Treatment of Marburg and Ebola hemorrhagic fevers: A strategy for testing new drugs and vaccines under outbreak conditions. [PDF]
The filoviruses, Marburg and Ebola, have the dubious distinction of being associated with some of the highest case-fatality rates of any known infectious disease-approaching 90% in many outbreaks.
A.G. Sprecher +105 more
core +2 more sources
Filiviruses of southeast Asia, China and Europe (review)
Filoviruses are known as causative agents of severe haemorrhagic fevers with a high mortality rate in humans. Zaire ebolavirus and Marburgvirus, the most known of them, are associated with the occurrence of sporadic cases and outbreaks of hemorrhagic ...
A. M. Porshakov +2 more
doaj +1 more source
Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats [PDF]
Biological factors that influence the host range and spillover of Ebola virus (EBOV) and other filoviruses remain enigmatic. While filoviruses infect diverse mammalian cell lines, we report that cells from African straw-colored fruit bats (Eidolon helvum)
Agnarsson +78 more
core +2 more sources
LLOVIU VIRUS - A NOVEL FILOVIRUS, ENDEMIC IN EUROPE
The data on a recently revealed novel filovirus (Lloviu virus, family Filoviridae, genera Cuevavirus) in Europe are viewed in this issue. The molecular-biological properties of genome fragments of Lloviu virus were isolated from perished bats ...
T. E. Sizikova +3 more
doaj +1 more source
Intracellular Events and Cell Fate in Filovirus Infection
Marburg and Ebola viruses cause a severe hemorrhagic disease in humans with high fatality rates. Early target cells of filoviruses are monocytes, macrophages, and dendritic cells. The infection spreads to the liver, spleen and later other organs by blood
Elena Ryabchikova +3 more
doaj +1 more source
AAV Vectored Immunoprophylaxis for Filovirus Infections
Filoviruses are among the deadliest infectious agents known to man, causing severe hemorrhagic fever, with up to 90% fatality rates. The 2014 Ebola outbreak in West Africa resulted in over 28,000 infections, demonstrating the large-scale human health and
Amira D. Rghei +8 more
doaj +1 more source
Virus taxonomy: the database of the International Committee on Taxonomy of Viruses (ICTV) [PDF]
The International Committee on Taxonomy of Viruses (ICTV) is charged with the task of developing, refining, and maintaining a universal virus taxonomy.
Dempsey, Donald M. +5 more
core +3 more sources
Recommendations for dealing with waste contaminated with Ebola virus: a Hazard Analysis of Critical Control Points approach [PDF]
Objective To assess, within communities experiencing Ebola virus outbreaks, the risks associated with the disposal of human waste and to generate recommendations for mitigating such risks.
Ahmed A Mohamedani +25 more
core +2 more sources
Marburg virus survivor immune responses are Th1 skewed with limited neutralizing antibody responses. [PDF]
Until recently, immune responses in filovirus survivors remained poorly understood. Early studies revealed IgM and IgG responses to infection with various filoviruses, but recent outbreaks have greatly expanded our understanding of filovirus immune ...
Agrati +54 more
core +4 more sources
γδ T Cells in Emerging Viral Infection: An Overview
New emerging viruses belonging to the Coronaviridae, Flaviviridae, and Filoviridae families are serious threats to public health and represent a global concern.
Eleonora Cimini, Chiara Agrati
doaj +1 more source

