Results 291 to 300 of about 272,522 (346)

Establishment of a mouse model for ischaemic heart failure induced by coronary microembolization via left ventricular oil injection

open access: yesExperimental Physiology, EarlyView.
Abstract Over the past three decades, there has been a steady increase in clinical attention to ischaemic heart failure caused by coronary microembolization. Nonetheless, a suitable mouse model for studying this condition remains limited. In the present study, we developed a mouse model of coronary microembolization‐induced ischaemic heart failure by ...
Lang Pei   +10 more
wiley   +1 more source

ZFP36 inhibits the pro‐apoptotic effects of transforming growth factor β1 on mitral valve interstitial cells via the GTP‐binding protein 6 pathway in mitral valve prolapse

open access: yesExperimental Physiology, EarlyView.
Abstract The objective of this work was to investigate the role of ZFP36 in mitral valve prolapse (MVP). Mitral valve and plasma were collected to assess the expression of ZFP36, transforming growth factor β (TGF‐β), collagen and elastin and apoptosis rates.
Meng Zhao   +9 more
wiley   +1 more source

Cardioprotection via vagus nerve stimulation preconditioning: Reducing ischaemia–reperfusion injury and arrhythmic risk

open access: yesExperimental Physiology, EarlyView.
Abstract Acute myocardial infarction is a leading cause of morbidity and mortality, with ischaemia–reperfusion (I/R) injury exacerbating myocardial damage. Vagus nerve stimulation (VNS) has been reported to exert cardioprotective effects, but its efficacy in preconditioning against I/R injury requires further investigation.
Feng Hu   +10 more
wiley   +1 more source

Cardiac‐specific Kv1.1 deficiency alters cardiomyocyte electrophysiology without modifying overall cardiac function or arrhythmia susceptibility

open access: yesExperimental Physiology, EarlyView.
Abstract The leading cause of epilepsy‐related mortality is sudden unexpected death in epilepsy (SUDEP), resulting from seizure‐induced cardiorespiratory arrest by mechanisms that remain unresolved. Mutations in ion channel genes expressed in both brain and heart represent SUDEP risk factors because they can disrupt neural and cardiac rhythms ...
Kelsey Halvorson   +11 more
wiley   +1 more source

Sudden cardiac death in hyperthrophic cardiomyopathy: Comparison of predictive models. [PDF]

open access: yesTunis Med
Bayar MF   +5 more
europepmc   +1 more source

Sudden Cardiac Death in Childhood: Peaks in Teenagers. [PDF]

open access: yesCirc Arrhythm Electrophysiol
Westaby JD, Sheppard MN.
europepmc   +1 more source

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