Treatment of Ebola Virus Disease: From Serotherapy to the Use of Monoclonal Antibodies
AntibodiesEbola virus disease (EVD) is an acute illness with a high-case fatality rate (CFR) caused by an RNA virus belonging to the Filoviridae family. Over the past 50 years, regular EVD outbreaks have been reported.
Dmitriy N. Shcherbakov +2 more
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Filovirus infections: science and innovation
Сибирский научный медицинский журналEpidemics of Filovirus Hemorrhagic Fevers demonstrate an increase in incidence, a reduction in the intervals between outbreaks, the emergence of a risk of infection spreading to non-endemic regions in recent years.
L. N. Aftaeva +2 more
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Viewpoint: filovirus haemorrhagic fever outbreaks: much ado about nothing? [PDF]
, 2000 The recent outbreak of Marburg haemorrhagic fever in the Democratic Republic of Congo has put the filovirus threat back on the international health agenda.
Boelaert, M +7 more
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Inhibition of Ebola Virus by Anti-Ebola miRNAs in silico
Journal of Infection in Developing Countries, 2016 Introduction: MicroRNAs (miRNAs) are small, noncoding RNA molecules that regulate transcriptional and posttranscriptional gene regulation of the organisms. miRNA provides immune defense when the body is faced with challenges intracellular agents.
Zhabiz Golkar +3 more
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An upstream open reading frame modulates ebola virus polymerase translation and virus replication [PDF]
, 2013 Ebolaviruses, highly lethal zoonotic pathogens, possess longer genomes than most other non-segmented negative-strand RNA viruses due in part to long 5' and 3' untranslated regions (UTRs) present in the seven viral transcriptional units. To date, specific
Amarasinghe, Gaya K +7 more
core +4 more sources
The Molecular Genetic Peculiarities of Genomic Structure of Members of the Ebolavirus Genus
Проблемы особо опасных инфекций, 2015 The molecular genetic peculiarities of genomic structure of the Ebolavirus genus members are viewed in the review. The Ebola virus disease outbreaks in West African countries constitute a threat not only for Africa, but for the whole world in view of ...
A. A. Petrov +8 more
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Проблемы особо опасных инфекций, 2014 The members of the Filoviridae (Marburg and Ebola viruses) and Arenaviridae (Lassa, Lujo, Machupo, Junin, Guanarito, Sabia viruses) families are the etiological agents of particularly dangerous viral hemorrhagic fevers.
A. A. Petrov +6 more
doaj +1 more source
Marburg Virus Reverse Genetics Systems
Viruses, 2016 The highly pathogenic Marburg virus (MARV) is a member of the Filoviridae family and belongs to the group of nonsegmented negative-strand RNA viruses.
Kristina Maria Schmidt, Elke Mühlberger
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Mission to Indonesia to participate to the 1st Indonesia- France Seminar in Medicine & Public Health and investigate potential collaborations on animal health : 2nd - 9th of November 2012 [PDF]
, 2012 Emerging and zoonotic infectious diseases are a major issue in Indonesia. The objective of this mission, funded by the Institut Français d'Indonésie (IFI), was to identify potential subjects of collaboration between CIRAD, Pasteur Institute, and ...
Bourhy, Hervé +2 more
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A systematic review and meta-analysis of seroprevalence surveys of ebolavirus infection. [PDF]
, 2017 Asymptomatic ebolavirus infection could greatly influence transmission dynamics, but there is little consensus on how frequently it occurs or even if it exists. This paper summarises the available evidence on seroprevalence of Ebola, Sudan and Bundibugyo
Bower, Hilary, Glynn, Judith R
core +2 more sources