Results 91 to 100 of about 8,175 (207)
ABSTRACT Objectives The 2022 outbreak of Sudan ebolavirus in central Uganda was the country's largest in two decades. It was accompanied by reports of stigma towards affected individuals, households and communities. The objectives of this study were to (1) describe how Ebola disease stigma emerged and manifested during the 2022 Sudan ebolavirus ...
Amy Paterson +9 more
wiley +1 more source
Abstract Background and Objectives The coronavirus disease 2019 (COVID‐19) pandemic necessitated various therapeutic approaches, including convalescent plasma (CP) administration. The administration timing of COVID‐19 CP (CCP), antibody specificity and quantity were identified as crucial factors for therapeutic success.
Sandra Laner‐Plamberger +9 more
wiley +1 more source
Ebola, previously known as Ebola hemorrhagic fever, is a severe, often fatal disease in humans and nonhuman primates (such as monkeys, gorillas, and chimpanzees).Ebola is a rare and deadly disease caused by infection with a virus of the family ...
core
Zaire ebolavirus entry is CatB mediated.
Vero E6 cells were treated prior to infection for one hour with inhibitors directed against the indicated cathepsin(s) or endosomal acidification (BafA1).
Andrea Marzi (146489) +2 more
core +1 more source
Resurgence of Ebola in Uganda: Response Strategies, Lessons Learned, and Future Directions
ABSTRACT Introduction The recent resurgence of Ebola virus disease (EVD), specifically the Sudan virus strain, in Uganda highlights the ongoing threat of emerging infectious diseases. This article aims to analyze the multifaceted factors contributing to this resurgence, evaluate the public health impact, and assess the effectiveness of response ...
Majani Edward +3 more
wiley +1 more source
Discrimination of five Ebolavirus species through HRM genotyping analysis.
Following the completion of PCR, the Tm of probe hybridization to the targets was determined by high-resolution melting (HRM) curve analysis as the peak of the second derivative of the fluorescence released during a temperature increase from 38°C to 85°C.
Guangwu Lu (745819) +6 more
core +1 more source
Sequence determination of complete or coding-complete genomes of viruses is becoming common practice for supporting the work of epidemiologists, ecologists, virologists, and taxonomists.
Jens H. Kuhn +75 more
doaj +1 more source
Cryo-EM structure of Sudan ebolavirus glycoprotein complexed with its human endosomal receptor NPC1
Sudan ebolavirus (SUDV), like Ebola ebolavirus (EBOV), poses a significant threat to global health and security due to its high lethality. However, unlike EBOV, there are no approved vaccines or treatments for SUDV, and its structural interaction with ...
Fan Bu +5 more
doaj +1 more source
Ebolavirus vaccines based on several adenoviral vectors have been investigated in preclinical studies and clinical trials. The use of adenovirus serotype 2 as a vector for ebolavirus vaccine has not been reported.
Chufang Li (422883) +18 more
core +1 more source
Structural Basis for Differential Neutralization of Ebolaviruses
There are five antigenically distinct ebolaviruses that cause hemorrhagic fever in humans or non-human primates (Ebola virus, Sudan virus, Reston virus, Taï Forest virus, and Bundibugyo virus).
John M. Dye +11 more
doaj +1 more source

