Results 11 to 20 of about 3,526 (182)

Proteomics and Transcriptomics of the Hippocampus and Cortex in SUDEP and High-Risk SUDEP Patients [PDF]

open access: yesNeurology, 2021
To identify the molecular signaling pathways underlying sudden unexpected death in epilepsy (SUDEP) and high-risk SUDEP compared to control patients with epilepsy.For proteomics analyses, we evaluated the hippocampus and frontal cortex from microdissected postmortem brain tissue of 12 patients with SUDEP and 14 with non-SUDEP epilepsy.
Dominique F. Leitner   +24 more
openaire   +5 more sources

SUDEP in the North American SUDEP Registry [PDF]

open access: yesNeurology, 2019
To obtain medical records, family interviews, and death-related reports of sudden unexpected death in epilepsy (SUDEP) cases to better understand SUDEP.All cases referred to the North American SUDEP Registry (NASR) between October 2011 and June 2018 were reviewed; cause of death was determined by consensus review. Available medical records, death scene
Verducci, Chloe   +7 more
openaire   +2 more sources

Let’s talk SUDEP [PDF]

open access: yesArchives of Neuropsychiatry, 2019
Sudden unexplained death in epilepsy (SUDEP) is a devastating complication of epilepsy which was under-recognized in the recent past despite its clear importance. In this review, we examine the definition of SUDEP, revise current pathophysiological theories, discuss risk factors and preventative measures, disclose tools for appraising the SUDEP risk ...
Ayşe Deniz, Elmali   +2 more
openaire   +2 more sources

Communication about sudden unexpected death in epilepsy: Understanding the caregiver perspective

open access: yesAnnals of the Child Neurology Society, 2023
Objective We aimed to characterize (1) the caregiver experience of learning about sudden unexpected death in epilepsy (SUDEP), and (2) caregiver preferences for SUDEP risk disclosure.
Isabella K. Pallotto   +10 more
doaj   +1 more source

Knowledge and attitudes about sudden death in epilepsy among people living with epilepsy and their healthcare providers in Mulago Hospital, Uganda: A cross‐sectional study

open access: yesEpilepsia Open, 2020
Objective The objective of the study was to assess level of knowledge and attitudes of SUDEP among people living with epilepsy (PLWE) and healthcare workers providing epilepsy care in Uganda.
Mark Kaddumukasa   +6 more
doaj   +1 more source

Loss‐of‐function variants in Kv11.1 cardiac channels as a biomarker for SUDEP

open access: yesAnnals of Clinical and Translational Neurology, 2021
Objective To compare the frequency and impact on the channel function of KCNH2 variants in SUDEP patients with epilepsy controls comprising patients older than 50 years, a group with low SUDEP risk, and establish loss‐of‐function KCNH2 variants as ...
Ming S. Soh   +14 more
doaj   +1 more source

Unexpected cardiorespiratory findings postictally and at rest weeks prior to SUDEP

open access: yesFrontiers in Neurology, 2023
IntroductionMechanisms underlying sudden unexpected death in epilepsy (SUDEP) are unclear, but autonomic disorders are thought to play a critical role. However, those dysfunctions have mainly been reported in the peri-ictal context of generalized tonic ...
Yassine Lamrani   +10 more
doaj   +1 more source

Does sudden unexpected death in children with epilepsy occur more frequently in those with high seizure frequency? Morte súbita em crianças com epilepsia ocorre naquelas que apresentam maior frequência de crises?

open access: yesArquivos de Neuro-Psiquiatria, 2009
People with epilepsy are more likely to die prematurely and the most common epilepsy-related category of death is sudden unexpected death in epilepsy (SUDEP).
Vera C. Terra   +7 more
doaj   +1 more source

Alternating Hemiplegia and Cardiac Dysrhythmia

open access: yesPediatric Neurology Briefs, 2015
Investigators at the National Hospital for Neurology and Neurosurgery, Queen Square, London, and multiple centers in the UK, Europe, US, Melbourne, Australia, and Canada, analyzed ECG recordings of 52 patients with alternating hemiplegia from 9 countries;
J. Gordon Millichap
doaj   +1 more source

Risk Assessment for Sudden Death in Epilepsy: The SUDEP-7 inventory

open access: yesFrontiers in Neurology, 2015
Background: Sudden Unexpected Death in Epilepsy (SUDEP) is a major cause of death in those with drug resistant epilepsy. There is a need for inventories and biomarkers associated with the risk for SUDEP.
Jennifer L Novak   +4 more
doaj   +1 more source

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