Results 81 to 90 of about 22,016 (288)

Brainstem atrophy in focal epilepsy destabilizes brainstem-brain interactions: Preliminary findings. [PDF]

open access: yes, 2019
BACKGROUND: MR Imaging has shown atrophy in brainstem regions that were linked to autonomic dysfunction in epilepsy patients. The brainstem projects to and modulates the activation state of several wide-spread cortical/subcortical regions.
Bateman, Lisa M.   +4 more
core   +1 more source

Consumo de álcool e morte súbita em epilepsia: uma abordagem experimental [PDF]

open access: yes, 2009
Using the pilocarpine model of epilepsy, we investigated the effects of alcohol consumption on the frequency of seizures in animals with epilepsy as well the underlying a possible association between alcohol intake and sudden unexpected death in epilepsy
ALMEIDA, Antonio-Carlos G. de   +7 more
core   +3 more sources

Current practices and trends in surgical decision‐making for children with Lennox–Gastaut syndrome: A cross‐sectional survey by the Pediatric Epilepsy Research Consortium

open access: yesEpilepsia Open, EarlyView.
Abstract Objective The objective of this study is to characterize contemporary surgical management practices and factors influencing surgical decision‐making in the management of Lennox–Gastaut Syndrome (LGS) across pediatric epilepsy centers in the United States.
Michelle Y. Chiu   +20 more
wiley   +1 more source

Rescue epilepsy medication and training: A comparison between midazolam use, guidelines, clinical practice, and possibilities in the UK and Norway

open access: yesEpilepsia Open, EarlyView.
Abstract Objectives Status epilepticus (SE) is a prolonged epileptic seizure carrying significant risk of long‐term disability and death. Rescue therapies are prescribed for prehospital administration to terminate SE. This study compared prescribing practices of rescue therapies of midazolam in the UK and Norway.
Audrey McBride   +7 more
wiley   +1 more source

The effect of cortical and subcortical parcel volumes on postictal generalized EEG suppression

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Alterations to brain structures and networks involved in central autonomic and respiratory control are possible biomarkers of SUDEP, but were mainly demonstrated in people at high risk. Postictal generalized EEG suppression (PGES) has been recorded in every case of near or confirmed SUDEP. The structural alterations underpinning PGES
Vladimir Bascarevic   +10 more
wiley   +1 more source

The Insula and Its Epilepsies [PDF]

open access: yes, 2019
Insular seizures are great mimickers of seizures originating elsewhere in the brain. The insula is a highly connected brain structure. Seizures may only become clinically evident after ictal activity propagates out of the insula with semiology that ...
Gonzalez-Martinez, Jorge   +8 more
core   +1 more source

Update on the Genetic Basis of Sudden Unexpected Death in Epilepsy [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
Epilepsy is a common neurological disorder associated with increased morbidity and mortality. Sudden unexpected death in epilepsy, also known as SUDEP, is the main cause of death in patients with epilepsy. SUDEP has an incidence of 1.2 per 1000 person-years in adults and 0.2 per 1000 person-years in children.
Coll M.   +4 more
openaire   +4 more sources

Using Cenobamate for managing idiopathic generalized epilepsy: A single‐center experience and systematic literature review

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To evaluate the single‐center experience of Cenobamate's (CNB) off‐label use in adults with idiopathic generalized epilepsy (IGE). Methods We conducted a retrospective review of electronic health records within a large healthcare system to identify IGE patients prescribed CNB.
Nicole Woodrich   +4 more
wiley   +1 more source

Epilepsy beyond seizures: a review of the impact of epilepsy and its comorbidities on health-related quality of life in dogs [PDF]

open access: yes
Epilepsy is one of the most common chronic neurological conditions in the dog, estimated to affect 0.6 to 0.75 per cent of dogs. Owners of dogs with epilepsy have previously indicated that their dog's quality of life (QoL) is of greatest importance to ...
Packer, R M A, Volk, H A
core   +1 more source

Age-specific periictal electroclinical features of generalized tonic-clonic seizures and potential risk of sudden unexpected death in epilepsy (SUDEP) [PDF]

open access: yes, 2013
Generalized tonic–clonic seizure (GTCS) is the commonest seizure type associated with sudden unexpected death in epilepsy (SUDEP). This study examined the semiological and electroencephalographic differences (EEG) in the GTCSs of adults as compared ...
Amina, Shahram   +11 more
core   +1 more source

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