Results 51 to 60 of about 6,328 (179)
Epilepsia, EarlyView.Abstract Objective Pooled mortality is nearly three times higher in people with epilepsy (PWE). Approximately 80% of sudden unexpected death in epilepsy (SUDEP) events occur during sleep, and primary sleep disorders are prevalent in the general population and PWE.
Marion Lazaj +7 more
wiley +1 more source
Possible role of SCN4A skeletal muscle mutation in apnea during seizure
Epilepsia Open, 2019 SCN4A gene mutations cause a number of neuromuscular phenotypes including myotonia. A subset of infants with myotonia‐causing mutations experience severe life‐threatening episodic laryngospasm with apnea.
Dilşad Türkdoğan +8 more
doaj +1 more source
Epilepsia, EarlyView.Abstract Objective This study was undertaken to evaluate the safety and effectiveness of responsive thalamic stimulation as adjunctive therapy for drug‐resistant idiopathic generalized epilepsy (IGE) with generalized tonic–clonic seizures (GTCSs). Methods NAUTILUS is a prospective, multicenter, single‐blind, randomized sham‐controlled pivotal trial ...
Utku Uysal +47 more
wiley +1 more source
Prolonged ictal and post‐ictal central apnea in an epileptic seizure
Epileptic Disorders, EarlyView.
Wei Zhao +4 more
wiley +1 more source
Tonic–clonic seizures captured during ambulatory video‐EEG are frequently unreported
Epilepsia, EarlyView.Abstract Objective Tonic–clonic seizures (TCSs) are widely regarded as clinically obvious, yet seizure counts used for treatment decisions and risk counseling often rely on patient or caregiver diaries. We sought to quantify the frequency of unreported TCSs during prolonged ambulatory video‐EEG (vEEG) monitoring and examined associations with ...
Ewan S. Nurse +3 more
wiley +1 more source
Are there mortality risks for patients with epilepsy who use cannabis treatments as monotherapy?
Epilepsy and Behavior Case Reports, 2019 Mortality associated with cannabis used for treatment of epilepsy is not well documented. We discuss two fatalities in the setting of epilepsy and self-determined therapy with cannabis (SDTC). One patient had probable sudden unexpected death in epilepsy,
Devon M. Kollmyer +3 more
doaj +1 more source
Unravelling the mysteries of sudden unexpected death in epilepsy
Neurología (English Edition), 2019 Introduction: Sudden unexpected death in epilepsy (SUDEP) is the most frequent cause of premature death in epileptic patients. Most SUDEP events occur at night and frequently go unnoticed; the exact pathophysiological mechanisms of this phenomenon ...
K.G. Hampel +2 more
doaj +1 more source
Gamma suppression correlates with thalamic stimulation therapeutic response in intractable epilepsy
Epilepsia, EarlyView.Abstract Objective In patients with drug‐resistant epilepsy who undergo anterior nucleus of the thalamus (ANT) deep brain stimulation (DBS), efficacy is assessed months after therapy initiation and clinicians have no guidance when choosing stimulation parameters due to the lack of real‐time biomarkers.
Zachary T. Sanger +10 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective Developmental and epileptic encephalopathies (DEEs) are characterized by drug‐resistant seizures and developmental slowing/regression. We examined the efficacy and tolerability of fenfluramine (FFA) in pediatric and adult patients with Lennox–Gastaut syndrome (LGS), Dravet syndrome (DS), and other DEEs.
Vicente Villanueva +29 more
wiley +1 more source
Epilepsia, EarlyView.Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer +7 more
wiley +1 more source