Results 91 to 100 of about 11,589 (212)

RIG-I activation inhibits ebolavirus replication

Virology, 2009
Hemorrhagic fever viruses are associated with rapidly progressing severe disease with high case fatality, making them of public health and biothreat importance. Effective antivirals are not available for most of the members of this diverse group of viruses. A broad spectrum strategy for antiviral development would be very advantageous. Perhaps the most
Spiropoulou, Christina F., Ranjan, Priya, Pearce, Melissa B., Sealy, Tara K., Albariño, César G., Gangappa, Shivaprakash, Fujita, Takashi, Rollin, Pierre E., Nichol, Stuart T., Ksiazek, Thomas G., Sambhara, Suryaprakash   +10 more
openaire   +2 more sources

Stable SARS‐CoV‐2 antibody levels and functionality in serum and COVID‐19 convalescent plasma after long‐term storage

Vox Sanguinis, Volume 120, Issue 8, Page 784-792, August 2025.
Abstract Background and Objectives The coronavirus disease 2019 (COVID‐19) pandemic necessitated various therapeutic approaches, including convalescent plasma (CP) administration. The administration timing of COVID‐19 CP (CCP), antibody specificity and quantity were identified as crucial factors for therapeutic success.
Sandra Laner‐Plamberger, Anita Siller, Wanda Lauth, Jan Marco Kern, Lenka Baskova, Nina Held, Orkan Kartal, Harald Schennach, Eva Rohde, Christoph Grabmer   +9 more
wiley   +1 more source

Plant phenology supports the multi-emergence hypothesis for ebola spillover events [PDF]

, 2017
Ebola virus disease outbreaks in animals (including humans and great apes) start with sporadic host switches from unknown reservoir species. The factors leading to such spillover events are little explored.
Douglas, Noah E., Isokpehi, Raphael D., Johnson, Brianna, McGill, Ayana, Sivasundaram, Seenith, Wollenberg Valero, Katharina C., Wootson, Kiara   +6 more
core   +1 more source

Factores pronósticos clínicos determinantes en la supervivencia de pacientes con el virus Ébola

Revista Cubana de Medicina Militar, 2020
Introducción: La enfermedad por el virus del Ébola presenta una elevada letalidad, por lo cual resulta de gran interés la realización de investigaciones que aborden las manifestaciones clínicas que pudieran ser factores pronósticos de supervivencia ...
Osvaldo Miranda Gómez, Carlos Manuel Castro Baras, Yoel Alberto Fleites Alonso, José Eduardo Díaz Gómez, Yanetsi Contreras Olive, Sara Anneris Urgellés Carrera   +5 more
doaj   +2 more sources

A Bayesian analysis of birth pulse effects on the probability of detecting Ebola virus in fruit bats

Peer Community Journal
Since 1976 various species of Ebolavirus have caused a series of zoonotic outbreaks and public health crises in Africa. Bats have long been hypothesised to function as important hosts for ebolavirus maintenance, however the transmission ecology for these
Pleydell, David R.J., Ndong Bass, Innocent, Mba Djondzo, Flaubert Auguste, Meta Djomsi, Dowbiss, Kouanfack, Charles, Peeters, Martine, Cappelle, Julien   +6 more
doaj   +1 more source

Risk assessment of Ebola Reston virus in humans in the Philippines

Western Pacific Surveillance and Response, 2019
Objective: There have been five documented outbreaks of Ebola Reston virus (RESTV) in animals epidemiologically linked to the Philippines. This assessment was conducted to determine the risk of RESTV occurring in humans in the Philippines and its ...
Johnette A Peñas, Mary Elizabeth Miranda, Vikki Carr de los Reyes, Ma. Nemia L Sucaldito, Rio L Magpantay   +4 more
doaj   +1 more source

Correspondence of Neutralizing Humoral Immunity and CD4 T Cell Responses in Long Recovered Sudan Virus Survivors. [PDF]

, 2016
Robust humoral and cellular immunity are critical for survival in humans during an ebolavirus infection. However, the interplay between these two arms of immunity is poorly understood.
Cose, Stephen, Dye, John M, Egesa, Moses, Eskira, Yael, Fedida-Metula, Shlomit, Herbert, Andrew S, Kuehne, Ana I, Lewis, Eli C, Lobel, Leslie, Lutwama, Julius Julian, Ochayon, David E, Sobarzo, Ariel, Stonier, Spencer W, Tali, Neta, Yavelsky, Victoria   +14 more
core   +2 more sources

Land Use Change and Infectious Disease Emergence

Reviews of Geophysics, Volume 63, Issue 2, June 2025.
Abstract Major infectious diseases threatening human health are transmitted to people from animals or by arthropod vectors such as insects. In recent decades, disease outbreaks have become more common, especially in tropical regions, including new and emerging infections that were previously undetected or unknown. Even though there is growing awareness
M. Cristina Rulli, Paolo D’Odorico, Nikolas Galli, Reju S. John, Renata L. Muylaert, Monia Santini, David T. S. Hayman   +6 more
wiley   +1 more source

Process Intensification for Recombinant Marburg Virus Glycoprotein Production Using Drosophila S2 Cells

Engineering in Life Sciences, Volume 25, Issue 5, May 2025.
ABSTRACT Marburg marburgvirus (MARV) is a highly virulent human pathogen with limited therapeutic options. Recombinant MARV glycoprotein (GP) produced in Drosophila Schneider 2 (S2) cells has been extensively investigated as potential vaccine antigen with promising efficacy demonstrated in nonhuman primate models.
Sven Göbel, Ludwig Mayerlen, Isabelle Yazel Eiser, Lisa Fichtmueller, David Clements, Udo Reichl, Yvonne Genzel, AxelT. Lehrer   +7 more
wiley   +1 more source

Comparative Analysis of the Sequenced Zaire ebolavirus Samples from the Republic of Guinea

Проблемы особо опасных инфекций, 2015
An unprecedented on its scale Ebola fever epidemic, caused by Zaire ebolavirus, has been registered in the territory of West Africa in 2014-2015. The virus quickly spread from the Republic of Guinea into the neighboring countries.
Ya. M. Krasnov, V. A. Safronov, N. Yu. Nosov, V. V. Kutyrev, A. Yu. Popova   +4 more
doaj   +1 more source