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SUDEP in the North American SUDEP Registry [PDF]
To obtain medical records, family interviews, and death-related reports of sudden unexpected death in epilepsy (SUDEP) cases to better understand SUDEP.All cases referred to the North American SUDEP Registry (NASR) between October 2011 and June 2018 were reviewed; cause of death was determined by consensus review. Available medical records, death scene
Verducci, Chloe +7 more
openaire +2 more sources
Interictal EEG and ECG for SUDEP Risk Assessment: A Retrospective Multicenter Cohort Study
ObjectiveSudden unexpected death in epilepsy (SUDEP) is the leading cause of epilepsy-related mortality. Although lots of effort has been made in identifying clinical risk factors for SUDEP in the literature, there are few validated methods to predict ...
Zhe Sage Chen +42 more
doaj +1 more source
Communication about sudden unexpected death in epilepsy: Understanding the caregiver perspective
Objective We aimed to characterize (1) the caregiver experience of learning about sudden unexpected death in epilepsy (SUDEP), and (2) caregiver preferences for SUDEP risk disclosure.
Isabella K. Pallotto +10 more
doaj +1 more source
Does having bad epilepsy make you a good surgical candidate? A number needed to treat analysis. [PDF]
Abstract Epilepsy surgery is an established treatment for drug‐resistant epilepsy, offering a realistic prospect of seizure freedom in well‐selected candidates. However, surgery is sometimes offered to individuals with a low probability of seizure freedom when it is framed as potentially “life‐saving” on the basis of the elevated mortality associated ...
Baxendale S, Heaney D, Walker MC.
europepmc +2 more sources
Objective The objective of the study was to assess level of knowledge and attitudes of SUDEP among people living with epilepsy (PLWE) and healthcare workers providing epilepsy care in Uganda.
Mark Kaddumukasa +6 more
doaj +1 more source
Unexpected cardiorespiratory findings postictally and at rest weeks prior to SUDEP
IntroductionMechanisms underlying sudden unexpected death in epilepsy (SUDEP) are unclear, but autonomic disorders are thought to play a critical role. However, those dysfunctions have mainly been reported in the peri-ictal context of generalized tonic ...
Yassine Lamrani +10 more
doaj +1 more source
Loss‐of‐function variants in Kv11.1 cardiac channels as a biomarker for SUDEP
Objective To compare the frequency and impact on the channel function of KCNH2 variants in SUDEP patients with epilepsy controls comprising patients older than 50 years, a group with low SUDEP risk, and establish loss‐of‐function KCNH2 variants as ...
Ming S. Soh +14 more
doaj +1 more source
Regional microglial populations in central autonomic brain regions in SUDEP [PDF]
OBJECTIVE: Sudden unexpected death in epilepsy (SUDEP) may arise as a result of autonomic dysfunction during a seizure. The central autonomic networks (CANs) modulate brainstem cardiorespiratory regulation. Recent magnetic resonance imaging (MRI) studies
Sanjay Sisodiya +9 more
core +1 more source
People with epilepsy are more likely to die prematurely and the most common epilepsy-related category of death is sudden unexpected death in epilepsy (SUDEP).
Vera C. Terra +7 more
doaj +1 more source
Alternating Hemiplegia and Cardiac Dysrhythmia
Investigators at the National Hospital for Neurology and Neurosurgery, Queen Square, London, and multiple centers in the UK, Europe, US, Melbourne, Australia, and Canada, analyzed ECG recordings of 52 patients with alternating hemiplegia from 9 countries;
J. Gordon Millichap
doaj +1 more source

