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Sudden unexplained death in epilepsy (SUDEP) is a devastating complication of epilepsy which was under-recognized in the recent past despite its clear importance. In this review, we examine the definition of SUDEP, revise current pathophysiological theories, discuss risk factors and preventative measures, disclose tools for appraising the SUDEP risk ...
Ayşe Deniz, Elmali +2 more
openaire +3 more sources
How Much is SUDEP Known by Patients by Epilepsy? [PDF]
Objective:Sudden unexpected death in epilepsy (SUDEP) is the most common cause of death in patients with epilepsy. The issue of informing every epilepsy patient and/or their relatives about SUDEP remains controversial. We evaluated the level of knowledge
Firdevs Ezgi Uçan Tokuç +3 more
doaj +2 more sources
Seizure Clusters, Seizure Severity Markers, and SUDEP Risk [PDF]
Rationale: Seizure clusters may be related to Sudden Unexpected Death in Epilepsy (SUDEP). Two or more generalized convulsive seizures (GCS) were captured during video electroencephalography in 7/11 (64%) patients with monitored SUDEP in the MORTEMUS ...
Manuela Ochoa-Urrea +51 more
doaj +4 more sources
Altered brain connectivity in sudden unexpected death in epilepsy (SUDEP) revealed using resting-state fMRI [PDF]
The circumstances surrounding SUDEP suggest autonomic or respiratory collapse, implying central failure of regulation or recovery. Characterisation of the communication among brain areas mediating such processes may shed light on mechanisms and ...
Allen LA +10 more
doaj +2 more sources
SUDEP risk is influenced by longevity genomics: a polygenic risk score studyResearch in context
Summary: Background: Sudden Unexpected Death in Epilepsy (SUDEP) is a rare and tragic outcome in epilepsy, identified by those with the condition as their most serious concern.
Helena Martins +26 more
doaj +2 more sources
SUDEP: Advances and Challenges [PDF]
During the past 2 decades, lay and academic awareness of sudden unexpected death in epilepsy (SUDEP) has increased tremendously, generating much discussion and research. In looking back, we tend to focus on progress, and there has been much.
Orrin Devinsky, Sanjay M. Sisodiya
openaire +4 more sources
Mind the Gap: SUDEP in the United States [PDF]
Socioeconomic Disparities in SUDEP in the US Cihan E, Hesdorffer DC, Brandsoy M, et al. Neurology . 2020;94(24): e2555-e2566.
Velez-Ruiz, Naymee J.
openaire +3 more sources
Serotonin transporter in the temporal lobe, hippocampus and amygdala in SUDEP [PDF]
Several lines of evidence link deficient serotonin function and SUDEP. Chronic treatment with serotonin reuptake inhibitors (SRIs) reduces ictal central apnoea, a risk factor for SUDEP.
Liu, J.Y.W. +9 more
core +1 more source
Epilepsy Research Institute UK Sudden Unexpected Death in Epilepsy (SUDEP) workshop: Identifying the pre-clinical and clinical priorities for SUDEP research [PDF]
The Epilepsy Research Institute’s Mortality, Morbidity and Risk Theme workshop on Sudden Unexpected Death in Epilepsy (SUDEP) brought together a diverse group of stakeholders, including basic science researchers, clinicians and clinical researchers ...
Ashby, Sammy +7 more
core +6 more sources
Why child neurologists talk about SUDEP: Results from two cross‐sectional surveys
Objective To characterize SUDEP discussion practices of child neurologists approximately 6 and 12 months after publication of the American Academy of Neurology SUDEP Clinical Practice Guideline and explore factors associated with discussion practice ...
Anne E. Keller +2 more
doaj +1 more source

