Results 61 to 70 of about 8,507 (211)

Endocytic Pathways Involved in Filovirus Entry: Advances, Implications and Future Directions

open access: yesViruses, 2012
Detailed knowledge of the host-virus interactions that accompany filovirus entry into cells is expected to identify determinants of viral virulence and host range, and to yield targets for the development of antiviral therapeutics.
Suchita Bhattacharyya   +2 more
doaj   +1 more source

Introducing EbolaCheck: potential for point-of-need infectious disease diagnosis [PDF]

open access: yes, 2015
The 2013–2015 Ebolavirus disease humanitarian crisis has spurred the development of laboratory-free, point-of-care nucleic acid testing solutions.
Christie A   +6 more
core   +1 more source

Vaccination and transfusion safety at the time of expanding use of live attenuated vaccines

open access: yes
Vox Sanguinis, EarlyView.
Pierre Tiberghien   +4 more
wiley   +1 more source

Production of human cathepsins using Expi293™ mammalian cell expression system for off‐target activity of cysteine protease inhibitor screening

open access: yesProtein Science, Volume 34, Issue 11, November 2025.
Abstract Following the SARS‐CoV‐2 pandemic, many direct‐acting antivirals targeting viral cysteine protease were developed. SARS‐CoV‐2, as well as other viruses, rely on cysteine proteases for their replication, suggesting future generations of antivirals targeting cysteine proteases will emerge.
Zoe Turner   +9 more
wiley   +1 more source

Organoid Models to Study Human Infectious Diseases

open access: yesCell Proliferation, Volume 58, Issue 11, November 2025.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu   +4 more
wiley   +1 more source

Increasing Occurrence of Marburg Virus Outbreaks in Africa: Risk Assessment for Public Health

open access: yesMicrobial Biotechnology, Volume 18, Issue 9, September 2025.
Bat and Marburg virus (Filovirus). Left: A Rousettus aegyptiacus bat; Center: a distribution map of R. aegyptiacus; Right: EM of Marburg virus. (figure credits: Left Wikipedia Nilflughund Lithuanian Zoological Gardens, Center; Center: Wikipedia Nilflughund IUCN Red List of Threatened Species, right Wikipedia Marburg virus CDC Fred Murphy; J.
Harald Brüssow
wiley   +1 more source

The vaccines based on the replicon of the venezuelan equine encephalomyelitis virus against viral hemorrhagic fevers

open access: yesВопросы вирусологии, 2015
The status of the various recombinant DNA and RNA-derived candidate vaccines, as well as the Venezuelan equine encephalomyelitis virus (VEEV) replicon vaccine system against extremely hazardous viral hemorrhagic fevers, were reviewed.
A. A. Petrov   +4 more
doaj  

Implication of a retrovirus-like glycoprotein peptide in the immunopathogenesis of Ebola and Marburg viruses [PDF]

open access: yes, 2006
Ebola and Marburg viruses can cause hemorrhagic fever (HF) outbreaks with high mortality in primates. Whereas Marburg (MARV), Ebola Zaire (ZEBOV), and Ebola Sudan (SEBOV) viruses are pathogenic in humans, apes, and monkeys, Ebola Reston (REBOV) is ...
Chen, Ivy   +6 more
core   +3 more sources

The Antiviral Activity of Polyphenols

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 15, August 2025.
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard   +5 more
wiley   +1 more source

Diverse hosts, diverse immune systems: Evolutionary variation in bat immunology

open access: yesAnnals of the New York Academy of Sciences, Volume 1550, Issue 1, Page 151-172, August 2025.
Bats are recognized to have distinct immune systems from other vertebrates that may allow them to host virulent pathogens without showing disease. However, these flying mammals are also incredibly diverse, such that bats should not be expected to be immunologically homogenous.
Daniel J. Becker   +11 more
wiley   +1 more source

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