Results 41 to 50 of about 4,627 (161)

The Mengla virus (Filoviridae: Dianlovirus)

Вопросы вирусологии
Introduction. Filoviruses associated with various species of pteropodid bats (Chiroptera: Pteropodidae) are traditionally regarded as potential causative agents of hemorrhagic fevers with epidemic potential.
Tatyana E. Sizikova, Vitaliy N. Lebedev, Sergey V. Borisevich   +2 more
doaj   +1 more source

Potential Vaccines and Post-Exposure Treatments for Filovirus Infections

Viruses, 2012
Viruses of the family Filoviridae represent significant health risks as emerging infectious diseases as well as potentially engineered biothreats. While many research efforts have been published offering possibilities toward the mitigation of filoviral ...
Gene G. Olinger, Brian M. Friedrich, John C. Trefry, Lisa E. Hensley, Anna N. Honko, Darci R. Smith, Julia E. Biggins   +6 more
doaj   +1 more source

Ebola hemorrhagic fever outbreaks: strategies for effective epidemic management, containment and control

Brazilian Journal of Infectious Diseases, 2015
Ebola hemorrhagic fever, caused by the highly virulent RNA virus of the filoviridae family, has become one of the world's most feared pathogens. The virus induces acute fever and death, often associated with hemorrhagic symptoms in up to 90% of infected ...
Gerald Amandu Matua, Dirk Mostert Van der Wal, Rozzano C. Locsin   +2 more
doaj   +1 more source

Differences in cynomolgus macaque populations used for infectious disease research

Animal Models and Experimental Medicine, Volume 9, Issue 2, Page 298-307, February 2026.
Cynomolgus macaques, a species of Old World primate native to southeastern and eastern Asia and the island of Mauritius, are one of the most important nonhuman primate models for infectious disease. Research into the population genetics of cynomolgus macaques has found significant differences between macaques native to different areas, particularly ...
Darcy Quist, Kimimuepigha Ebisine, Emma Kennedy, Stuart Dowall, Mike Dennis   +4 more
wiley   +1 more source

In Silico Identification of Antiviral Peptides as Potential Leads Against Sudan Ebolavirus VP‐40

BioMed Research International, Volume 2026, Issue 1, 2026.
The continued reemergence of Ebola virus epidemics remains a global health concern, largely due to limited therapeutic interventions. This study is aimed at identifying and characterizing antiviral peptides as potential lead candidates against the Sudan Ebola virus.
Boniface Omara, Kenedy Kiyimba, Fatoumata G. Fofana, Oudou Diabaté, Walter Odur, Daudi Jjingo, Jacob Stanley Iramiot, Peace Draleru, Joan Achia, Muhammad Shafiq, Zaheer Ul-Haq, Hedmon Okella, Steven Odongo, Swaran J. S. Flora   +13 more
wiley   +1 more source

Integrating Optimal Control and Economic Analysis to Inform Marburg Virus Response: A Comparison of Intervention Packages

Journal of Mathematics, Volume 2026, Issue 1, 2026.
Marburg virus disease is a severe hemorrhagic illness caused by filoviruses that kills roughly half of those it infects, yet no licensed vaccine or specific antiviral treatment currently exists. When an outbreak strikes a resource‐poor region, health officials face an agonizing question: which interventions offer the most protection for the least cost?
Raed Qahiti, Gizachew Kefelew Hailu, Ali H. Hakami, Ahmad Albaity, Shewafera Wondimagegnhu Teklu, Smritijit Sen   +5 more
wiley   +1 more source

Ebola Virus Disease Preparedness in Subnational Health Systems: A Readiness Assessment of Jinja District, Uganda

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Background Ebola virus disease (EVD) remains a significant public health threat in sub‐Saharan Africa. Jinja District in Uganda has experienced two EVD outbreaks in the recent past, first in November 2022 and again in February 2025, positioning it among the country’s EVD hotspots during Uganda’s eight recorded outbreaks.
Joseph Oposhia, Joseph M. Kungu, Peter Dyogo Nantamu, Josephine Namayanja, Charles A. B. Okuyo, Michael Mulowoza, Kenneth Kabali, Katushabe Edson, Peter Olupot-Olupot, Rajib Chowdhury   +9 more
wiley   +1 more source

Ebolavirus and Haemorrhagic Syndrome

Sultan Qaboos University Medical Journal, 2015
The Ebola virus is a highly virulent, single-stranded ribonucleic acid virus which affects both humans and apes and has fast become one of the world’s most feared pathogens. The virus induces acute fever and death, with haemorrhagic syndrome occurring in
Gerald A. Matua, Dirk M. Van der Wal, Rozzano C. Locsin   +2 more
doaj  

Experimental Vaccines for Prevention of Marburg Hemorrhagic Fever and Animal Models for Studying Pathogenesis

Проблемы особо опасных инфекций, 2018
Marburg fever is an acute natural-focal disease characterized by severe course, hemorrhagic syndrome, high level of contagiousness and lethality. The causative agent of the disease is the RNA-containing virus belonging to the family of filoviruses ...
N. V. Volkova, E. I. Kazachinskaya, D. N. Shcherbakov   +2 more
doaj   +1 more source

Remdesivir Use During Pregnancy: Findings From the Prospective COVID‐19 International Drug Pregnancy Registry and Narrative Literature Review

Journal of Pregnancy, Volume 2026, Issue 1, 2026.
Background and Aims Remdesivir (RDV), an inhibitor of coronavirus replication including SARS‐CoV‐2, has been approved for the treatment of COVID‐19. Nevertheless, its use during pregnancy lacks specific efficacy and safety data due to the exclusion of pregnant patients from clinical trials.
Diego F. Wyszynski, Cheryl Renz, Aprille Espinueva, Lee P. Shulman, EunYoung Lee, Andrew Fitzgibbon, Gina Brown, Karuna Sharma   +7 more
wiley   +1 more source