Bombali virus (Filoviridae: Orthoebolavirus: Orthoebolavirus bombaliense)
Introduction. Members of genus Orthoebolavirus of family Filoviridae cause severe hemorrhagic fever in humans with high fatality rates (up to 90%). The first outbreaks of disease caused by the members of genus Orthoebolavirus were registered in 1976 in ...
Tatiana E. Sizikova +2 more
doaj +2 more sources
Persistence and Organ Tropism of Filoviruses in Farmed European Perch (Perca fluviatilis). [PDF]
Journal of Fish Diseases, Volume 49, Issue 5, May 2026.
Perschthaler J +4 more
europepmc +2 more sources
Strategic Preparedness of Broad-Spectrum Antivirals for Rapid Response Towards Next Pandemics. [PDF]
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
N SR, Jin GW, Choy JH.
europepmc +2 more sources
Differences in cynomolgus macaque populations used for infectious disease research. [PDF]
Cynomolgus macaques, a species of Old World primate native to southeastern and eastern Asia and the island of Mauritius, are one of the most important nonhuman primate models for infectious disease. Research into the population genetics of cynomolgus macaques has found significant differences between macaques native to different areas, particularly ...
Quist D +4 more
europepmc +2 more sources
ICTV Virus Taxonomy Profile: Filoviridae [PDF]
Members of the family Filoviridae produce variously shaped, often filamentous, enveloped virions containing linear non-segmented, negative-sense RNA genomes of 15–19 kb. Several filoviruses (e.g., Ebola virus) are pathogenic for humans and are highly virulent.
Kuhn, Jens H +23 more
openaire +3 more sources
Unveiling Novel Viral Diversity, Biogeography, and Host Networks in Wildlife Through High-Throughput Sequencing Data Mining. [PDF]
Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Wang H +19 more
europepmc +2 more sources
Protease inhibitors targeting coronavirus and filovirus entry. [PDF]
In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases.
Agudelo, Juliet +10 more
core +1 more source
Virus specific antibody - based remedies for the urgent prevention and treatment of Ebola virus disease [PDF]
The Ebola virus (member of Ebolavirus genus Filoviridae family) is the etiologic agent of extremely hazard human disease with high mortality rates (up to 90%). The most important components of spectrum of therapeutics for special prophylactic and current
T E Sizikova +2 more
doaj +1 more source
Filovirus RefSeq Entries: Evaluation and Selection of Filovirus Type Variants, Type Sequences, and Names [PDF]
Sequence determination of complete or coding-complete genomes of viruses is becoming common practice for supporting the work of epidemiologists, ecologists, virologists, and taxonomists.
Andersen, Kristian G. +75 more
core +3 more sources
The West African ebola virus disease epidemic 2014–2015: A commissioned review
The first epidemic of Ebola haemorrhagic disease in West Africa is the largest and longest Ebola epidemic till date, where the outbreak notably involved three countries with distant spread to other countries.
S A Omilabu +3 more
doaj +1 more source

