Results 91 to 100 of about 22,016 (288)

Prevention of Sudden Unexpected Death in Epilepsy [PDF]

European Neurological Review, 2018
Sudden unexpected death in epilepsy (SUDEP) is the most common cause of death related to epilepsy and is associated with treatment resistance and the presence of generalised tonic-clonic seizures (GTCS, of either focal or generalised onset). While the causative mechanisms of SUDEP are yet to be fully elucidated, it is thought that seizure-induced ...
Torbjörn Tomson, Orrin Devinsky, Philippe Ryvlin   +2 more
openaire   +1 more source

Driving after vagus nerve stimulation therapy: Is it possible?

Epilepsia Open, EarlyView.
Abstract Driving is consistently reported as an important goal for people with epilepsy. We sought to determine the proportion of people with drug‐resistant epilepsy (DRE) who became medically fit to drive after treatment with vagus nerve stimulation (VNS).
Javier Peña‐Ceballos, Tenzin Choekyi, Niamh Colleran, Breege Staunton‐Grufferty, Nicola Dempsey, David Lewis‐Smith, Hany El Naggar, Kieron J. Sweeney, Donncha O'Brien, Patrick B. Moloney, Norman Delanty   +10 more
wiley   +1 more source

Progressive clonic slowing predicts severity of respiratory dysfunction and prolonged postictal immobility in tonic–clonic seizures

Epilepsia Open, EarlyView.
Abstract Objective Progressive clonic slowing is a common electroclinical phenomenon observed during the clonic phase of bilateral tonic–clonic seizures (BTCS) and reflects an inhibitory phenomenon. We aimed to explore the relationship between progressive clonic slowing and biomarkers implicated in the pathophysiology of sudden unexpected death in ...
John Phamnguyen, Fred Tremayne, Lata Vadlamudi, Cecilie Lander, Stephen Walsh, Xiaohua Chen, Alice‐Ann Sullivan, Viktor Vegh, David Reutens   +8 more
wiley   +1 more source

Green epileptology: Acceptance of telemedical follow‐up under climate protection aspects

Epilepsia Open, EarlyView.
Abstract Objective Expanding telemedicine services could reduce healthcare's environmental impact. This study aimed to assess the factors influencing the acceptance of telemedical follow‐up in epilepsy care, with a particular focus on transportation methods, digital literacy, and environmental awareness.
Rosa Luise Kilburg, Susanna Moskau‐Hartmann, Christoph Helmstaedter, Rainer Surges, Randi von Wrede   +4 more
wiley   +1 more source

A complex network perspective on brain disease

Biological Reviews, EarlyView.
ABSTRACT If brain anatomy and dynamics have a complex network structure as it has become standard to posit, it is reasonable to assume that such a structure should play a key role not only in brain function but also in brain dysfunction. However, exactly how network structure is implicated in brain damage and whether at least some pathologies can be ...
David Papo, Javier M. Buldú
wiley   +1 more source

Altered ventilatory responses to hypercapnia-hypoxia challenges in a preclinical SUDEP model involve orexin neurons

Neurobiology of Disease
Failure to recover from repeated hypercapnia and hypoxemia (HH) challenges caused by severe GCS and postictal apneas may contribute to sudden unexpected death in epilepsy (SUDEP).
Shruthi H. Iyer, Jillian E. Hinman, Ted Warren, Stephanie A. Matthews, Timothy A. Simeone, Kristina A. Simeone   +5 more
doaj   +1 more source

Are Variants Causing Cardiac Arrhythmia Risk Factors in Sudden Unexpected Death in Epilepsy?

Frontiers in Neurology, 2020
Sudden unexpected death in epilepsy (SUDEP) is the most common cause of premature mortality in individuals with epilepsy. Acute and adaptive changes in heart rhythm in epilepsy implicate cardiac dysfunction as a potential pathogenic mechanism in SUDEP ...
Lauren E. Bleakley, Ming S. Soh, Richard D. Bagnall, Richard D. Bagnall, Lynette G. Sadleir, Samuel Gooley, Christopher Semsarian, Christopher Semsarian, Ingrid E. Scheffer, Ingrid E. Scheffer, Ingrid E. Scheffer, Samuel F. Berkovic, Christopher A. Reid   +12 more
doaj   +1 more source

Episodic neurologic disorders: syndromes, genes, and mechanisms. [PDF]

, 2013
Many neurologic diseases cause discrete episodic impairment in contrast with progressive deterioration. The symptoms of these episodic disorders exhibit striking variety.
Fu, Ying-Hui, Ptáček, Louis J, Russell, Jonathan F   +2 more
core   +2 more sources

Genomics and epilepsy: Opportunities to improve understanding and management

Developmental Medicine &Child Neurology, EarlyView.
Accessing the entire genome, beyond any single causal variant for an individual's condition, may reveal additional genetic information of value in the understanding or care for that person. Combining such data with additional sources of information from that individual may enhance understanding and care further.
Sanjay M. Sisodiya
wiley   +1 more source

A utilidade do ácido graxo ômega-3 na epilepsia: mais do que uma criação de tilápias! [PDF]

, 2011
The epilepsies are one of the most common serious brain disorders and 20 to 30% of people developing epilepsy continue to have seizures and are refractory to treatment with the currently available therapies.
ARIDA, Ricardo M., CAVALHEIRO, Esper A., RABELLO, Guilherme M., SCORZA, Fulvio A., TERRA, Vera C.   +4 more
core   +3 more sources