Results 101 to 110 of about 3,347,409 (388)
Modifier genes for sudden cardiac death
European Heart Journal, 2018 Genetic conditions, even those associated with identical gene mutations, can present with variable clinical manifestations. One widely accepted explanation for this phenomenon is the existence of genetic factors capable of modifying the consequences of ...
P. Schwartz, L. Crotti, A. George
semanticscholar +1 more source
Advanced Science, EarlyView.This study reveals that ADAR1, an RNA‐editing enzyme, fine‐tunes immune responses in the placenta by preventing the accumulation of immunogenic double‐stranded RNAs (dsRNAs) from interferon‐stimulated genes. The loss of ADAR1 in the placenta leads to excessive interferon signaling restricted to the junctional zone, disrupting placental development and ...
Xiaogang Chen +7 more
wiley +1 more source
Long-term major events after hospital discharge for out-of-hospital cardiac arrest
Annals of Intensive CareBackground Cardiac arrest remains a global health issue with limited data on long-term outcomes, particularly regarding recurrent cardiovascular events in patients surviving out-of-hospital cardiac arrest. (OHCA).
Sofia Ortuno +12 more
doaj +1 more source
iScienceSummary: Genetic analysis identified the cause of the disease in inherited arrhythmogenic syndromes. A clinically actionable genetic diagnosis requires an accurate interpretation following the current guidelines. Practically half of the genetic diagnoses
Estefanía Martínez-Barrios +14 more
doaj +1 more source
Quantum decoherence in noninertial frames
, 2010 Quantum decoherence, which appears when a system interacts with its environment in an irreversible way, plays a fundamental role in the description of quantum-to-classical transitions and has been successfully applied in some important experiments. Here,
D. Bouwmeester +7 more
core +1 more source
Efficacy of pimobendan in the prevention of congestive heart failure or sudden death in doberman pinschers with preclinical dilated cardiomyopathy (the PROTECT study) [PDF]
, 2012 <p>Background: The benefit of pimobendan in delaying the progression of preclinical dilated cardiomyopathy (DCM) in Dobermans is not reported.</p> <p>Hypothesis: That chronic oral administration of pimobendan to Dobermans with ...
Boswood, A. +15 more
core +1 more source
Identifying Tipping Points during Healthy Brain Aging through Single‐Nucleus Transcriptomic Analysis
Advanced Science, EarlyView.This study applies single‐nucleus transcriptomics and systems dynamics to uncover nonlinear aging patterns in healthy human brains. By introducing dynamic network biomarker theory, the authors identify a critical tipping point at ages 56–60 during aging, and highlight glial instability as a key mediator.
Peiru Wu +9 more
wiley +1 more source