Results 81 to 90 of about 6,334 (171)
Viruses, 2014 Sequence determination of complete or coding-complete genomes of viruses is becoming common practice for supporting the work of epidemiologists, ecologists, virologists, and taxonomists.
Jens H. Kuhn +75 more
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Reston Ebolavirus Antibodies in Bats, the Philippines
Emerging Infectious Diseases, 2011 Reston Ebolavirus Antibodies in Bats, the PhilippinesPara el editor: Los filovirus causan fiebre hemorrágica altamente letal en humanos y primates no humanos, a excepción del Reston Ebolavirus (REBOV), que causa fiebre hemorrágica severa en macacos (1,2). Las epizootias de REBOV entre macacos cynomolgus ocurrieron en 1989, 1990, 1992 y 1996 (2) y entre
Satoshi Taniguchi +17 more
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Structural Basis for Differential Neutralization of Ebolaviruses
Viruses, 2012 There are five antigenically distinct ebolaviruses that cause hemorrhagic fever in humans or non-human primates (Ebola virus, Sudan virus, Reston virus, Taï Forest virus, and Bundibugyo virus).
John M. Dye +11 more
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Ebolavirus and evidence-based speculations.
The new microbiologica, 2016 .
Focosi, Daniele +2 more
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Characterization of Sudan Ebolavirus infection in ferrets
Oncotarget, 2017 Sudan virus (SUDV) outbreaks in Africa are highly lethal; however, the development and testing of novel antivirals and vaccines for this virus has been limited by a lack of suitable animal models. Non-human primates (NHP) remain the gold standard for modeling filovirus disease, but they are not conducive to screening large numbers of experimental ...
Kroeker, Andrea +5 more
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Testing New Hypotheses Regarding Ebolavirus Reservoirs
Viruses, 2016 Despite a relatively long search for the origin of ebolaviruses, their reservoirs remain elusive. Researchers might have to consider testing alternative hypotheses about how these viruses persist and emerge to advance ebolavirus research.
Siv Aina Jensen Leendertz
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Standardization of the Filovirus Plaque Assay for Use in Preclinical Studies
Viruses, 2012 The filovirus plaque assay serves as the assay of choice to measure infectious virus in a cell culture, blood, or homogenized tissue sample. It has been in use for more than 30 years and is the generally accepted assay used to titrate virus in samples ...
Gene G. Olinger +10 more
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Immunotherapeutics for Ebola Virus Disease: Hope on the Horizon
Biologics: Targets & Therapy, 2021 Kyle L O’Donnell, Andrea Marzi Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USACorrespondence: Andrea Marzi Email marzia@niaid.nih ...
O'Donnell KL, Marzi A
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Design and characterization of protective pan-ebolavirus and pan-filovirus bispecific antibodies.
PLoS PathogensMonoclonal antibodies (mAbs) are an important class of antiviral therapeutics. MAbs are highly selective, well tolerated, and have long in vivo half-life as well as the capacity to induce immune-mediated virus clearance.
Ariel S Wirchnianski +21 more
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PathogensSequence analysis of the Zaire ebolavirus (EBOV) polymerase (L gene) mRNA, using online tools, identified a highly ranked −1 programmed ribosomal frameshift (FS) signal including an ideal slippery sequence heptamer (UUUAAAA), with an overlapping coding ...
David B. Stubbs +2 more
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