Results 51 to 60 of about 11,589 (212)

Need of surveillance response systems to combat Ebola outbreaks and other emerging infectious diseases in African countries [PDF]

open access: yes, 2014
There is growing concern in Sub-Saharan Africa about the spread of the Ebola virus disease (EVD), formerly known as Ebola haemorrhagic fever, and the public health burden that it ensues.
Emmanuel Ugwu   +2 more
core   +6 more sources

The Molecular Genetic Peculiarities of Genomic Structure of Members of the Ebolavirus Genus

open access: yesПроблемы особо опасных инфекций, 2015
The molecular genetic peculiarities of genomic structure of the Ebolavirus genus members are viewed in the review. The Ebola virus disease outbreaks in West African countries constitute a threat not only for Africa, but for the whole world in view of ...
A. A. Petrov   +8 more
doaj   +1 more source

[Ebola virus (Filoviridae: Ebolavirus: Zaire ebolavirus): fatal adaptation mutations].

open access: yesVoprosy virusologii, 2021
Ebola virus disease (EVD) (former Ebola hemorrhagic fever) is one of the most dangerous infectious diseases affecting humans and primates. Since the identification of the first outbreak in 1976, there have been more than 25 outbreaks worldwide, the largest of which escalated into an epidemic in 2014-2016 and caused the death of more than 11,000 people.
I. V. Dolzhikova   +3 more
openaire   +2 more sources

Presence and persistence of Ebola or Marburg virus in patients and survivors: A rapid systematic review [PDF]

open access: yes, 2016
Background: The 2013-15 Ebola outbreak was unprecedented due to sustainedtransmission within urban environments and thousands of survivors. In 2014 the World Health Organization stated that there was insufficient evidence to give definitive guidance ...
Brainard, Julii   +4 more
core   +3 more sources

Ebolavirus Classification Based on Natural Vectors [PDF]

open access: yesDNA and Cell Biology, 2015
According to the WHO, ebolaviruses have resulted in 8818 human deaths in West Africa as of January 2015. To better understand the evolutionary relationship of the ebolaviruses and infer virulence from the relationship, we applied the alignment-free natural vector method to classify the newest ebolaviruses.
Hui, Zheng   +5 more
openaire   +2 more sources

Newly discovered ebola virus associated with hemorrhagic fever outbreak in Uganda.

open access: yesPLoS Pathogens, 2008
Over the past 30 years, Zaire and Sudan ebolaviruses have been responsible for large hemorrhagic fever (HF) outbreaks with case fatalities ranging from 53% to 90%, while a third species, Côte d'Ivoire ebolavirus, caused a single non-fatal HF case.
Jonathan S Towner   +17 more
doaj   +1 more source

Immunogenicity and safety of Ebola virus vaccines in healthy adults: a systematic review and network meta-analysis

open access: yesHuman Vaccines & Immunotherapeutics, 2021
Clinical development of Ebola virus vaccines (EVV) was accelerated by the West African Ebola virus epidemic which remains the deadliest in history. To compare and rank the EVV according to their immunogenicity and safety.
Alhassane Diallo   +7 more
doaj   +1 more source

Proteo-Genomic Analysis Identifies Two Major Sites of Vulnerability on Ebolavirus Glycoprotein for Neutralizing Antibodies in Convalescent Human Plasma

open access: yesFrontiers in Immunology, 2021
Three clinically relevant ebolaviruses – Ebola (EBOV), Bundibugyo (BDBV), and Sudan (SUDV) viruses, are responsible for severe disease and occasional deadly outbreaks in Africa.
Pavlo Gilchuk   +24 more
doaj   +1 more source

Risks Posed by Reston, the Forgotten Ebolavirus [PDF]

open access: yes, 2016
Out of the five members of the Ebolavirus family, four cause lifethreatening disease, whereas the fifth, Reston virus (RESTV), is nonpathogenic in humans. The reasons for this discrepancy remain unclear. In this review, we analyze the currently available
Arran Hamlet   +5 more
core   +2 more sources

Structural Basis of Pan-Ebolavirus Neutralization by an Antibody Targeting the Glycoprotein Fusion Loop

open access: yesCell Reports, 2018
Summary: Monoclonal antibodies (mAbs) with pan-ebolavirus cross-reactivity are highly desirable, but development of such mAbs is limited by a lack of a molecular understanding of cross-reactive epitopes.
Charles D. Murin   +5 more
doaj   +1 more source

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