Results 41 to 50 of about 5,397 (165)
Repurposed Medicines for Viruses With Epidemic or Pandemic Potential: A Horizon Scan
Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.ABSTRACT Viruses such as Ebola, Marburg, influenza, mpox, MERS‐CoV, SARS‐CoV, and SARS‐CoV‐2 may be considered pathogens of epidemic or pandemic concern. Developing novel antiviral medicines can be time‐consuming and resource intensive. Repurposing existing medicines with known or potential antiviral activity offers a faster, cost‐effective strategy to
Sola Akinbolade +5 more
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The Mengla virus (Filoviridae: Dianlovirus)
Вопросы вирусологииIntroduction. Filoviruses associated with various species of pteropodid bats (Chiroptera: Pteropodidae) are traditionally regarded as potential causative agents of hemorrhagic fevers with epidemic potential.
Tatyana E. Sizikova +2 more
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Проблемы особо опасных инфекций, 2018 Among the viruses transmitted by Chiroptera, filoviruses, lissaviruses, henipaviruses, and coronaviruses pose the major threat to humans. The featured review is devoted to the analysis of the results of studies on the role of African Chiropterans in the ...
A. M. Porshakov +3 more
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Carbohydrate‐Based Drug Discovery: Synthetic Strategies and Clinical Applications
Israel Journal of Chemistry, Volume 66, Issue 3, May 2026.The picture depicts the molecules discussed in the review. On the left side, the general scaffold of sugars is shown. Next to it are four carbohydrate‐based molecules, including remdesivir, islatravir, empagliflozin, and Globo‐H. Remdesivir and islatravir contain a substituted ribose ring attached to a modified nucleobase.
Stephan Scheeff +2 more
wiley +1 more source
Filoviruses in Bats: Current Knowledge and Future Directions
Viruses, 2014 Filoviruses, including Ebolavirus and Marburgvirus, pose significant threats to public health and species conservation by causing hemorrhagic fever outbreaks with high mortality rates. Since the first outbreak in 1967, their origins, natural history, and
Kevin J. Olival, David T. S. Hayman
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γδ T Cells in Emerging Viral Infection: An Overview
Viruses, 2022 New emerging viruses belonging to the Coronaviridae, Flaviviridae, and Filoviridae families are serious threats to public health and represent a global concern.
Eleonora Cimini, Chiara Agrati
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Microbial Biotechnology, Volume 19, Issue 5, May 2026.Chemical structure of RIBOTAC inhibitor with metabolic handle binding as nucleotide analogue to SARS‐CoV‐2 RNA dependent RNA polymerase, its linker and the RNase L recruiter which binds RNase L monomers and mediates their dimerization that actives nuclease activity degrading the viral RNA.
Harald Brüssow
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Filovirus Neutralising Antibodies: Mechanisms of Action and Therapeutic Application
Pathogens, 2021 Filoviruses, especially Ebola virus, cause sporadic outbreaks of viral haemorrhagic fever with very high case fatality rates in Africa. The 2013–2016 Ebola epidemic in West Africa provided large survivor cohorts spurring a large number of human studies ...
Alexander Hargreaves +5 more
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Inhibition of Ebola Virus by Anti-Ebola miRNAs in silico
Journal of Infection in Developing Countries, 2016 Introduction: MicroRNAs (miRNAs) are small, noncoding RNA molecules that regulate transcriptional and posttranscriptional gene regulation of the organisms. miRNA provides immune defense when the body is faced with challenges intracellular agents.
Zhabiz Golkar +3 more
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Vaccines, 2022 Vaccines are needed to disrupt or prevent continued outbreaks of filoviruses in humans across Western and Central Africa, including outbreaks of Marburg virus (MARV). As part of a filovirus vaccine product development plan, it is important to investigate
Christopher L. Cooper +21 more
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