Taï Forest Virus Does Not Cause Lethal Disease in Ferrets [PDF]
Microorganisms, 2021 Filoviruses are zoonotic, negative-sense RNA viruses, most of which are capable of causing severe disease in humans and nonhuman primates, often with high case fatality rates.
Zachary Schiffman +8 more
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Single-dose VSV-based vaccine protects cynomolgus macaques from disease after Taï Forest virus infection [PDF]
Emerging Microbes and Infections, 2023 Taï Forest virus (TAFV) is a lesser-known ebolavirus that causes lethal infections in chimpanzees and is responsible for a single human case. Limited research has been done on this human pathogen; however, with the recent emergence of filoviruses in West
Paige Fletcher +11 more
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Pathogenic differences of cynomolgus macaques after Taï Forest virus infection depend on the viral stock propagation. [PDF]
PLoS PathogensTaï Forest virus (TAFV) is a negative-sense RNA virus in the Filoviridae family. TAFV has caused only a single human infection, but several disease outbreaks in chimpanzees have been linked to this virus.
Paige Fletcher +10 more
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Mucosal Taï Forest virus infection causes disease in ferrets. [PDF]
PLoS PathogensThe filovirus Taï Forest virus (TAFV) caused a single human case of infection originating from a chimpanzee outbreak, demonstrating that humans are susceptible to TAFV infection.
Paige Fletcher +8 more
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Presence and Persistence of Ebola or Marburg Virus in Patients and Survivors: A Rapid Systematic Review. [PDF]
PLoS Neglected Tropical Diseases, 2016 BackgroundThe 2013-15 Ebola outbreak was unprecedented due to sustained transmission within urban environments and thousands of survivors. In 2014 the World Health Organization stated that there was insufficient evidence to give definitive guidance about
Julii Brainard +4 more
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Filovirus RefSeq Entries: Evaluation and Selection of Filovirus Type Variants, Type Sequences, and Names [PDF]
Viruses, 2014 Sequence determination of complete or coding-complete genomes of viruses is becoming common practice for supporting the work of epidemiologists, ecologists, virologists, and taxonomists.
Jens H. Kuhn +75 more
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STAT-1 Knockout Mice as a Model for Wild-Type Sudan Virus (SUDV)
Viruses, 2021 Currently there is no FDA-licensed vaccine or therapeutic against Sudan ebolavirus (SUDV) infections. The largest ever reported 2014–2016 West Africa outbreak, as well as the 2021 outbreak in the Democratic Republic of Congo, highlight the critical need ...
Olivier Escaffre +12 more
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npj VirusesFew insect-specific alphaviruses (ISA) have been discovered, with even fewer culturable to facilitate full characterisation. Here, we report the recovery of an infectious clone of Yada Yada virus (YYV)—a virus previously only detected by metagenomic ...
Mikaela G. Bell +12 more
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Nature CommunicationsThe natural reservoir of Ebola virus (EBOV), agent of a zoonosis burdening several African countries, remains unidentified, albeit evidence points towards bats.
S. A. Riesle-Sbarbaro +17 more
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Homologous and heterologous protection of nonhuman primates by Ebola and Sudan virus-like particles.
PLoS ONE, 2015 Filoviruses cause hemorrhagic fever resulting in significant morbidity and mortality in humans. Several vaccine platforms that include multiple virus-vectored approaches and virus-like particles (VLPs) have shown efficacy in nonhuman primates.
Kelly L Warfield +9 more
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