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Risk of sudden unexpected death in epilepsy (SUDEP) in children is influenced by different factors such as etiology, seizure type and frequency, treatment, and environment. A greater severity of epilepsy, in terms of seizure frequency, seizures type, especially with nocturnal generalized tonic-clonic seizures (GTCS), and resistance to anti-seizure ...
Marina Trivisano +5 more
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To identify all cases of sudden unexpected death in epilepsy (SUDEP) among people in Sweden during 1 year and to determine the SUDEP incidence in relation to age, sex, and psychiatric comorbidity.We included all individuals with a hospital-based ambulatory care or hospital discharge diagnosis of epilepsy in the Swedish National Patient Registry during ...
Olafur, Sveinsson +3 more
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Improving prediction of sudden unexpected death in epilepsy: From SUDEP‐7 to SUDEP‐3
Epilepsia, 2021AbstractObjectiveSudden unexpected death in epilepsy (SUDEP) is a significant cause of mortality in epilepsy. The aim of this study is to evaluate the validity of the SUDEP‐7 inventory and its components as tools for predicting SUDEP risk, and to develop and validate an improved inventory.MethodsThe study included 28 patients who underwent video ...
Roozbeh Tarighati Rasekhi +2 more
exaly +3 more sources
Resolving ambiguities in SUDEP classification
Epilepsia, 2018SummaryObjectiveTo examine the consistency of applying the Nashef et al (2012) criteria to classify sudden unexpected death in epilepsy (SUDEP).MethodsWe reviewed cases from the North American SUDEP Registry (n = 250) and Medical Examiner Offices (n = 1301: 698 Maryland, 457 New York City, 146 San Diego). Two epileptologists with expertise in SUDEP and
Orrin Devinsky +2 more
exaly +3 more sources
Genetics and SUDEP: Challenges and Future Directions
Seizure: the Journal of the British Epilepsy Association, 2023Sudden unexpected death in epilepsy (SUDEP) is the leading cause of epilepsy-related deaths in children and adults with epilepsy. The incidence of SUDEP in children and adults is equal, approximately 1.2 per 1000-person years. Although inroads have been made in our understanding of SUDEP, its pathophysiology remains unknown.
Robyn Whitney +2 more
exaly +3 more sources
Epilepsy and Behavior, 2017
The North American SUDEP Registry (NASR) is a repository of clinical data and biospecimens in cases of sudden unexpected death in epilepsy (SUDEP), a leading cause of epilepsy-related deaths. We assessed whether bereaved families were aware of SUDEP before their family member's death and their preferences for SUDEP disclosure.
Laura Crandall +2 more
exaly +3 more sources
The North American SUDEP Registry (NASR) is a repository of clinical data and biospecimens in cases of sudden unexpected death in epilepsy (SUDEP), a leading cause of epilepsy-related deaths. We assessed whether bereaved families were aware of SUDEP before their family member's death and their preferences for SUDEP disclosure.
Laura Crandall +2 more
exaly +3 more sources
Are we discussing SUDEP?–A retrospective case note analysis
Purpose: Sudden unexplained death in epilepsy (SUDEP) is uncommon. Discussing the risk of SUDEP can be difficult, particularly in those where the risk is considered low, and previous studies have suggested that clinical practice varies widely.
K E Mccoll, A Coker, Kate White
exaly +2 more sources
SUDEP: Living with the knowledge
Epilepsy Research, 2023To understand how knowledge of sudden unexpected death in epilepsy (SUDEP) impacted the lives of adult persons with epilepsy (PWE) and primary caregivers of both adults and children with epilepsy.The principles of fundamental qualitative description guided this descriptive and exploratory qualitative study to document patients' and caregivers ...
Robyn Whitney +5 more
openaire +2 more sources
Neurology, 2015
In 1904, Spratling noted that single, brief seizures kill 3%–4% of people with epilepsy.1 More recently, knowledge about sudden unexpected death in epilepsy (SUDEP) has grown dramatically. Our conceptualization of SUDEP has crystalized. We have evidence that SUDEPs largely follow seizures2 and our collective knowledge suggests that preventing seizures,
Orrin, Devinsky, Lina, Nashef
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In 1904, Spratling noted that single, brief seizures kill 3%–4% of people with epilepsy.1 More recently, knowledge about sudden unexpected death in epilepsy (SUDEP) has grown dramatically. Our conceptualization of SUDEP has crystalized. We have evidence that SUDEPs largely follow seizures2 and our collective knowledge suggests that preventing seizures,
Orrin, Devinsky, Lina, Nashef
openaire +2 more sources
The role of convulsive seizures in SUDEP
Autonomic Neuroscience, 2021Convulsive seizures are the most consistently reported risk factor for SUDEP. However, the precise mechanisms by which convulsive seizures trigger fatal cardiopulmonary changes are still unclear. Additionally, it is not clear why some seizures cause death when most do not.
Maromi, Nei, Allyson, Pickard
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