Results 11 to 20 of about 5,831 (244)
Unexpected cardiorespiratory findings postictally and at rest weeks prior to SUDEP
IntroductionMechanisms underlying sudden unexpected death in epilepsy (SUDEP) are unclear, but autonomic disorders are thought to play a critical role. However, those dysfunctions have mainly been reported in the peri-ictal context of generalized tonic ...
Yassine Lamrani+10 more
doaj +2 more sources
Proteomics and Transcriptomics of the Hippocampus and Cortex in SUDEP and High-Risk SUDEP Patients [PDF]
To identify the molecular signaling pathways underlying sudden unexpected death in epilepsy (SUDEP) and high-risk SUDEP compared to control patients with epilepsy.For proteomics analyses, we evaluated the hippocampus and frontal cortex from microdissected postmortem brain tissue of 12 patients with SUDEP and 14 with non-SUDEP epilepsy.
Dominique F. Leitner+24 more
openaire +6 more sources
Interictal EEG and ECG for SUDEP Risk Assessment: A Retrospective Multicenter Cohort Study
ObjectiveSudden unexpected death in epilepsy (SUDEP) is the leading cause of epilepsy-related mortality. Although lots of effort has been made in identifying clinical risk factors for SUDEP in the literature, there are few validated methods to predict ...
Zhe Sage Chen+42 more
doaj +2 more sources
Why child neurologists talk about SUDEP: Results from two cross‐sectional surveys
Objective To characterize SUDEP discussion practices of child neurologists approximately 6 and 12 months after publication of the American Academy of Neurology SUDEP Clinical Practice Guideline and explore factors associated with discussion practice ...
Anne E. Keller+2 more
doaj +2 more sources
Audiogenic epileptic DBA/2 mice strain as a model of genetic reflex seizures and SUDEP
Epilepsy is a chronic neurological disease characterized by abnormal brain activity, which results in repeated spontaneous seizures. Sudden unexpected death in epilepsy (SUDEP) is the leading cause of seizure-related premature death, particularly in drug-
Francesca Bosco+11 more
doaj +2 more sources
Noradrenergic pathway from the locus coeruleus to heart is implicated in modulating SUDEP
Summary: Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death among epilepsy patients. However, the underlying mechanism remains elusive.
XiTing Lian+10 more
doaj +2 more sources
Seizure Clusters, Seizure Severity Markers, and SUDEP Risk
Rationale: Seizure clusters may be related to Sudden Unexpected Death in Epilepsy (SUDEP). Two or more generalized convulsive seizures (GCS) were captured during video electroencephalography in 7/11 (64%) patients with monitored SUDEP in the MORTEMUS ...
Manuela Ochoa-Urrea+51 more
doaj +2 more sources
A Peri-Ictal EEG-Based Biomarker for Sudden Unexpected Death in Epilepsy (SUDEP) Derived From Brain Network Analysis [PDF]
Sudden unexpected death in epilepsy (SUDEP) is the leading seizure-related cause of death in epilepsy patients. There are no validated biomarkers of SUDEP risk.
Uilki Tufa+7 more
openalex +2 more sources
Sudden unexpected death in epilepsy (SUDEP) is a major cause of death in people with epilepsy (PWE). Postictal apnea leading to cardiac arrest is the most common sequence of terminal events in witnessed cases of SUDEP, and postconvulsive central apnea ...
C. Faingold, H. Feng
semanticscholar +1 more source
ObjectiveTo investigate the quantitative electroencephalography (EEG) features associated with a high risk of sudden unexpected death in epilepsy (SUDEP) in patients with Dravet syndrome (DS).MethodsPatients with DS and healthy controls (HCs) who ...
Jeong-Youn Kim+5 more
doaj +1 more source