Results 91 to 100 of about 8,507 (211)

Shedding Light on Filovirus Infection with High-Content Imaging

open access: yesViruses, 2012
Microscopy has been instrumental in the discovery and characterization of microorganisms. Major advances in high-throughput fluorescence microscopy and automated, high-content image analysis tools are paving the way to the systematic and quantitative ...
Rekha G. Panchal   +2 more
doaj   +1 more source

Global trends in infectious diseases at the wildlife–livestock interface [PDF]

open access: yes, 2015
The role and significance of wildlife–livestock interfaces in disease ecology has largely been neglected, despite recent interest in animals as origins of emerging diseases in humans. Scoping review methods were applied to objectively assess the relative
Anke K. Wiethoelter   +11 more
core   +2 more sources

Laboratory detection and diagnosis of filoviruses

open access: yesVirologica Sinica, 2011
Ebola virus (EBOV) and Marburg virus (MARV), belonging to the Filoviridae family, emerged four decades ago and caused severe viral hemorrhagic fever in human and other primates. As high as 50-90% mortality, filoviruses can cause significant threats to public health.
Yun-peng, Wang   +2 more
openaire   +3 more sources

Seroprevalence of Antibodies to Filoviruses with Outbreak Potential in Sub-Saharan Africa: A Systematic Review to Inform Vaccine Development and Deployment

open access: yesVaccines
Background/Objectives: Orthoebolaviruses and orthomarburgviruses are filoviruses that can cause viral hemorrhagic fever and significant morbidity and mortality in humans.
Christopher S. Semancik   +12 more
doaj   +1 more source

A Diacylglycerol Kinase Inhibitor, R-59-022, Blocks Filovirus Internalization in Host Cells

open access: yesViruses, 2019
Filoviruses, such as Ebola virus (EBOV) and Marburg virus, are causative agents of unpredictable outbreaks of severe hemorrhagic fevers in humans and non-human primates.
Corina M. Stewart   +8 more
doaj   +1 more source

Diabetes as a tracer condition in international benchmarking of health systems.

open access: yes, 2006
OBJECTIVE: To assess the performance of health systems using diabetes as a tracer condition. RESEARCH DESIGN AND METHODS: We generated a measure of "case-fatality" among young people with diabetes using the mortality-to-incidence ratio (M/I ratio) for 29
Bain, Chris, McKee, Martin, Nolte, Ellen
core   +1 more source

Filovirus Research: The Need for an Integrated Approach in Time and Space [PDF]

open access: yes
The episodic appearance of Ebola virus (EBOV) and Marburg virus (MARV) across central Africa over the last 15 years not only underscores the importance of filoviruses as uniquely virulent agents to both human and wildlife communities but also implies a ...
Pinzon, Jorge E.
core   +1 more source

Innate immune evasion by filoviruses

open access: yesVirology, 2015
Ebola viruses and Marburg viruses, members of the filovirus family, cause severe hemorrhagic fever. The ability of these viruses to potently counteract host innate immune responses is thought to be an important component of viral pathogenesis. Several mechanisms of filoviral innate immune evasion have been defined and are reviewed here.
openaire   +2 more sources

Strategic and Technical Considerations in Manufacturing Viral Vector Vaccines for the Biomedical Advanced Research and Development Authority Threats

open access: yesVaccines
Over the past few decades, the world has seen a considerable uptick in the number of new and emerging infectious disease outbreaks. The development of new vaccines, vaccine technologies, and platforms are critical to enhance our preparedness for ...
Lindsay A. Parish   +4 more
doaj   +1 more source

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