Results 61 to 70 of about 7,952 (205)
ABSTRACT The coupling of replication and encapsidation in the bipartite plant virus, cowpea mosaic virus (CPMV), has been used to specifically incorporate designer RNA molecules into viral particles via transient expression in Nicotiana benthamiana. This is achieved by placing the desired RNA sequence between the 5′ and 3′ UTRs of CPMV RNA‐2 so that ...
H. Peyret +5 more
wiley +1 more source
Phylogenetic Analysis of Guinea 2014 EBOV Ebolavirus Outbreak [PDF]
Members of the genus Ebolavirus have caused outbreaks of haemorrhagic fever in humans in Africa. The most recent outbreak in Guinea, which began in February of 2014, is still ongoing.
Rambaut, Andrew, Dudas, Gytis
core +1 more source
Ebola virus disease outbreak in Korea: use of a mathematical model and stochastic simulation to estimate risk [PDF]
OBJECTIVES According to the World Health Organization, there have been frequent reports of Ebola virus disease (EVD) since the 2014 EVD pandemic in West Africa. We aim to estimate the outbreak scale when an EVD infected person arrives in Korea.
Youngsuk Ko +4 more
doaj +1 more source
In Silico Identification of Antiviral Peptides as Potential Leads Against Sudan Ebolavirus VP‐40
The continued reemergence of Ebola virus epidemics remains a global health concern, largely due to limited therapeutic interventions. This study is aimed at identifying and characterizing antiviral peptides as potential lead candidates against the Sudan Ebola virus.
Boniface Omara +13 more
wiley +1 more source
Discovery of an Ebolavirus-Like Filovirus in Europe
(Uploaded by Plazi for the Bat Literature Project) Filoviruses, amongst the most lethal of primate pathogens, have only been reported as natural infections in sub-Saharan Africa and the Philippines. Infections of bats with the ebolaviruses and marburgviruses do not appear to be associated with disease.
Negredo, Ana +16 more
openaire +9 more sources
Inclusion Bodies Are a Site of Ebolavirus Replication [PDF]
ABSTRACT Inclusion bodies are a characteristic feature of ebolavirus infections in cells. They contain large numbers of preformed nucleocapsids, but their biological significance has been debated, and they have been suggested to be aggregates of viral proteins without any further biological function.
Thomas, Hoenen +9 more
openaire +2 more sources
Potent neutralizing monoclonal antibodies against Ebola virus isolated from vaccinated donors
Ebola virus (EBOV) can cause severe hemorrhagic fever in humans, and no approved treatment is currently available. Although several antibodies have achieved good protection in animal models, the potential emerging isolates of ebolavirus and the unknown ...
Pengfei Fan +12 more
doaj +1 more source
In 2014, Ebola virus (EBOV) was identified as the etiological agent of a large and still expanding outbreak of Ebola virus disease (EVD) in West Africa and a much more confined EVD outbreak in Middle Africa.
Jens H. Kuhn +43 more
doaj +1 more source
A Scoping Review of Machine Learning Applications Across Epidemiological Stages of Zoonotic Disease
Emerging zoonotic diseases represent a significant threat to global health. While machine learning (ML) holds promise for their management, a comprehensive understanding of how these technologies are applied across the entire animal‐to‐human transmission pathway is lacking.
Yinsheng Zhang +9 more
wiley +1 more source
An Interagency Collaboration to Facilitate Development of Filovirus Medical Countermeasures
The Filovirus Animal Non-Clinical Group (FANG) is a US interdepartmental and interagency group established to support and facilitate the advanced development of filovirus Medical Countermeasures (MCM), both vaccines and therapeutics.
Edwin O. Nuzum, Nicole Kilgore
doaj +1 more source

