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The Current State of Vaccine Development for Specific Prophylactics of Arenaviral Hemorrhagic Fevers
Проблемы особо опасных инфекций, 2018 Presently, the Arenavirus genus (Arenaviridae family) includes 26 individual species of viruses. It is divided into two main groups – Old World arenaviruses and New World arenaviruses.
T. E. Sizikova +3 more
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MOLECULAR-BIOLOGICAL PECULIARITIES OF ARENAVIRUS REPRODUCTION IN SENSITIVE CELLS
Проблемы особо опасных инфекций, 2017 The Arenaviridae family consists of a large group of single strand ambisense RNA viruses that are separated phylogenetically, serologically and geographically into Old World and New World viruses.
T. E. Sizikova +4 more
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Differential Immune Responses to Hemorrhagic Fever-Causing Arenaviruses
Vaccines, 2019 The family Arenaviridae contains several pathogens of major clinical importance. The Old World (OW) arenavirus Lassa virus is endemic in West Africa and is estimated to cause up to 300,000 infections each year.
Emily Mantlo +2 more
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Arenavirus Variations Due to Host-Specific Adaptation
Viruses, 2013 Arenavirus particles are enveloped and contain two single-strand RNA genomic segments with ambisense coding. Genetic plasticity of the arenaviruses comes from transcription errors, segment reassortment, and permissive genomic packaging, and results in ...
Juan C. Zapata, Maria S. Salvato
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Chapare virus, a newly discovered arenavirus isolated from a fatal hemorrhagic fever case in Bolivia. [PDF]
PLoS Pathogens, 2008 A small focus of hemorrhagic fever (HF) cases occurred near Cochabamba, Bolivia, in December 2003 and January 2004. Specimens were available from only one fatal case, which had a clinical course that included fever, headache, arthralgia, myalgia, and ...
Simon Delgado +11 more
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Emerging Infectious Diseases, 2011 To investigate arenavirus in Zambia, we characterized virus from the kidneys of 5 arenavirus RNA–positive rodents (Mastomys natalensis) among 263 captured.
Akihiro Ishii +8 more
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Scientific Reports, 2021 Arenaviruses represent a family of viruses that are naturally present in rodents belonging to subfamily Murinae, Neotominae or Sigmodontinae. Except for Lassa virus, little information is available on other Old-World arenaviruses.
Huguette Simo Tchetgna +9 more
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Pathogens, 2020 Lassa virus (LASV), the causative agent of Lassa fever, is estimated to be responsible for up to 300,000 new infections and 5000 deaths each year across Western Africa.
Rachel A. Sattler +3 more
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Вестник войск РХБ защиты, 2023 This review is dedicated to the peculiarities of pathogenesis of the experimental Bolivian hemorrhagic fever (BHF) - the disease, caused by Machupo virus (Arenaviridae family).
T. E. Sizikova +4 more
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Topoisomerase II as a Novel Antiviral Target against Panarenaviral Diseases
Viruses, 2022 Although many arenaviruses cause severe diseases with high fatality rates each year, treatment options are limited to off-label use of ribavirin, and a Food and Drug Administration (FDA)-approved vaccine is not available.
Tosin Oladipo Afowowe +4 more
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