Discovery of an Ebolavirus-Like Filovirus in Europe
PLoS Pathogens, 2011 Filoviruses, amongst the most lethal of primate pathogens, have only been reported as natural infections in sub-Saharan Africa and the Philippines. Infections of bats with the ebolaviruses and marburgviruses do not appear to be associated with disease.
Negredo, Anabel +15 more
openaire +8 more sources
Neglected Dimensions of Global Security: The Global Health Risk Framework Commission [PDF]
, 2016 The world has experienced global health crises ranging from novel influenzas (H5N1 and H1N1) and coronaviruses (SARS and MERS) to the Ebola and Zika viruses.
Gostin, Lawrence O. +2 more
core +1 more source
The interplay between viral-derived miRNAs and host immunity during infection [PDF]
, 2019 MicroRNAs are short non-coding RNAs that play a crucial role in the regulation of gene expression during cellular processes. The host-encoded miRNAs are known to modulate the antiviral defense during viral infection.
Ingle, Harshad +3 more
core +1 more source
Isolation of Angola-like Marburg virus from Egyptian rousette bats from West Africa. [PDF]
, 2020 Marburg virus (MARV) causes sporadic outbreaks of severe Marburg virus disease (MVD). Most MVD outbreaks originated in East Africa and field studies in East Africa, South Africa, Zambia, and Gabon identified the Egyptian rousette bat (ERB; Rousettus ...
Amara, Emmanuel +49 more
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Immunotherapeutics for Ebola Virus Disease: Hope on the Horizon
Biologics: Targets & Therapy, 2021 Kyle L O’Donnell, Andrea Marzi Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USACorrespondence: Andrea Marzi Email marzia@niaid.nih ...
O'Donnell KL, Marzi A
doaj
Design and characterization of protective pan-ebolavirus and pan-filovirus bispecific antibodies.
PLoS PathogensMonoclonal antibodies (mAbs) are an important class of antiviral therapeutics. MAbs are highly selective, well tolerated, and have long in vivo half-life as well as the capacity to induce immune-mediated virus clearance.
Ariel S Wirchnianski +21 more
doaj +1 more source
Computational prediction and identification of miRNAs in ssRNA viruses [PDF]
, 2014 MiRNAs are conserved endogenous small non-coding RNA mols. play a very important role in posttranscriptional regulation of gene by binding to mRNA.miRNAs have been identified in plants, animals, invertebrates and even in viruses.
Padmashree, D., Ramachandra Swamy, N.
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Cartographie des zones à risque de transmission du virus Ebola en Guinée forestière par la méthode d'évaluation multicritère spatialisée [PDF]
, 2019 La maladie d'Ebola est une maladie infectieuse virale émergente, d'origine zoonotique, responsable d'épidémies importantes. Les cartes de risque de transmission peuvent aider à la surveillance pour prévenir des futures épidémies.
Lee Cruz, Larisa
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PathogensSequence analysis of the Zaire ebolavirus (EBOV) polymerase (L gene) mRNA, using online tools, identified a highly ranked −1 programmed ribosomal frameshift (FS) signal including an ideal slippery sequence heptamer (UUUAAAA), with an overlapping coding ...
David B. Stubbs +2 more
doaj +1 more source
Amiodarone and metabolite MDEA inhibit Ebola virus infection by interfering with the viral entry process [PDF]
, 2017 Ebola virus disease (EVD) is one of the most lethal transmissible infections characterized by a high fatality rate, and a treatment has not been developed yet.
Baritussio, Aldo +10 more
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