenavirus Lassa virus is endemic in West Africa and is estimated to cause up to 300,000 infections each year.
Emily Mantlo, Slobodan Paessler, Cheng Huang   +2 more
doaj   +1 more source

Animal Models of Lassa Fever

Pathogens, 2020
Lassa virus (LASV), the causative agent of Lassa fever, is estimated to be responsible for up to 300,000 new infections and 5000 deaths each year across Western Africa.
Rachel A. Sattler, Slobodan Paessler, Hinh Ly, Cheng Huang   +3 more
doaj   +1 more source

Chapare virus, a newly discovered arenavirus isolated from a fatal hemorrhagic fever case in Bolivia. [PDF]

PLoS Pathogens, 2008
A small focus of hemorrhagic fever (HF) cases occurred near Cochabamba, Bolivia, in December 2003 and January 2004. Specimens were available from only one fatal case, which had a clinical course that included fever, headache, arthralgia, myalgia, and ...
Simon Delgado, Bobbie R Erickson, Roberto Agudo, Patrick J Blair, Efrain Vallejo, César G Albariño, Jorge Vargas, James A Comer, Pierre E Rollin, Thomas G Ksiazek, James G Olson, Stuart T Nichol   +11 more
doaj   +1 more source

Arenavirus Variations Due to Host-Specific Adaptation

Viruses, 2013
Arenavirus particles are enveloped and contain two single-strand RNA genomic segments with ambisense coding. Genetic plasticity of the arenaviruses comes from transcription errors, segment reassortment, and permissive genomic packaging, and results in ...
Juan C. Zapata, Maria S. Salvato
doaj   +1 more source

Molecular characterization of a new highly divergent Mobala related arenavirus isolated from Praomys sp. rodents

Scientific Reports, 2021
Arenaviruses represent a family of viruses that are naturally present in rodents belonging to subfamily Murinae, Neotominae or Sigmodontinae. Except for Lassa virus, little information is available on other Old-World arenaviruses.
Huguette Simo Tchetgna, Stephane Descorps-Declère, Benjamin Selekon, Aurelia Kwasiborski, Mathias Vandenbogaert, Jean-Claude Manuguerra, Antoine Gessain, Valérie Caro, Emmanuel Nakouné, Nicolas Berthet   +9 more
doaj   +1 more source

Co-infecting Reptarenaviruses Can Be Vertically Transmitted in Boa Constrictor [PDF]

, 2017
Boid inclusion body disease (BIBD) is an often fatal disease affecting mainly constrictor snakes. BIBD has been associated with infection, and more recently with coinfection, by various reptarenavirus species (family Arenaviridae). Thus far BIBD has only
Hepojoki, Jussi, Hetzel, Udo, Keller, Saskia, Kipar, Anja, Korzyukov, Yegor, Sironen, Tarja, Vapalahti, Olli   +6 more
core   +2 more sources

Novel Arenavirus, Zambia

Emerging Infectious Diseases, 2011
To investigate arenavirus in Zambia, we characterized virus from the kidneys of 5 arenavirus RNA–positive rodents (Mastomys natalensis) among 263 captured.
Akihiro Ishii, Yuka Thomas, Ladslav Moonga, Ichiro Nakamura, Aiko Ohnuma, Bernard M. Hang’ombe, Ayato Takada, Aaron S. Mweene, Hirofumi Sawa   +8 more
doaj   +1 more source

Validation of Сhoice of Laboratory Model for Preclinical Estimation of Medical Protectors Against Bolivian Hemorrhagic Fever

Вестник войск РХБ защиты, 2023
This review is dedicated to the peculiarities of pathogenesis of the experimental Bolivian hemorrhagic fever (BHF) - the disease, caused by Machupo virus (Arenaviridae family).
T. E. Sizikova, V. N. Lebedev, V. B. Pantukhov, E. Y. Vakhnov, S. V. Borisevich   +4 more
doaj   +1 more source

Topoisomerase II as a Novel Antiviral Target against Panarenaviral Diseases

Viruses, 2022
Although many arenaviruses cause severe diseases with high fatality rates each year, treatment options are limited to off-label use of ribavirin, and a Food and Drug Administration (FDA)-approved vaccine is not available.
Tosin Oladipo Afowowe, Yasuteru Sakurai, Shuzo Urata, Vahid Rajabali Zadeh, Jiro Yasuda   +4 more
doaj   +1 more source