Results 41 to 50 of about 21,208 (196)

SUDEP and mortality in developmental and epileptic encephalopathies: A meta‐analysis of randomized clinical trials and extension studies

Epilepsia, EarlyView.
Abstract Objective Developmental and epileptic encephalopathies (DEEs) are associated with high premature mortality and increased risk of sudden unexpected death in epilepsy (SUDEP). However, epidemiological data remain limited, particularly for specific syndromes such as Dravet syndrome (DS), Lennox–Gastaut syndrome (LGS), and infantile epileptic ...
Pierludovico Moro, Maria Sole Borioni, Adolfo Mazzeo, Enrico Cocchi, Carlo Di Bonaventura, Emanuele Cerulli Irelli   +5 more
wiley   +1 more source

A proof-of-concept study to construct Bayesian network decision models for supporting the categorization of sudden unexpected infant death

Scientific Reports, 2022
Sudden infant death syndrome (SIDS) remains a leading cause of infant death in high-income countries. Supporting models for categorization of sudden unexpected infant death into SIDS/non-SIDS could reduce mortality.
Hideki Hamayasu, Masashi Miyao, Chihiro Kawai, Toshio Osamura, Akira Yamamoto, Hirozo Minami, Hitoshi Abiru, Keiji Tamaki, Hirokazu Kotani   +8 more
doaj   +1 more source

Comparative assessment of artificial intelligence chatbots' performance in responding to healthcare professionals' and caregivers' questions about Dravet syndrome

Epilepsia Open, EarlyView.
Abstract Objective Artificial intelligence chatbots have been a game changer in healthcare, providing immediate, round‐the‐clock assistance. However, their accuracy across specific medical domains remains under‐evaluated. Dravet syndrome remains one of the most challenging epileptic encephalopathies, with new data continuously emerging in the ...
Joana Jesus‐Ribeiro, Eugenia Roza, Bárbara Oliveiros, Joana Barbosa Melo, Mar Carreño   +4 more
wiley   +1 more source

Epilepsy syndromes classification

Epilepsia Open, EarlyView.
Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell, Nicola Specchio, Rima Nabbout, Phillip L. Pearl, Kate Riney   +4 more
wiley   +1 more source

Effect on parental’s cannabis consumption on the risk of sudden infant death syndrome: a systematic review [PDF]

Revista Brasileira de Saúde Materno Infantil
Objectives: to analyze and synthesize the available evidence on the effect of parental cannabis use on the risk of sudden infant death syndrome (SIDS). Methods: a systematic review was conducted in PubMed/MEDLINE, Embase, Scopus, Web of Science, and the
Lara Lobão Campos Bignoto, Paula da Costa Fernandes, Ana Cecília Finamore Bastida, Vitor Fernandes Alvim, Sabrine Teixeira Ferraz Grunewald   +4 more
doaj   +1 more source

New insights into epileptic spasm generation and treatment from the TTX animal model

Epilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann, Carlos J. Ballester‐Rosado, Chih‐Hong Lee   +2 more
wiley   +1 more source

International time trends in sudden unexpected infant death, 1969–2012

BMC Pediatrics, 2020
Background Sudden unexpected infant death (SUID) - including sudden infant death syndrome (SIDS) - continues to be a major contributor to infant mortality worldwide. Our objective was to analyse time trends and to identify country-clusters.
Jacqueline Müller-Nordhorn, Alice Schneider, Ulrike Grittner, Konrad Neumann, Thomas Keil, Stefan N. Willich, Sylvia Binting   +6 more
doaj   +1 more source

From first seizure to specific antiseizure medication in Dravet syndrome: Quantifying delays in the DS'coverED study

Epilepsia Open, EarlyView.
Abstract Objective Dravet syndrome (DS) is a rare early‐onset developmental and epileptic encephalopathy with persistent delays between seizure onset and diagnosis. The DS'coverED study aimed to characterize current diagnostic timelines by examining each step and its duration, identifying residual barriers, and actionable solutions to optimize the ...
Loucas Christodoulou, Maria Ballarà Petitbò, Sergio Aguilera Albesa, Simona Borroni, Perrine Hugon, Ratna Kumar, Tullio Messana, Pierre Meyer, Frédéric Villéga, Kerstin A. Klotz   +9 more
wiley   +1 more source

Subendocardial Fibrosis in Left Ventricular Hypertrabeculation-Cause or Consequence?

Clinical Medicine Insights: Cardiology, 2011
Left ventricular noncompaction has been classified as a primary cardiomyopathy with a genetic origin. This condition is morphologically characterized by a thickened, two-layered myocardium with numerous prominent trabeculations and deep, intertrabecular ...
J. Ker, L. Du Toit-Prinsloo, W.F.P. Van Heerden, G. Saayman   +3 more
doaj   +1 more source

Towards Better Understanding of the Pathogenesis of Neuronal Respiratory Network in Sudden Perinatal Death

Frontiers in Neurology, 2017
Sudden perinatal death that includes the victims of sudden infant death syndrome, sudden intrauterine death syndrome, and stillbirth are heartbreaking events in the life of parents.
Riffat Mehboob, Riffat Mehboob, Mahvish Kabir, Naseer Ahmed, Naseer Ahmed, Fridoon Jawad Ahmad   +5 more
doaj   +1 more source