Results 21 to 30 of about 5,397 (165)

Filiviruses of southeast Asia, China and Europe (review)

Журнал инфектологии, 2019
Filoviruses are known as causative agents of severe haemorrhagic fevers with a high mortality rate in humans. Zaire ebolavirus and Marburgvirus, the most known of them, are associated with the occurrence of sporadic cases and outbreaks of hemorrhagic ...
A. M. Porshakov, Yu. V. Kononova, T. M. Luong   +2 more
doaj   +1 more source

Niemann-Pick C1 Heterogeneity of Bat Cells Controls Filovirus Tropism

Cell Reports, 2020
Summary: Fruit bats are suspected to be natural hosts of filoviruses, including Ebola virus (EBOV) and Marburg virus (MARV). Interestingly, however, previous studies suggest that these viruses have different tropisms depending on the bat species.
Yoshihiro Takadate, Tatsunari Kondoh, Manabu Igarashi, Junki Maruyama, Rashid Manzoor, Hirohito Ogawa, Masahiro Kajihara, Wakako Furuyama, Masahiro Sato, Hiroko Miyamoto, Reiko Yoshida, Terence E. Hill, Alexander N. Freiberg, Heinz Feldmann, Andrea Marzi, Ayato Takada   +15 more
doaj   +1 more source

LLOVIU VIRUS - A NOVEL FILOVIRUS, ENDEMIC IN EUROPE

Вопросы вирусологии, 2018
The data on a recently revealed novel filovirus (Lloviu virus, family Filoviridae, genera Cuevavirus) in Europe are viewed in this issue. The molecular-biological properties of genome fragments of Lloviu virus were isolated from perished bats ...
T. E. Sizikova, V. N. Lebedev, N. V. Karulina, S. V. Borisevich   +3 more
doaj   +1 more source

Genomic transfers help to decipher the ancient evolution of filoviruses and interactions with vertebrate hosts [PDF]

PLoS Pathogens
Derek Taylor
exaly   +2 more sources

AAV Vectored Immunoprophylaxis for Filovirus Infections

Tropical Medicine and Infectious Disease, 2020
Filoviruses are among the deadliest infectious agents known to man, causing severe hemorrhagic fever, with up to 90% fatality rates. The 2014 Ebola outbreak in West Africa resulted in over 28,000 infections, demonstrating the large-scale human health and
Amira D. Rghei, Laura P. van Lieshout, Lisa A. Santry, Matthew M. Guilleman, Sylvia P. Thomas, Leonardo Susta, Khalil Karimi, Byram W. Bridle, Sarah K. Wootton   +8 more
doaj   +1 more source

Intracellular Events and Cell Fate in Filovirus Infection

Viruses, 2011
Marburg and Ebola viruses cause a severe hemorrhagic disease in humans with high fatality rates. Early target cells of filoviruses are monocytes, macrophages, and dendritic cells. The infection spreads to the liver, spleen and later other organs by blood
Elena Ryabchikova, Ronald B. Corley, Elke Mühlberger, Judith Olejnik   +3 more
doaj   +1 more source

Serologic Evidence of Fruit Bat Exposure to Filoviruses, Singapore, 2011–2016

Emerging Infectious Diseases, 2018
To determine whether fruit bats in Singapore have been exposed to filoviruses, we screened 409 serum samples from bats of 3 species by using a multiplex assay that detects antibodies against filoviruses.
Eric D. Laing, Ian H. Mendenhall, Martin Linster, Dolyce H. W. Low, Yihui Chen, Lianying Yan, Spencer L. Sterling, Sophie Borthwick, Erica Sena Neves, Julia S. L. Lim, Maggie Skiles, Benjamin P. Y.-H. Lee, Lin-Fa Wang, Christopher C. Broder, Gavin J. D. Smith   +14 more
doaj   +1 more source

Detection of Filoviruses in Bats in Vietnam

Viruses, 2023
A new filovirus named Měnglà virus was found in bats in southern China in 2015. This species has been assigned to the new genus Dianlovirus and has only been detected in China. In this article, we report the detection of filoviruses in bats captured in Vietnam. We studied 248 bats of 15 species caught in the provinces of Lai Chau and Son La in northern
Marat T. Makenov, Lan Anh T. Le, Olga A. Stukolova, Ekaterina V. Radyuk, Evgeny S. Morozkin, Nga T. T. Bui, Olga B. Zhurenkova, Manh N. Dao, Chau V. Nguyen, Mo T. Luong, Dung T. Nguyen, Marina V. Fedorova, Anna V. Valdokhina, Victoria P. Bulanenko, Vasiliy G. Akimkin, Lyudmila S. Karan   +15 more
openaire   +3 more sources

Filoviruses are ancient and integrated into mammalian genomes

BMC Evolutionary Biology, 2010
Background Hemorrhagic diseases from Ebolavirus and Marburgvirus (Filoviridae) infections can be dangerous to humans because of high fatality rates and a lack of effective treatments or vaccine.
Bruenn Jeremy, Leach Robert W, Taylor Derek J   +2 more
doaj   +1 more source

Maternal Immunization Using a Protein Subunit Vaccine Mediates Passive Immunity against Zaire ebolavirus in a Murine Model

Viruses, 2022
The Ebola virus has caused outbreaks in Central and West Africa, with high rates of morbidity and mortality. Clinical trials of recombinant virally vectored vaccines did not explicitly include pregnant or nursing women, resulting in a gap in knowledge of
Caitlin A. Williams, Teri Ann S. Wong, Aquena H. Ball, Michael M. Lieberman, Axel T. Lehrer   +4 more
doaj   +1 more source