Results 31 to 40 of about 6,334 (171)
Problems of Virology, 2021 Introduction. The outbreaks of the Zaire ebolavirus (ZE) disease (ZED) that have arisen in the last decade determine the need to study the infection pathogenesis, the formation of specific immunity forming as well as the development of effective preventive and therapeutic means.
G. V. Borisevich +15 more
openaire +4 more sources
Emerging Microbes and Infections, 2018 Ebolavirus vaccines based on several adenoviral vectors have been investigated in preclinical studies and clinical trials. The use of adenovirus serotype 2 as a vector for ebolavirus vaccine has not been reported.
Yupeng Feng +18 more
doaj +1 more source
Taï Forest Virus Does Not Cause Lethal Disease in Ferrets
Microorganisms, 2021 Filoviruses are zoonotic, negative-sense RNA viruses, most of which are capable of causing severe disease in humans and nonhuman primates, often with high case fatality rates.
Zachary Schiffman +8 more
doaj +1 more source
Re-emerging infectious diseases: Ebola hemorrhagic fever [PDF]
Romanian Journal of Military Medicine, 2014 The spring of 2014 has brought a new calamity, the exotic infectious disease: Ebola Hemorrhagic Fever, which is caused by a highly contagious and pathogenic virus, transmitted directly by interpersonal contact or indirectly by common usage of objects ...
Lucia E. Ionescu +2 more
doaj
Data Fitting and Scenario Analysis of Vaccination in the 2014 Ebola Outbreak in Liberia [PDF]
Osong Public Health and Research Perspectives, 2019 Objectives This study aimed to extend an epidemiological model (SEIHFR) to analyze epidemic trends, and evaluate intervention efficacy. Methods SEIHFR was modified to examine disease transmission dynamics after vaccination for the Ebola outbreak.
Zhifu Xie
doaj +1 more source
Filoviruses: Innate Immunity, Inflammatory Cell Death, and Cytokines
Pathogens, 2022 Filoviruses are a group of single-stranded negative sense RNA viruses. The most well-known filoviruses that affect humans are ebolaviruses and marburgviruses. During infection, they can cause life-threatening symptoms such as inflammation, tissue damage,
Jianlin Lu +2 more
doaj +1 more source
Ebola Stigma and Its Impact on Outbreak Control: Lessons From Key Informant Interviews in Central Uganda. [PDF]
Trop Med Int HealthABSTRACT Objectives The 2022 outbreak of Sudan ebolavirus in central Uganda was the country's largest in two decades. It was accompanied by reports of stigma towards affected individuals, households and communities. The objectives of this study were to (1) describe how Ebola disease stigma emerged and manifested during the 2022 Sudan ebolavirus ...
Paterson A +9 more
europepmc +2 more sources
Development and Structural Analysis of Antibody Therapeutics for Filoviruses
Pathogens, 2022 The filoviruses, including ebolaviruses and marburgviruses, are among the world’s deadliest pathogens. As the only surface-exposed protein on mature virions, their glycoprotein GP is the focus of current therapeutic monoclonal antibody discovery efforts.
Xiaoying Yu, Erica Ollmann Saphire
doaj +1 more source
Virology Journal, 2018 Background The 2014/2015 Ebolavirus outbreak resulted in more than 28,000 cases and 11,323 reported deaths, as of March 2016. Domestic transmission of the Guinea strain associated with the outbreak occurred mainly in six African countries, and ...
Ameh S. James +4 more
doaj +1 more source
The Molecular Genetic Peculiarities of Genomic Structure of Members of the Ebolavirus Genus
Проблемы особо опасных инфекций, 2015 The molecular genetic peculiarities of genomic structure of the Ebolavirus genus members are viewed in the review. The Ebola virus disease outbreaks in West African countries constitute a threat not only for Africa, but for the whole world in view of ...
A. A. Petrov +8 more
doaj +1 more source