Results 41 to 50 of about 11,589 (212)
Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis [PDF]
, 2017 Ebola virus (EBOV) is an enveloped negative-sense RNA virus that causes sporadic outbreaks with high case fatality rates. Ebola viral protein 30 (eVP30) plays a critical role in EBOV transcription initiation at the nucleoprotein (eNP) gene, with ...
Amarasinghe, Gaya K +6 more
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Estimating the reproduction number of Ebola virus (EBOV) during the 2014 outbreak in West Africa [PDF]
, 2014 The 2014 Ebola virus (EBOV) outbreak in West Africa is the largest outbreak of the genus Ebolavirus to date. To better understand the spread of infection in the affected countries, it is crucial to know the number of secondary cases generated by an ...
Althaus, Christian L.
core +2 more sources
Data Fitting and Scenario Analysis of Vaccination in the 2014 Ebola Outbreak in Liberia [PDF]
Osong Public Health and Research Perspectives, 2019 Objectives This study aimed to extend an epidemiological model (SEIHFR) to analyze epidemic trends, and evaluate intervention efficacy. Methods SEIHFR was modified to examine disease transmission dynamics after vaccination for the Ebola outbreak.
Zhifu Xie
doaj +1 more source
Filoviruses: Innate Immunity, Inflammatory Cell Death, and Cytokines
Pathogens, 2022 Filoviruses are a group of single-stranded negative sense RNA viruses. The most well-known filoviruses that affect humans are ebolaviruses and marburgviruses. During infection, they can cause life-threatening symptoms such as inflammation, tissue damage,
Jianlin Lu +2 more
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Seroprevalence of Ebola virus infection in Bombali District, Sierra Leone [PDF]
, 2017 A serosurvey of anti-Ebola Zaire virus nucleoprotein IgG prevalence was carried out among Ebola virus disease survivors and their Community Contacts in Bombali District, Sierra Leone. Our data suggest that the specie of Ebola virus (Zaire) responsible of
Antonella Minutolo +13 more
core +2 more sources
Ebolavirus: Infection, Vaccination and Control [PDF]
Molecular Genetics, Microbiology and Virology, 2021 Members of the genus Ebolavirus (family Filoviridae) are among the deadliest viral pathogens spread throughout the world with severe rate of mortality, at least 90% in some outbreaks. Their virions are filamentous and enveloped with enclosed negative-sense single-stranded RNA genome.
Ahad, Abdul +4 more
openaire +1 more source
Re-emerging infectious diseases: Ebola hemorrhagic fever [PDF]
Romanian Journal of Military Medicine, 2014 The spring of 2014 has brought a new calamity, the exotic infectious disease: Ebola Hemorrhagic Fever, which is caused by a highly contagious and pathogenic virus, transmitted directly by interpersonal contact or indirectly by common usage of objects ...
Lucia E. Ionescu +2 more
doaj
Development and Structural Analysis of Antibody Therapeutics for Filoviruses
Pathogens, 2022 The filoviruses, including ebolaviruses and marburgviruses, are among the world’s deadliest pathogens. As the only surface-exposed protein on mature virions, their glycoprotein GP is the focus of current therapeutic monoclonal antibody discovery efforts.
Xiaoying Yu, Erica Ollmann Saphire
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Ebolavirus and Haemorrhagic Syndrome
Sultan Qaboos University Medical Journal, 2015 The Ebola virus is a highly virulent, single-stranded ribonucleic acid virus which affects both humans and apes and has fast become one of the world's most feared pathogens. The virus induces acute fever and death, with haemorrhagic syndrome occurring in up to 90% of patients.
Gerald A. Matua +2 more
openaire +4 more sources
Virology Journal, 2018 Background The 2014/2015 Ebolavirus outbreak resulted in more than 28,000 cases and 11,323 reported deaths, as of March 2016. Domestic transmission of the Guinea strain associated with the outbreak occurred mainly in six African countries, and ...
Ameh S. James +4 more
doaj +1 more source