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Modular Polymerase Synthesis and Internal Protein Domain Swapping via Dual Opposed Frameshifts in the Ebola Virus L Gene

Pathogens
Sequence analysis of the Zaire ebolavirus (EBOV) polymerase (L gene) mRNA, using online tools, identified a highly ranked −1 programmed ribosomal frameshift (FS) signal including an ideal slippery sequence heptamer (UUUAAAA), with an overlapping coding ...
David B. Stubbs, Jan A. Ruzicka, Ethan W. Taylor +2 more
doaj +1 more source

MAF induction by Ebolavirus.

We studied Ebolavirus infection transcriptome-wide across multiple systems to monitor transcriptional dynamics following controlled infection. We report here induction of the nuclear factor MAF in cells following infection with Ebolavirus: in primary human hepatocytes, and in hepatocytes derived from induced pluripotent stem cells.
openaire +1 more source

Production and Characterisation of Monoclonal Antibodies to Ebolavirus Nucleoprotein and their Application in Development of a Rapid Antigen Detection Test

, 2014
Viruses belonging to Filoviridae family, namely ebolaviruses and marburgviruses, cause filoviral haemorrhagic fever (FHF), resulting in case fatality rates of up to 90 percent depending on the virus species and strain.
Changula, Katendi
core

Maladie à virus Ebola. [PDF]

CMAJ
Billick MJ, Silverstein WK, Bogoch II.
europepmc +1 more source

Ebola Virus Disease in Pregnancy: Maternal-Fetal Outcomes, Vertical Transmission, and Implications for Vaccination-A Narrative Review. [PDF]

J Clin Med
Hashim KNH, Mustafa HM, Adam I.
europepmc +1 more source

The Re-Emergence of Bundibugyo Ebolavirus in Uganda and the Democratic Republic of Congo: Epidemiological Drivers, Response Strategies, and Implications for Global Health Security. [PDF]