Results 71 to 80 of about 5,423 (165)

Treatment of Ebola Virus Disease: From Serotherapy to the Use of Monoclonal Antibodies

Antibodies
Ebola virus disease (EVD) is an acute illness with a high-case fatality rate (CFR) caused by an RNA virus belonging to the Filoviridae family. Over the past 50 years, regular EVD outbreaks have been reported.
Dmitriy N. Shcherbakov, Anastasiya A. Isaeva, Egor A. Mustaev   +2 more
doaj   +1 more source

Filovirus infections: science and innovation

Сибирский научный медицинский журнал
Epidemics of Filovirus Hemorrhagic Fevers demonstrate an increase in incidence, a reduction in the intervals between outbreaks, the emergence of a risk of infection spreading to non-endemic regions in recent years.
L. N. Aftaeva, V. L. Melnikov, A. V. Arekhina   +2 more
doaj   +1 more source

Emerging virus diseases: can we ever expect the unexpected?

Emerging Microbes and Infections, 2012
Emerging virus diseases are a major threat to human and veterinary public health. With new examples occurring approximately one each year, the majority are viruses originating from an animal host.
Colin R Howard, Nicola F Fletcher
doaj   +1 more source

Endocytic Pathways Involved in Filovirus Entry: Advances, Implications and Future Directions

Viruses, 2012
Detailed knowledge of the host-virus interactions that accompany filovirus entry into cells is expected to identify determinants of viral virulence and host range, and to yield targets for the development of antiviral therapeutics.
Suchita Bhattacharyya, Kartik Chandran, Nirupama Mulherkar   +2 more
doaj   +1 more source

Strategic and Technical Considerations in Manufacturing Viral Vector Vaccines for the Biomedical Advanced Research and Development Authority Threats

Vaccines
Over the past few decades, the world has seen a considerable uptick in the number of new and emerging infectious disease outbreaks. The development of new vaccines, vaccine technologies, and platforms are critical to enhance our preparedness for ...
Lindsay A. Parish, Shyam Rele, Kimberly A. Hofmeyer, Brooke B. Luck, Daniel N. Wolfe   +4 more
doaj   +1 more source

Comparative analysis of the taxonomic classification criteria for a number of groups of pathogenic DNA and RNA viruses based on genomic data

Вопросы вирусологии
The basis for criteria of the taxonomic classification of DNA and RNA viruses based on data of the genomic sequencing are viewed in this review. The genomic sequences of viruses, which have genome represented by double-stranded DNA (orthopoxviruses as ...
Tatiana E. Sizikova, Vitaliy N. Lebedev, Sergey V. Borisevich   +2 more
doaj   +1 more source

Innate immune evasion by filoviruses

Virology, 2015
Ebola viruses and Marburg viruses, members of the filovirus family, cause severe hemorrhagic fever. The ability of these viruses to potently counteract host innate immune responses is thought to be an important component of viral pathogenesis. Several mechanisms of filoviral innate immune evasion have been defined and are reviewed here.
openaire   +2 more sources

Filoviruses [PDF]

The Journal of Infectious Diseases, 2011
openaire   +1 more source

Bundibugyo virus-perspectives for the current outbreak. [PDF]

Npj Viruses
Hoenen T.
europepmc   +1 more source

Why is there still no licensed vaccine for Bundibugyo ebolavirus? Lessons from the 2026 outbreaks in Uganda and the Democratic Republic of Congo. [PDF]

New Microbes New Infect
Abdi AM, Omar AM, Khalif IA, Adan AM, Bashir SG.   +4 more
europepmc   +1 more source