Results 31 to 40 of about 8,175 (207)

Ebolavirus vaccines for humans and apes [PDF]

Current Opinion in Virology, 2012
Because of high case fatality proportions, person-to-person transmission, and potential use in bioterrorism, the development of a vaccine against ebolavirus remains a top priority. Although no licensed vaccine or treatment against ebolavirus is currently available, progress in preclinical testing of countermeasures has been made.
Hugues, Fausther-Bovendo, Sabue, Mulangu, Nancy J, Sullivan   +2 more
openaire   +2 more sources

Epitope-based peptide vaccine against Bombali Ebolavirus viral protein 40: An immunoinformatics combined with molecular docking studies

Informatics in Medicine Unlocked, 2021
Bombali Ebolavirus belongs to the RNA group of viruses which causes lethal hemorrhagic fever with a high mortality rate. Despite these facts, yet there is no approved vaccine have been developed for the eradication of Bombali Ebolavirus infections ...
Mujahed I. Mustafa, Shaza W. Shantier, Miyssa I. Abdelmageed, Abdelrafie M. Makhawi   +3 more
doaj   +1 more source

Microarray sequencing results for repository ebolavirus samples.

, 2022
Microarray sequencing results for repository ebolavirus samples.
Moussa Kourout (12072040), Robert Duncan (29511), Gerardo Kaplan (3117903), Irina Tiper (12072037), Anjan Purkayastha (3727), Carolyn Fisher (640812), Krishnamurthy Konduru (3117906)   +6 more
core   +1 more source

Ebolavirus and Haemorrhagic Syndrome

Sultan Qaboos University Medical Journal, 2015
The Ebola virus is a highly virulent, single-stranded ribonucleic acid virus which affects both humans and apes and has fast become one of the world's most feared pathogens. The virus induces acute fever and death, with haemorrhagic syndrome occurring in up to 90% of patients.
Gerald A. Matua, Dirk M. Van der Wal, Rozzano C. Locsin   +2 more
openaire   +4 more sources

An adenovirus serotype 2-vectored ebolavirus vaccine generates robust antibody and cell-mediated immune responses in mice and rhesus macaques

Emerging Microbes and Infections, 2018
Ebolavirus vaccines based on several adenoviral vectors have been investigated in preclinical studies and clinical trials. The use of adenovirus serotype 2 as a vector for ebolavirus vaccine has not been reported.
Yupeng Feng, Chufang Li, Peiyu Hu, Qian Wang, Xuehua Zheng, Yongkun Zhao, Yi Shi, Songtao Yang, Changhua Yi, Ying Feng, Chunxiu Wu, Linbing Qu, Wei Xu, Yao Li, Caijun Sun, Fu Geroge Gao, Xianzhu Xia, Liqiang Feng, Ling Chen   +18 more
doaj   +1 more source

Taï Forest Virus Does Not Cause Lethal Disease in Ferrets

Microorganisms, 2021
Filoviruses are zoonotic, negative-sense RNA viruses, most of which are capable of causing severe disease in humans and nonhuman primates, often with high case fatality rates.
Zachary Schiffman, Feihu Yan, Shihua He, Kevin Tierney, Wenjun Zhu, Karla Emeterio, Huajun Zhang, Logan Banadyga, Xiangguo Qiu   +8 more
doaj   +1 more source

Flow cytometry evaluation of the rhesus monkey cellular immunity following the Zaire ebolavirus (Filoviridae; Ebolavirus: Zaire ebolavirus) experimental infection

Problems of Virology, 2021
Introduction. The outbreaks of the Zaire ebolavirus (ZE) disease (ZED) that have arisen in the last decade determine the need to study the infection pathogenesis, the formation of specific immunity forming as well as the development of effective preventive and therapeutic means.
G. V. Borisevich, S. L. Kirillova, I. V. Shatokhina, V. N. Lebedev, N. V. Shagarova, S. I. Syromyatnikova, A. F. Andrus, E. A. Koval’chuk, V. B. Kirillov, M. L. Bespalov, A. A. Petrov, A. V. Koval’chuk, V. B. Pantyukhov, D. A. Kutayev, S. V. Borisevich, S. L. Kuznetsov   +15 more
openaire   +4 more sources

Phylogenetic Analysis of Guinea 2014 EBOV Ebolavirus Outbreak [PDF]

, 2014
Members of the genus Ebolavirus have caused outbreaks of haemorrhagic fever in humans in Africa. The most recent outbreak in Guinea, which began in February of 2014, is still ongoing.
Rambaut, Andrew, Dudas, Gytis
core   +1 more source

Re-emerging infectious diseases: Ebola hemorrhagic fever [PDF]

Romanian Journal of Military Medicine, 2014
The spring of 2014 has brought a new calamity, the exotic infectious disease: Ebola Hemorrhagic Fever, which is caused by a highly contagious and pathogenic virus, transmitted directly by interpersonal contact or indirectly by common usage of objects ...
Lucia E. Ionescu, Gabriela V. Dumitrescu, Viorel Ordeanu   +2 more
doaj  

Data Fitting and Scenario Analysis of Vaccination in the 2014 Ebola Outbreak in Liberia [PDF]

Osong Public Health and Research Perspectives, 2019
Objectives This study aimed to extend an epidemiological model (SEIHFR) to analyze epidemic trends, and evaluate intervention efficacy. Methods SEIHFR was modified to examine disease transmission dynamics after vaccination for the Ebola outbreak.
Zhifu Xie
doaj   +1 more source