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Neurology, 2020
It was not that long ago that some believed there was little point in discussing sudden unexpected death in epilepsy (SUDEP) with patients. Why cause anxiety, it was argued, if the risk could not be influenced? The results of the landmark study by Sveinsson et al.1–3 reporting on a nationwide population-based case–control study of 255 SUDEP cases from ...
Lina, Nashef, Fergus, Rugg-Gunn
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It was not that long ago that some believed there was little point in discussing sudden unexpected death in epilepsy (SUDEP) with patients. Why cause anxiety, it was argued, if the risk could not be influenced? The results of the landmark study by Sveinsson et al.1–3 reporting on a nationwide population-based case–control study of 255 SUDEP cases from ...
Lina, Nashef, Fergus, Rugg-Gunn
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SUDEP—Pharmakologische Einflüsse
Zeitschrift für Epileptologie, 2006Das derzeitige Wissen uber medikamentose Einflusse auf die Inzidenz eines plotzlichen ungeklarten bzw. unerwarteten Todes bei Epilepsie (englisch: sudden unexplained/unexpected death in epilepsy patients; SUDEP) ist nicht schlussig. Obwohl Antiepileptika ebenso wie andere Medikamente wiederholt als moglicher Risikofaktor angeschuldigt wurden, lasst ...
Holger Schmidt, Günter Krämer
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SUDEP discussions with patients and families
Practical Neurology, 2012SUDEP is clearly a very important issue. Patients and their representatives (and in Scotland our legal system) would like consistency and clarity in how this information is conveyed. It behooves us to find a way to pass on our concerns in a way that acknowledges the needs, fears and circumstances of each individual patient and, where appropriate,of ...
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Neurology, 2007
The most frightening consequence of uncontrolled epilepsy is sudden unexplained death (SUDEP). Population studies suggest a risk in the range of 1 to 5 per 1,000 patient-years,1,2 and in high risk populations with neurologic impairments this rate is even higher. How seizures cause sudden death is still debated.
Norman K. So, Michael R. Sperling
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The most frightening consequence of uncontrolled epilepsy is sudden unexplained death (SUDEP). Population studies suggest a risk in the range of 1 to 5 per 1,000 patient-years,1,2 and in high risk populations with neurologic impairments this rate is even higher. How seizures cause sudden death is still debated.
Norman K. So, Michael R. Sperling
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SUDEP in inherited metabolic epilepsies
Epilepsy & BehaviorInherited metabolic epilepsies (IMEs) have an increased susceptibility for early mortality, including sudden unexpected death in epilepsy (SUDEP), as they often manifest with frequent drug-resistant seizures, including bilateral tonic-clonic and nocturnal seizures.
Itay Tokatly Latzer +4 more
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Neurology, 2017
Sudden unexpected death in epilepsy (SUDEP) was originally defined as a sudden, unexpected death in an individual with epilepsy, witnessed or not, and not associated with drowning or status epilepticus, for which a cause cannot be identified upon autopsy examination.1 Cases can be divided into definite, probable, and possible based upon the level of ...
Jeffrey, Buchhalter, Gregory D, Cascino
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Sudden unexpected death in epilepsy (SUDEP) was originally defined as a sudden, unexpected death in an individual with epilepsy, witnessed or not, and not associated with drowning or status epilepticus, for which a cause cannot be identified upon autopsy examination.1 Cases can be divided into definite, probable, and possible based upon the level of ...
Jeffrey, Buchhalter, Gregory D, Cascino
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Cardiac and Autonomic Mechanisms Contributing to SUDEP
Journal of Clinical Neurophysiology, 2015Sudden unexpected death in epilepsy is likely caused by a cascade of events affecting the vegetative nervous system leading to cardiorespiratory failure and death. Multiple genetic, electrophysiological, neurochemical, and pharmacological cardiac alterations have been associated with epilepsy, which can affect autonomic regulation of the heart and ...
Adriana C, Bermeo-Ovalle +2 more
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Retrospective comparison of interictal cardiac biomarkers of SUDEP or near-SUDEP with PNES patients
Epilepsy & BehaviorInterictal QTc-interval changes and heart rate variability (HRV) are reported in people succumbing to sudden unexpected death in epilepsy (SUDEP). We evaluated cardiac biomarkers recorded during video-EEG monitoring in nine SUDEP/near-SUDEP cases and compared them to 9 age- and gender-matched people with psychogenic nonepileptic episodes (PNES) treated
Alejandra Duque Ramirez +3 more
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Seizures and Sudden Death Beyond SUDEP
NeurologyMany physicians and researchers are familiar with the tragic phenomenon known as sudden infant death syndrome (SIDS), the leading cause of postneonatal mortality in high-resource countries. A less familiar category of unexplained deaths is the problem of sudden unexplained death in childhood (SUDC), a more rare and unusual presentation of sudden death ...
Richard D. Goldstein, Annapurna Poduri
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2013
A 19-year-old male had drug-resistant epilepsy and recurrent focal and generalized seizures. Trauma was reported in early childhood after he was struck by an automobile at the age of 5. This resulted in significant traumatic brain injury and cognitive impairment.
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A 19-year-old male had drug-resistant epilepsy and recurrent focal and generalized seizures. Trauma was reported in early childhood after he was struck by an automobile at the age of 5. This resulted in significant traumatic brain injury and cognitive impairment.
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